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Publication:

Isoindolinone Inhibitors of the Murine Double Minute 2 (MDM2)-p53 Protein-Protein Interaction: Structure-ActivityStudies Leading to Improved Potency (2011)

Author(s): Hardcastle IR, Liu J, Valeur E, Watson A, Ahmed SU, Blackburn TJ, Bennaceur K, Clegg W, Drummond C, Endicott JA, Golding BT, Griffin RJ, Gruber J, Haggerty K, Harrington RW, Hutton C, Kemp S, Lu X, McDonnell JM, Newell DR, Noble ME, Payne SL, Revill CH, Riedinger C, Xu Q, Lunec J

Date: 11-02-2011
Journal: Journal of Medicinal Chemistry
Volume: 54
Issue: 5
Pages: 1233-1243
Publisher: American Chemical Society
Publication type: Article
Bibliographic status: Published

URL: http://dx.doi.org/10.1021/jm1011929
DOI: 10.1021/jm1011929
PubMed id: 21314128
ISSN (electronic): 1520-4804

Staff
Professor Jane Endicott Prof of Cancer Structural Biology	Email: jane.endicott@ncl.ac.uk Telephone: +44 (0) 191 246 4422
Professor Roger Griffin Professor of Medicinal Chemistry	Email: roger.griffin@ncl.ac.uk Telephone: +44 (0) 191 222 8591
Dr Karen Haggerty Senior Research Technician	Email: karen.haggerty@ncl.ac.uk Telephone: +44 (0) 191 222 5934
Dr Ian Hardcastle Senior Lecturer in Medicinal Chemistry	Email: ian.hardcastle@ncl.ac.uk Telephone: +44 (0) 191 222 6645
Dr Claire Hutton Senior Research Technician	Email: claire.hutton@ncl.ac.uk Telephone: +44 (0) 191 246 4368
Professor John Lunec Gillespie Prof of Molecular Oncology	Email: john.lunec@ncl.ac.uk Telephone: +44 (0) 191 246 4420
Professor Herbie Newell Professor of Cancer Therapeutics	Email: herbie.newell@ncl.ac.uk Telephone: +44 (0) 191 246 4300
Professor Martin Noble Prof of Biom Struct & Anticanc Drug Des	Email: martin.noble@ncl.ac.uk Telephone: +44 (0) 191 246 4466

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