Our aim is to assess human exposure to chemicals and their metabolites (biomarkers of exposure) and develop, evaluate and use existing and new biomarkers of toxicity (biomarkers of effect).
There is currently little or no information regarding the levels of environmental chemicals in the blood and urine of any population base within the UK. Rather than predicting how much of a substance gets into people from estimates based on measurements in food, water, air, and other media, the reference range study aims to measure low levels of chemicals that are actually in people’s bodies. The overall purpose of this study is to provide unique exposure information to scientists, physicians, public health practitioners and other stakeholders e.g. Department of Health, to help prevent disease that results from exposure to environmental chemicals. This ongoing study will therefore measure levels of specific chemicals in blood samples of healthy donors.
The purpose of this study is to evaluate, and develop, rapid and robust analytical methods for the detection and quantification of nerve agent exposures in humans, following an accidental or deliberate release.