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Publication:

MDM2-p53 protein-protein interaction inhibitors: A-ring substituted isoindolinones (2011)

Author(s): Watson AF, Liu JF, Bennaceur K, Drummond CJ, Endicott JA, Golding BT, Griffin RJ, Haggerty K, Lu XH, McDonnell JM, Newell DR, Noble MEM, Revill CH, Riedinger C, Xu Q, Zhao Y, Lunec J, Hardcastle IR

      • Date: 09-08-2011
      • Journal: Bioorganic & Medicinal Chemistry Letters
      • Volume: 21
      • Issue: 19
      • Pages: 5916-5919
      • Publisher: Pergamon
      • Publication type: Article
      • Bibliographic status: Published

      Keywords: MDM2 p53 Protein-protein interaction inhibitor Isoindolinone P53 PATHWAY TRANSACTIVATION ANTAGONISTS ACTIVATION CELLS

      Staff

      Professor Jane Endicott
      Prof of Cancer Structural Biology

      Professor Roger Griffin
      Professor of Medicinal Chemistry

      Dr Karen Haggerty
      Senior Research Technician

      Dr Ian Hardcastle
      Senior Lecturer in Medicinal Chemistry

      Professor John Lunec
      Gillespie Prof of Molecular Oncology

      Professor Herbie Newell
      Professor of Cancer Therapeutics

      Professor Martin Noble
      Prof of Biom Struct & Anticanc Drug Des

      Dr Yan Zhao
      Research Associate