Newcastle University

Qualifications

2005 Membership of the Royal College of Paediatrics and Child Health, UK
2002 MBBS (Hons), Newcastle University
1999 BMedSci (Hons), Newcastle University

Memberships

Academic Paediatric Association GBI
British Association for Cancer Research
Children's Cancer & Leukaemia Group (CCLG)- Junior Member
European Haematology Association
Paediatric Oncology Trainees Group (CCLG)

Honours and Awards

Mona McNaughton Prize - MBBS (Hons) final examination results 2002
Wolfson Scholar - BMedSci (Hons) 1998/9

Research Interests

Childhood acute lymphoblastic leukaemia - characterisation of leukaemia stem cells

Current Work

Investigation of the biology underlying the self-renewal potential of leukaemia stem cells in childhood acute lymphoblastic leukaemia

Funding

MRC Clinical Research Training Fellowship
ACF post supported by National Institute for Health Research (NIHR)

• Sunter NJ, Scott K, Hills R, Grimwade D, Taylor S, Worrillow LJ, Fordham SE, Forster VJ, Jackson G, Bomken S, Jones G, Allan JM. A functional variant in the core promoter of the CD95 cell death receptor gene predicts prognosis in acute promyelocytic leukemia. Blood 2012, 119(1), 196-205.
• Nicholson L, Knight T, Matheson E, Minto L, Case M, Sanichar M, Bomken S, Vormoor J, Hall A, Irving J. Casitas B lymphoma mutations in childhood acute lymphoblastic leukemia. Genes, Chromosomes & Cancer 2012, 51(3), 250-256.
• Rehe K, Wilson K, Bomken S, Stanulla M, Heidenreich O, Vormoor J. In acute lymphoblastic leukaemia stemness is frequent and ubiquitous. In: Klinische Paediatrie: XXIV. Jahrestagung der Kind-Philipp-Stiftung für Leukämieforschung. 2011, Wilsede, Lüneburger Heide: Georg Thieme Verlag.
• Bomken S, Buechler L, Rehe K, Ponthan F, Blair H, Heidenreich O, Vormoor J. Lentiviral Transduction of Patient Derived Leukaemic Blasts Allowing In Vivo Bioluminescent Monitoring in An NSG Model of Leukaemia Stem Cell Maintenance. In: Blood: 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH). 2011, San Diego, California, USA: American Society of Hematology.
• Bomken S, Davies B, Chong L, Cole M, Wood KM, McDermott M, Tweddle DA. Percentage tumor necrosis following chemotherapy in neuroblastoma correlates with MYCN status but not survival. Pediatric Hematology & Oncology 2011, 28(2), 106-114.
• Sunter NJ, Scott K, Hills R, Grimwade D, Taylor S, Worillow L, Jackson G, Bomken S, Jones G, Allan JM. A Functional Polymorphism In the CD95 Cell Death Receptor Associated with Prognosis In Acute Promyelocytic Leukemia. In: 52nd Annual Meeting of the American Society of Hematology. 2010, Orlando, FL: Blood: American Society of Hematology.
• Sunter NJ, Scott K, Hills R, Grimwade D, Taylor S, Worrillow L, Jackson G, Bomken S, Jones G, Allan JM. A Functional Polymorphism In the CD95 Cell Death Receptor Associated with Prognosis In Acute Promyelocytic Leukemia. In: Blood: 52nd Annual Meeting of the American Society of Hematology. 2010, Orlando, Florida, USA: American Society of Hematology.
• Garrido Castro P, Bomken S, Seslija L, Stam R, Latif ES, Batey MA, McNeill H, Pieters R, Vormoor J, Greil J, Heidenreich O. ANGIOPOIETIN1 a Novel Factor Implicated In MLL Rearranged Acute Lymphoblastic Leukemia and Regulated In a Fusion Gene Dependent Manner. In: 52nd Annual Meeting of the American Society of Hematology. 2010, Orlando, FL: Blood: American Society of Hematology.
• Rehe K, Wilson K, Bomken S, McNeill H, Stanulla M, Den Boer ML, Irving J, Heidenreich O, Vormoor J. In Acute Lymphoblastic Leukaemia, Stemness Is Frequent and Ubiquitous. In: Blood: 52nd Annual Meeting of the American Society of Hematology. 2010, Orlando, Florida, USA: American Society of Hematology.
• Rehe K, Wilson K, Bomken S, McNeill H, Stanulla M, Den Boer ML, Irving J, Heidenreich O, Vormoor J. In Acute Lymphoblastic Leukaemia, Sternness Is Frequent and Ubiquitous. In: Blood: 52nd Annual Meeting of the American Society of Hematology. 2010, Orlando, Florida, USA: American Society of Hematology.
• le Viseur C, Hotfilder M, Bomken S, Wilson K, Röttgers S, Schrauder A, Rosemann A, Irving JAE, Stam R, Shultz L, Harbott J, Jürgens H, Schrappe M, Pieters R, Vormoor HJ. In Childhood Acute Lymphoblastic Leukemia, Blasts at Different Stages of Immunophenotypic Maturation Have Stem Cell Properties. Cancer Cell 2008, 14(1), 47-58.
• Wilson K, Rehe K, Bomken S, Case M, Shultz L, Irving J, Vormoor J. In Childhood ALL, Both Blasts with a CD20(-/Low) and a CD20(High) Immunophenotype, Have the Ability to Transfer the Leukemia Onto Immune-Deficient NOD/Scid Y-/- Mice. In: Blood: 50th Annual Meeting of the American Society of Hematology. 2008, San Francisco, California, USA: American Society of Hematology.
• Bomken, S.N., Redfern, K., Wood, K, Reid, M.M., Tweddle, D.A. Limitations in the ability of NB84 to detect metastatic neuroblastoma cells in bone marrow. Journal of Clinical Pathology 2006, 59(9), 927-929.