Assembly of pore proteins on gold electrodes (2001)

Author(s): Hong Q, Terrettaz S, Ulrich WP, Vogel H, Lakey JH

    Abstract: Protein-protein interactions at the cell surface are important in the activity of bacterial toxins such as colicins. We have developed methods to study these events using tethered lipid bilayers, which can be probed by impedance spectroscopy and surface plasmon resonance. Recently we have attached the receptor proteins directly to gold electrodes and this offers new possibilities for measuring protein-protein interactions on solid supports.

      • Date: 11-03-2001
      • Journal: Biochemical Society Transactions
      • Volume: 29
      • Issue: 4
      • Pages: 578-582
      • Publisher: Portland Press Ltd.
      • Publication type: Article
      • Bibliographic status: Published

      Professor Jeremy Lakey
      Professor of Struct. Biochemistry