Newcastle University

Publications

Showing 10 Publications found in the The Northern Institute for Cancer Research, by Dr Barbara Durkacz.

• Veuger, S.J.; Curtin, N.J.; Smith, G.; Durkacz, B.W. Effects of novel inhibitors of poly(ADP-ribose) polymerase-1 and the DNA-dependent protein kinase on enzyme activities and DNA repair. Oncogene 2004, 23(44), 7322-7329.
• Willmore, E.; De Caux, S.; Sunter, N.; Tilby, M.J.; Jackson, G.; Austin, C.; Durkacz, B.W. A novel DNA-dependent protein kinase inhibitor, NU7026, potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia. Blood 2004, 103(12), 4659-4665.
• Calabrese C; Almassy R; Barton S; Batey M; Calvert AH; Canan-Koch S; Durkacz B; Hostomsky Z; Kumpf R; Kyle S; Li J; Maegley K; Newell DR; Notarianni E; Stratford I; Skalitzky D; Thomas HD; Wang L; Webber S; William K; Curtin NJ. Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361. Journal of the National Cancer Institute 2004, 96(1), 56-67.
• Calabrese C; Batey M; Thomas HD; Durkacz B; Wang L; Kyle S; Skalitzky D; Li J; Zhang C; Boritzki T; Maegley K; Calvert AH; Hostomsky Z; Newell DR; Curtin NJ. Identification of potent nontoxic poly(ADP-ribose) polymerase-1 inhibitors: Chemopotentiation and pharmacological studies. Clinical Cancer Research 2003, 9(7), 2711-2718.
• Veuger, S.; Curtin, N.J.; Richardson, C.; Smith, G.; Durkacz, B.W. Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1. Cancer Research 2003, 63(18), 6008-6015.
• Delaney, C.A.; Wang, L.; Kyle, S.; White, A.W.; Calvert, A.H.; Curtin, N.J.; Durkacz, B.W.; Hostomsky, Z; Newell, D.R. Potentiation of temozolomide and topotecan growth inhibition and cytotoxicity by novel poly(adenosine diphosphoribose) polymerase inhibitors in a panel of human tumor cell lines. Clinical Cancer Research 2000, 6(7), 2860-2867.
• Boulton SJ; Kyle S; Durkacz BW. Cytotoxic mechanism of the protein kinase inhibitor wortmannin in ionising radiation and etoposide treated cells. British Journal of Cancer 1999, 80(supplement 2), 44 P64.
• Boulton, S.; Kyle, S; Durkacz, B.W. Interactive effects of inhibitors of poly(ADP-ribose) polymerase and DNA-dependent protein kinase on cellular responses to DNA damage. Carcinogenesis 1999, 20(2), 199-203.
• Boulton, S.; Kyle, S.; Durkacz, B.W. Low nicotinamide mononucleotide adenylyltransferase activity in a tiazofurin-resistant cell line: Effects on NAD metabolism and DNA repair. British Journal of Cancer 1997, 76(7), 845-851.
• Boulton, S.; Kyle, S.; Yalçintepe, L.; Durkacz, B.W. Wortmannin is a potent inhibitor of DNA double strand break but not single strand break repair in Chinese hamster ovary cells. Carcinogenesis 1996, 17(11), 2285-2290.