Newcastle University

Publications

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• Henry JA, Hennessy C, Levett DL, Lennard TWJ, Westley BR, May FEB. INT-2 amplification in breast cancer: association with decreased survival and relationship to amplification of C-ERBB-2 and C-MYC. International Journal of Cancer 1993, 53(5), 774-780.
• Healicon RM, Westley BR, May FEB. Isolation and characterization of an estrogen responsice breast cancer cell line, EFF-3. International Journal of Cancer 1993, 53(3), 388-394.
• May FEB, Smith DJ, Westley BR. The human cathepsin d-encoding is transcribed from an estrogen regulated and a constitutive start point. Gene 1993, 134(2), 277-282.
• Wiseman LR, Johnson MD, Wakeling AE, Lykkesfeldt AE, May FEB, Westley BR. Type-I IGF receptor and acquired tamoxifen resistance in estrogen responsive human breast cancer cells. European Journal of Cancer 1993, 29A(16), 2256-2264.
• Inglehearn CF, Carter SA, Keen TJ, Lindsey JC, Stephenson AM, Bashir R, Al-Maghtheh M, Moore AT, Jay M, Bird AC, Bhattacharya SS. A new locus for autosomal dominant retinitis pigmentosa on chromosome 7p. Nature Genetics 1993, 4(1), 51-53.
• Reeve A, Norman P, Sinclair P, Whittington-Smith R, Hamey Y, Donnai D, Read A. A true telomeric translocation in a baby with Prader-Willi phenotype. American Journal of Medical Genetics 1993, 47, 1-6.
• Cole M, Parker L, Craft AW, Bell S, Dale G, McGill AC, Seviour JA, Smith J. Creatinine related reference ranges for urinary homovanillic-acid and vanillylmandelic acid at 6 months of age. Archives of Disease in Childhood 1993, 68(3), 376-378.
• Noble MEM, Musacchio A, Saraste M, Courtneidge SA, Wierenga RK. Crystal structure of the SH3 domain in human Fyn; comparison of the three-dimensional structures of SH3 domains in tyrosine kinases and spectrin. EMBO Journal 1993, 12(7), 2617-2624.
• Willmore E, Durkacz BW. Cytotoxic mechanisms of 5-fluoropyrimidines: Relationships with poly(ADP-ribose) polymerase activity, DNA strand breakage and incorporation into nucleic acids. Biochemical Pharmacology 1993, 46(2), 205-211.
• Lowis SP, Pearson ADJ, Newell DR, Cole M. Etoposide pharmacokinetics in children: the development and prospective validation of a dosing equation. Cancer Research 1993, 53(20), 4881-4889.
• Thomas DJ, Birch PJ, Vickers J, Robinson M, Clifford SC, Hall A, Neal DE. Glutathione-S-transferase π expression in transitional cell carcinoma of the bladder. British Journal of Urology 1993, 72(5 part 2), 740-743.
• JACKSON GH, CAREY PJ, CANT AJ, BOWN NP, REID MM. MYELODYSPLASTIC SYNDROMES IN CHILDREN. BRITISH JOURNAL OF HAEMATOLOGY 1993, 84(1), 185-186.
• Borchert TV, Pratt K, Zeelen JP, Callens M, Noble MEM, Opperdoes FR, Michels PAM, Wierenga RK. Overexpression of trypanosomal triosephosphate isomerase in Escherichia coli and characterisation of a dimer-interface mutant. European Journal of Biochemistry 1993, 211(3), 703-710.
• Mainfroid V, Goraj K, Rentierdelrue F, Houbrechts A, Loiseau A, Gohimont AC, Noble MEM, Borchert TV, Wierenga RK, Martial JA. Replacing the (βα)-unit 8 of E.coli TIM with its chicken homologue leads to a stable and active hybrid enzyme. Protein Engineering 1993, 6(8), 893-900.
• Noble MEM, Zeelen JP, Wierenga RK, Mainfroid V, Goraj K, Gohimont AC, Martial JA. Structure of triosephosphate isomerase from Escherichia coli determined at 2.6 Å resolution. Acta Crystallographica Section D: Biological Crystallography 1993, 49(part 4), 403-417.
• Noble MEM, Zeelen JP, Wierenga RK. Structures of the “open” and “closed” state of trypanosomal triosephosphate isomerase, as observed in a new crystal form: Implications for the reaction mechanism. Proteins: Structure, Function, and Bioinformatics 1993, 16(4), 311-326.
• Noble MEM, Cleasby A, Johnson LN, Egmond MR, Frenkenb LGJ. The crystal structure of triacylglycerol lipase from Pseudomonas glumae reveals a partially redundant catalytic aspartate. FEBS Letters 1993, 331(1-2), 123-128.
• Moynihan PJ, Adamson AJ, Skinner R, Rugg-Gunn AJ, Appleton DR, Butler TJ. The intake of nutrients by Northumbrian adolescents from one-parent families and from unemployed families. Journal of Human Nutrition and Dietetics 1993, 6(5), 433-441.