All Projects
- A feasibility trial of screening and brief alcohol intervention to prevent hazardous drinking in young people aged 14-15 in a high school setting (SIPS JR-HIGH)
Project Leader(s): Dorothy Newbury-Birch - A randomised study of two anti-thyroid drug treatment regimens in young people with thyrotoxicosis
Project Leader(s): Dr Tim Cheetham - A Study of Donor Ex-Vivo Lung Perfusion in UK Lung Transplantation
Project Leader(s): Professor Andrew Fisher - An External Pilot Study to Test the Feasibility of a Randomised Controlled Trial comparing Eye Muscle Surgery against Active Monitoring for Childhood Intermittent Distance Exotropia [X(T)].
Project Leader(s): Mr Michael Clarke - anti-Fibrotic Effects of Losartan In Nash Evaluation study (FELINE Study)
Project Leader(s): Professor Chris Day - Antiglucocorticoid augmentation of anti-Depressants in Depression (ADD study)
Project Leader(s): Professor Nicol Ferrier - AutoDeCRA - Autologous Tolerogenic Dendritic Cells for Rheumatoid Arthritis
Project Leader(s): Professor JD Isaacs - B-Cell Depleting Therapy as a Treatment for Fatigue in Primary Biliary Cirrhosis
Project Leader(s): Professor David Jones - Biomarker-based Diagnosis of Ventilator-Associated Pneumonia (VAP): A Multi-centre Validation Study
Project Leader(s): Professor John Simpson - CONSERVE: A feasibility study for a multicentre randomised controlled trial to Compare Surgery (partial Nephrectomy) with needle ablation techniques (Radiofrequency ablation / cryotherapy) for the treatment of people with small renal masses (4 cm)
- DMD Heart Protection study
Project Leader(s): Dr John P Bourke - Efficacy of Switching to Lopinavir/Ritonavir in Improving Cognitive function in patients treated with Efavirenz (EFV) (SLICE Study)
Project Leader(s): Dr Ashley Price - EPICC: Extra Physiotherapy In Critical Care
Project Leader(s): Dr Simon Baudouin - Evaluation of Array Comparative Genomic Hibridisation in prenatal diagnosis of fetal anomalies: The EACH trial
Project Leader(s): Professor Stephen Robson (CI) - Filling Children’s Teeth: Indicated or Not? Feasibility Study
Project Leader(s): Dr Nicola Innes - FOR DMD - Duchenne muscular dystrophy: double-blind randomized trial to find optimum steroid regimen
Project Leader(s): Professor Kate Bushby - Insulin Resistance Intervention after Stroke: the IRIS Trial
Project Leader(s): Professor Walter Kernan - INVESTIGATE-I (INVasive Evaluation before Surgical Treatment for Incontinence Gives Added Therapeutic Effect?): a pragmatic multicentre pilot study to assess the feasibility of a future randomised controlled trial
Project Leader(s): Mr Paul Hilton (Chief Investigator) - Multi-centre UK Study of the Acetylcholinesterase Inhibitor Donepezil in Early Dementia Associated with Parkinson's Disease (MUSTARDD-PD )
Project Leader(s): Professor David J Burn - Observer blind randomised controlled pilot study comparing localised hand PUVA with localised hand narrowband UVB for the treatment of hand eczema
Project Leader(s): Dr Philip Hampton - Optimising Vitamin D Status in Older People: A Randomised Controlled Trial of Vitamin D Supplementation (VDOP)
Project Leader(s): Dr Terry J Aspray - Phase 1 study of use of 5% Carbogen in treatment of paediatric non-convulsive status epilepticus
Project Leader(s): Dr Rob Forsyth - PIL-FAST: Paramedic Initiated Lisinopril for Acute Stroke Treatment
Project Leader(s): Professor Gary Ford - Prevention of Recurrent Severe Hypoglycaemia: a Definitive RCT Comparing Optimised MDI and CSII with or without Adjunctive Real-time Continuous Glucose Monitoring: HypoCoMPaSS
Project Leader(s): Professor James Shaw - Randomised controlled trial, economic and qualitative process evaluation of domiciliary welfare rights advice for socio-economically disadvantaged older people recruited via primary health care (the Do-Well Study)
Project Leader(s): Professor Martin White - Reversal of over-anticoagulation using a ‘tailored’ vitamin K dosing regimen: towards a better management of anticoagulation therapy
Project Leader(s): Prof Farhad Kamali (CI) - SHIELD study: A phase II study (VEPEMB) in patients with Hodgkin’s Lymphoma aged ≥ 60 years
Project Leader(s): Prof Stephen J Proctor - SORTED – Study of Optimal Replacement of Thyroxine in the ElDerly
Project Leader(s): Dr Salman Razvi - SPIRIT - STI571 Prospective International RandomIsed Trial - A phase III, prospective randomised comparison of Imatinib in patients with newly diagnosed chronic phase CML
Project Leader(s): Professor Stephen O’Brien - SPIRIT2 - STI571 Prospective International RandomIsed Trial 2 - A phase III, prospective randomised comparison of Imatinib versus Dasatinib in patients with newly-diagnosed chronic phase chronic myeloid leukaemia
Project Leader(s): Professor Stephen O’Brien - STRIDE – Strategies To incRease confidence, InDependence and Energy. Cognitive behavioural therapy-based intervention to reduce fear of falling in older patients attending a community falls service: Therapy development and randomised controlled trial.
Project Leader(s): Dr Steve Parry - The effectiveness of Collaborative Care for people with dementia in primary care
Project Leader(s): Professor Steve Iliffe - To evaluate the safety and effectiveness of human ex vivo expanded autologous limbal stem cells for the treatment of unilateral total limbal stem cell deficiency
Project Leader(s): Mr Francisco C Figueiredo - Vascular Augmentation of Late-life Unremitted Depression (VALUeD)
Project Leader(s): Dr Alan Thomas
