The Medical Toxicology Centre was founded in January 2008. It followed a joint initiative between Public Health England and Newcastle University in 2006.
Our primary objective is to develop an international centre of expertise in toxicology to fill the national capability gap. We will undertake a program of specific research with direct relevance to human toxicology.
The strategic aims of MTC are to address:
- biomarkers of exposure and health effects
- genetic susceptibility and variability
- chronic and delayed health effects
- clinical toxicology research
Find out more about our Centre's members, and our facilities.
We receive funding via major grant income from several bodies. These include:
- the Home Office
- government agencies
- the EU
Current funding to exceeds £5m over 2015 to 2020.
Our common goal is of improving the health of the population.
We do this by focused research on:
- clinical consequences of exposure to chemicals
- identification of the toxic mechanisms involved
- development of evidence-based clinical management options and preventive measures
Our members come from a wide range of disciplines including:
They are members of the:
- Institute of Neuroscience
- Institute for Sustainability
- Institute of Cellular Medicine
- National Teratology Service
- National Poisons Information Service
Some members also have commitments to the Centre for Radiation, Chemical and Environmental Hazards of Public Health England.
They are experts in the response to chemical and radiation incidents in the UK. They use their expertise to advise on individual poisonings to chemicals and the public health response to major chemical incidents.
We also have commitments to the National Institute for Health Research Health Protection Research Unit NIHR HPRU in Chemical and Radiation Threats and Hazards.
The aim of this research is to identify chemical and radiation hazards and understand the risks to public and patient health.
The majority of our people and facilities are based in the Wolfson Building. Staff are also located in laboratories in the Medical School.
We have an analytical chemistry suite. This is complete with inductively coupled plasma emission mass spectrometry.
Our triple quadropole, ion trap and single quadropole mass spectrometers are coupled to gas and liquid chromatography.
We have a behavioral testing suite. This has automated tracking systems, arenas and mazes
We also have:
- an imaging laboratory with fluorescent microscope and electrochemiluminescence detector
- cell culture laboratories including stem cell facilities
- human tissue handling containment laboratory
We collaborate with colleagues in Newcastle University Institutes and Research Groups. These include the Psychobiology Research Group and the Drug and Chemical Toxicity Research Group.
This collaboration gives us access to a wide variety of additional techniques and expertise.