Module Catalogue 2024/25

BMN2004 : Cell and Molecular Biology of the Immune System

BMN2004 : Cell and Molecular Biology of the Immune System

  • Offered for Year: 2024/25
  • Module Leader(s): Dr Moe Kyaw Thu
  • Lecturer: Dr Nadine Nograles
  • Owning School: Biomedical, Nutritional and Sports Scien
  • Teaching Location: Malaysia
Semesters

Your programme is made up of credits, the total differs on programme to programme.

Semester 1 Credit Value: 10
ECTS Credits: 5.0
European Credit Transfer System
Pre-requisite

Modules you must have done previously to study this module

Code Title
CMB1003Microbiology and Immunology
Pre Requisite Comment

N/A

Co-Requisite

Modules you need to take at the same time

Co Requisite Comment

N/A

Aims

- To develop knowledge and understanding of the molecular and cell biology underlying a specific immune response, and to describe how such responses can protect against infection.

Outline Of Syllabus

Antibodies, T cell receptors and MHC molecules
Genetics of antigen recognition systems
Lymphocyte development
Lymphocyte activation
Regulation of immune responses
Antibody use in research/healthcare
Immunity against infection/immunisation

Learning Outcomes

Intended Knowledge Outcomes

•Describe the molecular structure of antibodies, T cell receptors and MHC class I and class II molecules

•Describe how antibody technology can be utilised

•Explain the part played by each of these molecules in antigen-recognition by T and B lymphocytes

•Describe the genetics of each of these types of molecule

•Discuss how the diverse repertoire of antibodies and T cell receptors is generated

•Explain how T cells are activated by antigens, and the consequences of this activation

•Explain what is meant by T-dependent and T-independent antigens and describe how these activate B cells

•Describe the stages of lymphocyte maturation from pluripotent haematopoietic stem cells

•Explain the need for immunological tolerance to self antigens and discuss how this is achieved

•Discuss how immune responses can be regulated, and the significance of qualitative regulation of immune responses

•Describe how specific immune responses can lead to the activation of effector mechanisms against infections with bacteria, viruses and eukaryotic parasites and how immunization aims to achieve protective responses

Intended Skill Outcomes

- To be able to interpret scientific information, in this instance immunological data relating to case studies

Teaching Methods

Teaching Activities
Category Activity Number Length Student Hours Comment
Scheduled Learning And Teaching ActivitiesLecture121:0012:00In person lectures
Scheduled Learning And Teaching ActivitiesSmall group teaching11:301:30In person - Seminar
Guided Independent StudyIndependent study186:3086:30Writing up lecture notes, revision and general reading.
Total100:00
Teaching Rationale And Relationship

Lectures are used to impart information in a concise manner, to highlight areas of importance and to interrelate with directed reading and self-directed study. The seminar is used for developing higher level skills of data interpretation and problem-solving as well as information retrieval. Private study is used for self-directed learning including further reading and preparation for examinations.

Reading Lists

Assessment Methods

The format of resits will be determined by the Board of Examiners

Exams
Description Length Semester When Set Percentage Comment
Digital Examination601A100In person Inspera Invigilated Quiz format/data interpretation based exam, max 75 questions.
Exam Pairings
Module Code Module Title Semester Comment
Cell and Molecular Biology of the Immune System1Sister module delivered at Newcastle University. To be timetable at 9:30 am and not on a Friday.
Assessment Rationale And Relationship

Knowledge and understanding is assessed through a summative examination.

Timetable

Past Exam Papers

General Notes

N/A

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Disclaimer

The information contained within the Module Catalogue relates to the 2024 academic year.

In accordance with University Terms and Conditions, the University makes all reasonable efforts to deliver the modules as described.

Modules may be amended on an annual basis to take account of changing staff expertise, developments in the discipline, the requirements of external bodies and partners, and student feedback. Module information for the 2025/26 entry will be published here in early-April 2025. Queries about information in the Module Catalogue should in the first instance be addressed to your School Office.