ONC8019 : Pharmacology of Chemotherapeutic Agents (E-learning)
- Offered for Year: 2017/18
- Module Leader(s): Prof. Nicola Curtin
- Lecturer: Dr David Jamieson
- Teaching Location: Off Campus
|Semester 1 Credit Value:||20|
The module explores the concepts underlying the pharmacological principles that govern the use of drugs in the treatment of cancer. The students will gain a detailed understanding of the mechanisms of action and resistance that underlie antitumour effects and toxicities of the drugs to treat cancer.
Outline Of Syllabus
This module includes the following topics:
•Hallmarks of cancer and targets of therapy
•Introduction to chemotherapy
•Principles of Pharmacokinetics and Pharmacodynamics of Anticancer drugs
•Alkylating agents and platinums
•Antimetabolites; nucleoside analogues
•Topoisomerase I and II poisons
•Tyrosine kinase inhibitors
|Guided Independent Study||Assessment preparation and completion||3||10:00||30:00||N/A|
|Guided Independent Study||Directed research and reading||12||6:00||72:00||Online content|
|Guided Independent Study||Skills practice||1||2:00||2:00||Software|
|Guided Independent Study||Reflective learning activity||22||2:00||44:00||eJournal and blogs|
|Guided Independent Study||Independent study||13||4:00||52:00||Supplemental reading|
Teaching Rationale And Relationship
Through a series of online tutorials (including videos and recapped PowerPoint presentations) as well as private study (including directed reading), students will gain detailed knowledge and understanding of the basic principles of chemotherapy and pharmacology ; chemotherapeutic, hormonal and targeted treatments for cancer, according to their mechanisms of action; and principles and mechanisms of tumour resistance to drug treatment. Furthermore, students will be encouraged to participate in collaborative learning via blogs. Personal development will be encouraged through the use of reflective journal postings, shared only with the module leaders. As the students proceed through the module, they will complete a number of interactive activities that will help to consolidate their understanding of the curriculum. The data compiled will guide their summative assessments.
This will facilitate the development of interpersonal and communication skills as well as team working and peer assessment skills.
The format of resits will be determined by the Board of Examiners
|Oral Presentation||10||1||M||60||Recorded Power Point presentation (maximum 10 Minutes)|
|Computer assessment||1||M||30||Online MCQ (Max 1hr -30 questions)|
|Portfolio||1||M||10||Participation in collaborative e-learning activities throughout the module.|
|Computer assessment||1||M||Weekly MCQs for each topic|
Assessment Rationale And Relationship
The presentation will require students to demonstrate their understanding of a chosen example of a major classes of chemotherapeutic agents and discuss clinical use, toxicities and mechanisms of resistance. The presentation will assess the students' ability to synthesise data and present information succinctly and in a visual format.
This will consolidate the students’ newly acquired knowledge across the whole range of the module as well as their ability to process information.
Multiple choice questions (formative) will help to promote reflection in students in order to identify areas of strength, weakness or misunderstanding. MCQs (summative) will probe specific points of understanding and knowledge of the students across the module.
A participation grade is included to encourage and reward the student's engagement with the
Should a student fail the participation assessment and have to undertake a re-sit they will have to
complete a different form of assessment. The student will be asked to look at 2 participation
activities as identified by the module leader/team and submit a 500 word written summary (approx. 250 words per activity).
- Reading List Website : rlo.ncl.ac.uk