- Project Leader: Prof Chris Seal
- Staff: Dr Anthony Watson; Mrs Wendy Bal
- Sponsors: Cereal Partners Worldwide
The aim of the inGRAINed HEALTH study is to investigate the impact of increased consumption of wholegrain (WG) wheat on markers of cardiovascular risk. The study is a controlled dietary intervention in a randomised, cross-over design with periods of 4-weeks separated by 4 week wash-out comparing the effects of consuming fixed daily amounts of a WG wheat breakfast cereal and wholemeal wheat bread (WG treatment) compared with a refined wheat breakfast cereal and white bread (control).
The objectives are:
- to assess the impact of the intervention on markers related to cardiovascular health, including lipid profile and 24-hour blood pressure
- to quantify the impact of WG consumption on alkylresorcinols in plasma and alkylresorcinols metabolites in urine as biomarkers of whole grain intake
The study runs until September 2015.