Newcastle University

Roles and Responsibilities

Mycoplasma testing for the NICR

Qualifications

1999 MPhil, University of Newcastle upon Tyne

Previous Positions

1988-1999 Research Technician, Cancer Research Unit
1999 Research Associate, NICR

Memberships

BACR
AACR

Research Interests

Leukaemia
DNA repair mechanisms (predominantly mismatch repair)

Other Expertise

Drug resistance mechanisms

Current Work

Evaluation of the role of mismatch repair defects in relapse ALL.
Mechanisms of drug resistance in childhood acute lymphoblastic leukaemia.

• Nicholson L, Knight T, Matheson E, Minto L, Case M, Sanichar M, Bomken S, Vormoor J, Hall A, Irving J. Casitas B lymphoma mutations in childhood acute lymphoblastic leukemia. Genes, Chromosomes & Cancer 2012, 51(3), 250-256.
• Nicholson L, Evans C, Matheson EC, Minto L, Keilty C, Schwab C, Harrison CJ, Hall AG, Redfern C, Whetton A, Irving J. Quantitative Proteomic Analysis Reveals Maturation As a Mechanism Underlying Glucocorticoid Resistance in Childhood Acute Lymphoblastic Leukemia and PAX5 As a Re-Sensitising Therapeutic Target. In: Blood: 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH). 2011, San Diego, California, USA: American Society of Hematology.
• McInerney TL, Matheson E, Hall A. Drug discovery - High throughput automated 2-D gel analysis - Tutorial: Proteomic analysis with nonlinear dynamics' progenesis image analysis software. Genetic Engineering News 2001, 21(17), 32.