Newcastle University

Publications

Year: 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 1986 1984 1983 1980 1979

• Swaminathan S, Huang C, Geng H, Chen Z, Harvey R, Kang H, Ng C, Titz B, Hurtz C, Sadiyah F, Nowak D, Thoennissen GB, Rand V, Graeber TG, Koeffler HP, Carroll WL, Willman CL, Hall AG, Igarashi K, Melnick A, Müschen M. BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint. Nature Medicine 2013. In Press.
• Buitenkamp TD, Pieters R, Zimmermann M, de Haas V, Richards SM, Vora AJ, Mitchell CD, Schwab C, Harrison CJ, Moorman AV, van den Heuvel-Eibrink MM, Zwaan CM. BTG1 deletions do not predict outcome in Down syndrome acute lymphoblastic leukemia. Leukemia 2013, 27(1), 251-252.
• Asbeck AHv, Beyerle A, McNeill H, Bovee-Geurts PH, Lindberg S, Verdurmen WPR, Hällbrink M, Langel U, Heidenreich O, Brock R. A Definition of the Molecular Parameters for the Formation of Transfection-Effective siRNA-Cell-Penetrating Peptide Nanoparticles. ACS Nano 2013. In Press.
• Clifford S, Crosier S, Nicholson S, Robson K, Jacques T, Wharton S, Bown N, Michalski A, Pizer B. A national feasibility study of real-time central pathology review (CPR) and molecular diagnostics for medulloblastoma. In: 114th Meeting of the British Neuropathological Society: Symposium on Advances in Motor Neuron Diseases. 2013, London: Wiley-Blackwell Publishing Ltd.
• Moad M, Pal D (joint first author), Hepburn AC, Williamson SC, Wilson L, Lako M, Armstrong L, Hayward SW, Franco O, Cates J, Fordham SE, Przyborskid S, Carr-Wilkinson J, Robson CN, Heer R. A novel model of urinary tract differentiation, tissue regeneration and disease: Reprogramming of human prostate and bladder cells into induced pluripotent stem cells. European Urology 2013. In Press.
• Williamson SC, Hartley AE, Heer R. A review of tasquinimod in the treatment of advanced prostate cancer. Drug Design, Development and Therapy 2013, 7, 167-174.
• Al-Shehhi H, Konn ZJ, Schwab CJ, Erhorn A, Barber KE, Wright SL, Gabriel AS, Harrison CJ, Moorman AV. Abnormalities of the der(12)t(12;21) in ETV6-RUNX1 acute lymphoblastic leukemia. Genes, Chromosomes & Cancer 2013, 52(2), 202-213.
• Rehe K, Wilson K, Bomken S, Williamson D, Irving J, den Boer ML, Stanulla M, Schrappe M, Hall AG, Heidenreich O, Vormoor J. Acute B lymphoblastic leukaemia-propagating cells are present at high frequency in diverse lymphoblast populations. EMBO Molecular Medicine 2013, 5(1), 38-51.
• Veal GJ, Errington J, Rowbotham SE, Illingworth NA, Malik G, Cole M, Daly AK, Pearson ADJ, Boddy AV. Adaptive dosing approaches to the individualization of 13-cis-retinoic acid (isotretinoin) treatment for children with high-risk neuroblastoma. Clinical Cancer Research 2013, 19(2), 469-479.
• Hill CR, Jamieson D, Thomas HD, Brown CDA, Boddy AV, Veal GJ. Characterisation of the roles of ABCB1, ABCC1, ABCC2 and ABCG2 in the transport and pharmacokinetics of actinomycin D in vitro and in vivo. Biochemical Pharmacology 2013, 85(1), 29-37.
• Hole AJ, Baumli S, Shao H, Shi SH, Huang SL, Pepper C, Fischer PM, Wang SD, Endicott JA, Noble ME. Comparative Structural and Functional Studies of 4-(Thiazol-5-yl)-2-(phenylamino)pyrimidine-5-carbonitrile CDK9 Inhibitors Suggest the Basis for Isotype Selectivity. Journal of Medicinal Chemistry 2013, 56(3), 660-670.
• Paulsson K, Harrison CJ, Andersen MK, Chilton L, Nordgren A, Moorman AV, Johansson B. Distinct patterns of gained chromosomes in high hyperdiploid acute lymphoblastic leukemia with t(1;19)(q23;p13), t(9;22)(q34;q22) or MLL rearrangements. Leukemia 2013, (epub ahead of print).
• Schwalbe EC, Williamson D, Lindsey JC, Hamilton D, Ryan SL, Megahed H, Garami M, Hauser P, Dembowska-Baginska B, Perek D, Northcott PA, Taylor MD, Taylor RE, Ellison DW, Bailey S, Clifford SC. DNA methylation profiling of medulloblastoma allows robust subclassification and improved outcome prediction using formalin-fixed biopsies. Acta Neuropathologica 2013, (epub ahead of print).
• Cornell L, Munck J, Alsinet C, Villanueva A, Thomas H, Jackson J, Televantou D, Burt A, Llovet JM, Curtin N, Reeves HL. DNA-PK in hepatocellular cancer - a driver of progression and chemoradioresistance?. Will try Nature Medicine or Gastroenterology 2013. In Preparation.
• Petrie JL, Al-Oanzi ZH, Arden C, Tudhope SJ, Mann J, Kieswich J, Yaqoob MM, Towle HC, Agius L. Glucose induces protein targeting to glycogen in hepatocytes by fructose 2,6-bisphosphate-mediated recruitment of MondoA to the promoter. Molecular and Cellular Biology 2013, 33(4), 725-738.
• Lees D, Manning W, Joyce T, McCaskie A, Gerrand C. Henry's Pelvic Deltoid: Antiquated Concept or Important Consideration for Total Hip Arthroplasty? An Anatomical Study. Journal of Arthroplasty 2013, 28(2), 338-341.e1.
• Reeves HL, Chattopadyhay D, Lochan R, Graham J, Das D, Aslam T, Patanwala I, Gaggar S, Cole M, Jaques B, Sumpter K, Stewart S, Rose J, Hudson M, Manas D. Hepatocellular Cancer – the impact of obesity and type 2 diabetes. Journal of Hepatology 2013. Submitted.
• Chilton L, Hills RK, Harrison CJ, Burnett AK, Grimwade D, Moorman AV. Hyperdiploidy with 49 to 65 chromosomes represents a heterogeneous cytogenetic subgroup of acute myeloid leukemia with differential outcome. 2013. Submitted.
• Sung PJ, Boulos N, Tilby MJ, Andrews WD, Newbold RF, Tweddle DA, Lunec J. Identification and characterisation of STMN4 and ROBO2 gene involvement in neuroblastoma cell differentiation. Cancer Letters 2013, 328(1), 168-175.
• Jenkinson S, Koo K, Mansour MR, Goulden N, Vora A, Mitchell C, Wade R, Richards S, Hancock J, Moorman AV, Linch DC, Gale RE. Impact of NOTCH1/FBXW7 mutations on outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on the MRC UKALL 2003 trial. Leukemia 2013, 27(1), 41-47.
• Plummer ER. Inhibitor of ATR (Ataxia Telangiectasia and RAD3 Related) Kinase. In: 11th International Congress on Targeted Anticancer Therapies (TAT 2013). 2013, Paris, France: Oxford University Press.
• Willet JDP, Pichitsiri W, Jenkinson SE, Brain JG, Wood K, Alhasan AA, Spielhofer J, Ali S, Kirby JA. Kidney transplantation: analysis of the expression and T cell-mediated activation of latent TGF-beta. Journal of Leukocyte Biology 2013, 93(epub ahead of print).
• Bomken S, Buechler L, Rehe K, Ponthan F, Elder A, Blair H, Bacon CM, Vormoor J, Heidenreich O. Lentiviral marking of patient-derived acute lymphoblastic leukaemic cells allows in vivo tracking of disease progression. Leukemia 2013, 27(3), 718-721.
• Safavi S, Forestier E, Golovleva I, Barbany G, Nord KH, Moorman AV, Harrison CJ, Johansson B, Paulsson K. Loss of chromosomes is the primary event in near-haploid and low-hypodiploid acute lymphoblastic leukemia. Leukemia 2013, 27(1), 248-250.
• Culpin RE, Sieniawski M, Proctor SJ, Menon G, Mainou-Fowler T. MicroRNAs are suitable for assessment as biomarkers from formalin-fixed paraffin-embedded tissue, and miR-24 represents an appropriate reference microRNA for diffuse large B-cell lymphoma studies. Journal of Clinical Pathology 2013, 66(3), 249-252.
• Gaymes TJ, Mohamedali AM, Patterson M, Matto N, Smith A, Kulasekararaj A, Chelliah R, Curtin N, Farzaneh F, Shall S, Mufti G. Microsatellite instability induced mutations in DNA repair genes Ctip and MRE11 confer hypersensitivity to poly (ADP-ribose) polymerase (PARP) inhibitors in myeloid malignancies. Haematologica 2013. In Press.
• Singhapol C, Pal D, Czapiewski R, Porika M, Nelson G, Saretzki GC. Mitochondrial Telomerase Protects Cancer Cells from Nuclear DNA Damage and Apoptosis. PLoS One 2013, 8(1), e52989.
• Patman GL, Televantou D, Whitehead A, Oakley F, Mann DA, Burt AD, Anstee QA, Reeves HL. NAFLD progression to NASH, fibrosis and hepatocellular cancer - development of a robust animal model. Journal of Hepatology 2013. In Preparation.
• Bate J, Gibson F, Johnson E, Selwood K, Skinner R, Chisholm J. Neutropenic sepsis: prevention and management of neutropenic sepsis in cancer patients (NICE Clinical Guideline CG151). Archives of Disease in Childhood: Education and Practice Edition 2013, 98(2), 73-75.
• Binda O. On your histone mark, SET, methylate!. Epigenetics 2013, 8(5), 457-463.
• Clark EL, Hadjimichael C, Temperley R, Barnard A, Fuller-Pace FV, Robson CN. p68/DdX5 Supports β-Catenin & RNAP II during Androgen Receptor Mediated Transcription in Prostate Cancer. PLoS One 2013, 8(1), e54150.
• Kontny NE, Wurthwein G, Joachim B, Boddy AV, Krischke M, Fuhr U, Thompson PA, Jorger M, Schellens JHM, Hempel G. Population pharmacokinetics of doxorubicin: establishment of a NONMEM model for adults and children older than 3 years. Cancer Chemotherapy and Pharmacology 2013, 71(3), 749-763.
• Bechmann LP, Vetter D, Ishida J, Hannivoort RA, Lang UE, Kocabayoglu P, Fiel MI, Muñoz U, Patman GL, Ge F, Yakar S, Li X, Agius L, Lee YM, Zhang W, Hui KY, Televantou D, Schwartz GJ, Leroith D, Berk PD, Nagai R, Suzuki T, Reeves HL, Friedman SL. Post-transcriptional activation of PPAR alpha by KLF6 in hepatic steatosis. Journal of Hepatology 2013, 58(5), 1000-1006.
• Pekalski M, Jenkinson SE, Willet JDP, Poyner EFM, Alhamidi AH, Robertson H, Ali S, Kirby JA. Renal allograft rejection: Examination of delayed differentiation of Treg and Th17 effector T cells. Immunobiology 2013, 218(3), 303-310.
• Moorman AV, Robinson H, Schwab C, Richards SM, Hancock J, Mitchell CD, Goulden N, Vora A, Harrison CJ. Risk directed treatment intensification significantly reduces the risk of relapse among children with acute lymphoblastic leukaemia and intrachromosomal amplification of chromosome 21. Journal of Clinical Oncology 2013. Submitted.
• Mehanna H, McQueen A, Robinson M, Paleri V. Salivary gland swellings. Clinical Otolaryngology 2013, 38(1), 58-65.
• Fordham SE, Marr H, Allan JM. Searching for clarity in therapy-related myelodysplastic syndrome/acute myeloid leukemia prognostication. Leukemia and Lymphoma 2013, 54(3), 447-448.
• Binda O, Sevilla A, LeRoy G, Lemischka IR, Garcia BA, Richard S. SETD6 monomethylates H2AZ on lysine 7 and is required for the maintenance of embryonic stem cell self-renewal. Epigenetics 2013, 8(2), 177-183.
• Bell N, Hann V, Redfern CPF, Cheek TR. Store-operated Ca²⁺ entry in proliferating and retinoic acid-differentiated N- and S-type neuroblastoma cells. Biochimica et Biophysica Acta: Molecular Cell Research 2013, 1833(3), 643-651.
• Pastok MW, Prescott MC, Dart C, Murray PA, Rees HH, Fisher MJ. Structural diversity of the cAMP-dependent protein kinase regulatory subunit in Caenorhabditis elegans. Cellular Signalling 2013, 25(1), 168-177.
• Shao H, Shi SH, Huang SL, Hole AJ, Abbas AY, Baumli S, Liu XR, Lam F, Foley DW, Fischer PM, Noble M, Endicott JA, Pepper C, Wang SD. Substituted 4-(Thiazol-5-yl)-2-(phenylamino)pyrimidines Are Highly Active CDK9 Inhibitors: Synthesis, X-ray Crystal Structures, Structure-Activity Relationship, and Anticancer Activities. Journal of Medicinal Chemistry 2013, 56(3), 640-659.
• Alhasan S, Patman GL, Televantou D, Beale G, Wedge S, Newell DR, Reeves HL. Sulfatase-2 (SULF2) expression in hepatocellular cancer cells or tumour activated stromal cells associates with membranous translocation of beta catenin and a poor prognosis. Cancer Research 2013. In Preparation.
• Biggar MA, Lennard TWJ. Systematic review of phaeochromocytoma in pregnancy. British Journal of Surgery 2013, 100(2), 182-190.
• Marks DI, Moorman AV, Chilton L, Paietta E, Enshaie A, DeWald G, Harrison C, Fielding AK, Foroni L, Goldstone AH, Litzow MR, Luger SM, McMillan AK, Racevskis J, Rowe JM, Tallman MS, Wiernik P, Lazarus HM. The clinical characteristics, therapy and outcome of 85 adults with acute lymphoblastic leukemia and t(4;11)(q21;q23)/MLL-AFF1 prospectively treated on UKALLXII/ECOG2993. Haematologica 2013, (epub ahead of print).
• Coffey K, Rogerson L, Ryan-Munden C, Alkharaif D, Stockley J, Heer R, Sahadevan K, O'Neill D, Jones D, Darby S, Staller P, Mantilla A, Gaughan L, Robson CN. The lysine demethylase, KDM4B, is a key molecule in androgen receptor signalling and turnover. Nucleic Acids Research 2013, Epub ahead of print.
• Chagaluka G, Carey P, Banda K, Schwab C, Chilton L, Schwalbe E, Skinner R, Israels T, Moorman A, Molyneux E, Bailey S. Treating childhood acute lymphoblastic leukemia in Malawi. Haematologica 2013, 98(1), e1-e3.
• Peters C, Sykora KW, Veys P, Lankester A, Slatter M, Skinner R, Wachowiak J, Poetschger U. Treosulfan for Conditioning in Children and Adolescents Before Hematopoietic Stem Cell Transplantation (HSCT). In: BMT Tandem Meetings. 2013, Salt Lake City, Utah, USA: Elsevier Inc.
• Lebraud H, Cano C, Carbain B, Hardcastle IR, Harrington RW, Griffin RJ, Golding BT. Trifluoroethanol solvent facilitates selective N-7 methylation of purines. Organic & Biomolecular Chemistry 2013, 11(11), 1874-1878.