Publications
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- Lovat, P.E., Irving, H., Malcolm, A.J., Pearson, A.D.J., Redfern, C.P.F. 9-cis retinoic acid - A better retinoid for the modulation of differentiation, proliferation and gene expression in human neuroblastoma.
Journal of Neuro-Oncology 1997, 31(1-2), 85-91.
- Wedge SR, Porteous JK, Glaser MG, Marcus K, Newlands ES. In vitro evaluation of temozolomide combined with X-irradiation.
Anti-Cancer Drugs 1997, 8(1), 92-97.
- Siddiqui N, Boddy AV, Thomas HD, Bailey N, Robson L, Lind M, Calvert AH. A clinical and pharmacokinetic study of the combination of carboplatin and paclitaxel for epithelial ovarian cancer.
British Journal of Cancer 1997, 75(2), 287-294.
- Lovat, P.E., Irving, H., Annicchiarico-Petruzzelli, M., Bernassola, F., Malcolm, A.J., Pearson, A.D.J., Melino, G., Redfern, C.P.F. Apoptosis of N-type neuroblastoma cells after differentiation with 9- cis-retinoic acid and subsequent washout.
Journal of the National Cancer Institute 1997, 89(6), 446-452.
- Peng, B., English, M. W., Boddy, A. V., Price, L, Wyllie, R., Pearson, A. D. J. , Tilby, M. J., Newell, D. R. Cisplatin pharmacokinetics in children with cancer.
European Journal of Cancer 1997, 33(11), 1823-1828.
- May FEB, Westley BR. Close physical linkage of the genes encoding the pNR-2/pS2 protein and human spasmolytic protein (hSP).
Human Genetics 1997, 99(3), 303-307.
- Yule, S., Price, L., Pearson, A. D. J., Boddy, A. V. Cyclophosphamide and ifosfamide metabolites in the cerebrospinal fluid of children.
Clinical Cancer Research 1997, 3(11), 1985-1992.
- Wedge SR, Porteous JK, Newlands ES. Effect of single and multiple administration of an O6-benzylguanine/temozolomide combination: an evaluation in a human melanoma xenograft model.
Cancer Chemotherapy and Pharmacology 1997, 40(3), 266-272.
- May FEB, Westley BR. Expression of human intestinal trefoil factor in malignant cells and its regulation by oestrogen in breast cancer cells.
Journal of Pathology 1997, 182(4), 404-413.
- Johnson LN, Barford D, Owen DJ, Noble MEM, Garman EF. From phosphorylase to phosphorylase kinase.
In: Signal Transduction in Health and Disease: 9th International Conference on Second Messengers and Phosphoproteins. 1997, Nashville, Tennessee, USA: Lippincott Williams and Wilkins.
- Chinnery PF, Shaw PJ, Ince PG, Jackson GH, Bishop RI. Fulminant encephalopathy due to the catastrophic primary antiphospholipid syndrome [15].
Journal of Neurology Neurosurgery and Psychiatry 1997, 62(3), 300-301.
- Polshakov V, Williams M, Gargaro A, Frenkiel T, Westley BR, Chadwick M, May FEB, Feeney J. High-resolution solution structure of human pNR-2/pS2: A single trefoil motif protein.
Journal of Molecular Biology 1997, 267(2), 418-432.
- Chadwick MP, Westley BR, May FEB. Homodimerization and hetero-oligomerization of the single-domain trefoil protein pNR-2/pS2 through cysteine 58.
Biochemical Journal 1997, 327, 117-123.
- Sinclair PB, Green AR, Grace C, Nacheva EP. Improved sensitivity of BCR-ABL detection: a triple-probe three colour fluorescence in situ hybridisation system.
Blood 1997, 90(4), 1395-1402.
- Clayton SJ, May FEB, Westley BR. Insulin-like growth factors control the regulation of oestrogen and progesterone receptor expression by oestrogens.
Molecular and Cellular Endocrinology 1997, 128(1-2), 57-68.
- Craft, A. W., Cotterill, S. J., Bullimore, J. A., Pearson, D. Long term results from the first UKCCSG Ewing's tumour study (ET-1).
European Journal of Cancer 1997, 33(7), 1061-1069.
- Boulton, S., Kyle, S., Durkacz, B.W. Low nicotinamide mononucleotide adenylyltransferase activity in a tiazofurin-resistant cell line: Effects on NAD metabolism and DNA repair.
British Journal of Cancer 1997, 76(7), 845-851.
- Boddy, A. V., Ratain, M. Pharmacogenetics in cancer etiology and chemotherapy.
Clinical Cancer Research 1997, 3(7), 1025-1030.
- Lawrie AM, Noble MEM, Tunnah P, Brown NR, Johnson LN, Endicott JA. Protein kinase inhibition by staurosporine revealed in details of the molecular interaction with CDK2.
Nature Structural Biology 1997, 4(10), 796-801.
- Souhami, R. L., Craft, A. W., VanderEijken, J. W., Nooij, M., Spooner, D., Bramwell, V. H. C., Wierzbicki, R., Malcolm, A. J., Kirkpatrick, A., Uscinska, B. M., VanGlabbeke, M., Machin, D. Randomised trial of two regimens of chemotherapy in operable osteosarcoma: a study of the European Osteosarcoma Intergroup.
The Lancet 1997, 350(9082), 911-917.
- Lovat PE, Irving H, Annicchiarico-Petruzzelli M, Bernassola F, Malcolm AJ, Pearson ADJ, Melino G, Redfern CPF. Retinoids in neuroblastoma therapy: Distinct biological properties of 9- cis- and all-trans-retinoic acid.
European Journal of Cancer 1997, 33(12), 2075-2080.
- Boddy AV, Thomas HD. RMP-7. Potential as an adjuvant to the drug treatment of brain tumours.
CNS Drugs 1997, 7(4), 257-263.
- Turner, R., Aherne, G., Curtin, N.J. Selective potentiation of lometrexol growth inhibition by dipyridamole through cell-specific inhibition of hypoxanthine salvage.
British Journal of Cancer 1997, 76(10), 1300-1307.
- Newlands ES, Stevens MFG, Wedge SR, Wheelhouse RT, Brock C. Temozolomide: a review of its discovery, chemical properties, pre-clinical development and clinical trials.
Cancer Treatment Reviews 1997, 23(1), 35-61.
- Lowe ED, Noble MEM, Skamnaki VT, Oikonomakos NG, Owen DJ, Johnson LN. The crystal structure of a phosphorylase kinase peptide substrate complex: kinase substrate recognition.
EMBO Journal 1997, 16(22), 6646-6658.
- Noble MEM, Endicott JA, Brown NR, Johnson LN. The cyclin box fold: protein recognition in cell-cycle and transcription control.
Trends in Biochemical Sciences 1997, 22(12), 482-487.
- Johnson LN, Brown NR, Endicott JA, Lawrie AM, Lowe ED, Noble MEM, Tunnah P. The structural basis for control by phosphorylation.
In: FASEB Journal. 1997, Federation of American Societies for Experimental Biology.
- Jackson, G. H., Taylor, P. R. A., Iqbal, A., Galloway, M. J., Turner, G., Haynes, A., Hamilton, P. J., Russell, N., Proctor, S. J. The use of an all oral chemotherapy (idarubicin and etoposide) in the treatment of acute myeloid leukaemia in the elderly: a report of toxicity and efficacy.
Leukemia 1997, 11(8), 1193-1196.
- May FEB, Westley BR. Trefoil proteins: Their role in normal and malignant cells.
Journal of Pathology 1997, 183(1), 4-7.