School of Medical Education

Staff Profile

Professor Danny McLaughlin

Professor

Background

I initially studied Physiology at the University of Glasgow, graduating in 1986. I stayed in the city to study for a PhD in Autonomic Pharmacology, before leaving to take up a postdoctoral position at the Institute of Psychiatry in London in 1990. I subsequently held postdoc positions at the Mental Health Research Institute of the University of Michigan (partly supported by an MRC Travelling Fellowship) and at the Institute of Ophthalmology in London, before being appointed Lecturer in Neuropharmacology at Bart’s and the London School of Medicine & Dentistry in 1998.

I left London in 2003 to help establish the Graduate Entry Medicine (GEM) course at the University of Nottingham. This was a major change in career direction, prompted by my growing interest in medical education theory and practice. From 2008-2014, I was Director of Undergraduate Studies at Nottingham, with responsibility for GEM, the Foundation Year for Medicine, and BSc Medical Physiology & Therapeutics programmes.

My teaching expertise is in physiology, neuroscience/neuroanatomy and pharmacology. In 2007, I was the major author of Instant Notes in Human Physiology and 2017 saw the publication of Clinical Chemistry. I received professional recognition as a Senior Fellow of the Higher Education Academy in 2013.

I have held external examiner positions on the medical degree programmes at the Royal College of Surgeons in Ireland (2006-2010 for undergraduate entry and 2011-2014 for graduate entry), the University of Birmingham (2007-2010, graduate entry), Bart’s and the London School of Medicine and Dentistry (2011-2014, undergraduate entry), and Swansea Medical School (2015-present, graduate entry).

My scholarly interests include the development of clinical reasoning skills in undergraduate medical students, the impact of widening participation initiatives in medical education and higher education in general, and novel methods for teaching medical students.  I am a member of the Board for the European Team-Based Learning Collaborative (ETBLC).


Authored books

White, D., Lawson, N., Masters, P. & McLaughlin D. (2017): Clinical Chemistry. New York: Garland Science.

McLaughlin, D. P., Stamford, J. & White, D. (2010). Insan Fizyolojisi. Nobel Yayin Dagitim.

McLaughlin, D. P., Stamford, J. & White, D. (2008). Krótkie wyklady Fizjologia czlowieka. Wydawnictwo Naukowe PWN.

McLaughlin, D.P., Stamford, J. A., White, D. A. & Bennett, T. (2007). BIOS Instant Notes in Human Physiology. New York: Taylor & Francis.


Journal Articles

McLaughlin, D. P., Tunstall, R., Garrud, P. & da Silva, A. (2010). Integrative Learning in the Medical Curriculum: Clinical Reasoning Assessments on the Graduate Entry Medicine Course. Centre for Integrative Learning 4: 96-106.

Pennington, J.M. Millar, J., Jones,C.P.L., Owesson, C.Å., McLaughlin, D.P. & Stamford, J.A. (2004). Simultaneous real-time amperometric measurement of catecholamines and serotonin at carbon fibre 'dident' microelectrodes. Journal of Neuroscience Methods 140(1-2): 5-13.

Tso, M. M, Blatchford, K. L, Callado, L. F, McLaughlin, D. P & Stamford, J. A. (2004). Stereoselective effects of ketamine on dopamine, serotonin and noradrenaline release and uptake in rat brain slices. Neurochemistry International 44(1): 1-7.

Owesson, C.Å., Seif, I., McLaughlin, D. P. & Stamford, J. A. (2003). Different alpha2-adrenoceptor subtypes control noradrenaline release and cell firing in the locus coeruleus of C3H/HeJ and monoamine oxidase-A knockout mice. European Journal of Neuroscience 18(1): 34-42.

Blatchford, K. L., McLaughlin, D. P. & Stamford, J. A. (2003). Ectopic serotonin accumulation and eeflux in rat mesencephalic slices after prior tissue 'radiolabelling'. Brain Research Bulletin 61(1): 57-62.

Owesson, C. Å. Hopwood, S. E. Callado, L. F., Seif, I., McLaughlin, D. P. & Stamford, J. A. (2002). Altered presynaptic function in monoaminergic neurons of monoamine oxidase-A knockout mice. European Journal of Neuroscience 15(9): 1516-1522.

Toner, C. C., Milne, A. J., Blatchford, K. L., McLaughlin, D. P. & Stamford, J. A. (2002). An assessment of the cerebroprotective potential of volatile anaesthetics using two independent methods in an in vitro model of cerebral ischaemia. Brain Research 958(2): 390-398.

Mathews, K. S., Toner, C. C., McLaughlin, D. P. & Stamford, J. A. (2001). Comparison of ketamine stereoisomers on brain metabolic activity in an in vitro ischaemia model. Neurochemistry International 38(5): 367-372.

Hopwood, S. E., Owesson, C. Å., Callado, L. F., McLaughlin, D. P. & Stamford, J. A. (2001). Effects of chronic tramadol on pre- and postsynaptic measures of monoamine function. Journal of Psychopharmacology 15(3): 147-153.

Toner, C. C., Connelly, K., Whelpton, R., Bains, S., Michael-Titus, A. T. McLaughlin, D. P. & Stamford, J. A. (2001). Effects of sevoflurane on dopamine, glutamate and aspartate release in an in vitro model of global cerebral ischaemia. British Journal of Anaesthesia 86(4): 550-554.

O’Neill, M. J., Hicks, C. A., Ward, M. A., Osborne, D. J., Wishart, G., Mathews, K. S., McLaughlin, D. P., Stamford, J. A., McCarty, D. R., Patrick, K. E., Roman, C. Fleisch, J. H., Gilmore, J. & Boot, J.R. (2001). LY393615, a novel neuronal Ca2+ and Na+ channel blocker with neuroprotective effects in models of in vitro and in vivo cerebral ischaemia. Brain Research 888(1): 138-149.

McLaughlin, D. P., Sharma, A., McGinley, A. & Samra, G. S. (2001). The advantages of haplotype analysis of the promoter region of the human apolipoprotein E gene. Analytical Biochemistry 299(2): 183-187.

Stamford, J. A., Davidson, C. McLaughlin, D. P. & Hopwood, S. E. (2000). Control of dorsal raphe 5-HT function by multiple 5-HT1 autoreceptors: parallel purposes or pointless plurality?. Trends in Neurosciences 23(10): 459-465.

Mathews, K. S., McLaughlin, D. P., Ziabari, L. H., Toner, C. C., Street, P. C., Hisgrove, E., Bezzina, E. L. & Stamford, J. A. (2000). Rapid quantification of ischaemic injury and cerebroprotection in brain slices using densitometric assessment of 2,3,5-triphenyltetrazolium chloride staining. Journal of Neuroscience Methods 102(1): 43-51.

Little, K. Y. McLaughlin, D. P., Zhang, L., McFinton, P. R., Dalack, G. W., Cook, E. H., Cassin, B. J. & Watson, S. J. (1998). Brain dopamine transporter messenger RNA and binding sites in cocaine users - A post mortem study. Archives of General Psychiatry 55(9): 793-99.

Little, K. Y., McLaughlin, D. P., Zhang, L., Livermore, C. S., Dalack, G. W., McFinton, P. R., DelProposto, Z. S., Hill, E. Cassin, B. J., Watson, S. J. & Cook, E. H. (1998). Cocaine, ethanol and genotype effects on human midbrain serotonin transporter binding sites and mRNA levels. American Journal of Psychiatry 155(2): 207-213.

Little, K. Y., McLaughlin, D. P., Ranc, J., Gilmore, J., López, J. F., Watson, S. J., Carroll, F. I. & Butts, J. D. (1997). Serotonin transporter binding sites and mRNA levels in depressed persons committing suicide. Biological Psychiatry 41(12): 1156-1164.

MacDonald, A., McLaughlin, D. P., MacDonald, E., Fulton, J. & Scott, P. J. W. (1996). Effects of catecholamines on isolated human colonic smooth muscle. Journal of Autonomic Pharmacology 16(4): 213-220.

McLaughlin, D. P., Little, K. Y., López, J. F. & Watson, S. J. (1996). Expression of serotonin transporter mRNA in human brainstem raphe nuclei. Neuropsychopharmacology 15(5): 523-529.

MacDonald, A., Forbes, I. J., Gallacher, D., Heeps, G. & McLaughlin, D.P. (1994). Adrenoceptors mediating relaxation to catecholamines in rat isolated jejunum. British Journal of Pharmacology 112(2): 576-578.

McLaughlin, D. P., Cheetham, M. E. & Kerwin, R. W. (1993). Expression of alternatively-spliced glutamate receptors in human hippocampus. European Journal of Pharmacology: Molecular Pharmacology 244(1): 89-92.

McLaughlin, D. P. & MacDonald, A. (1991). Characterisation of catecholamine-mediated relaxations in rat isolated gastric fundus - evidence for an atypical beta-adrenoceptor. British Journal of Pharmacology 103(2): 1351-1356.

Harrison, P. J., McLaughlin, D. & Kerwin, R. W. (1991). Decreased hippocampal expression of a glutamate receptor gene in schizophrenia. The Lancet 337(8739): 450-452.

McLaughlin, D. P., MacDonald, A., Fulton, J. D., MacDonald, E. & Scott, P. J. W. (1990). Ageing and responsiveness to catecholamines in human colonic circular smooth muscle. European Journal of Pharmacology 183: 1006-1007.

McLaughlin, D. P. & MacDonald, A. (1990). Evidence for the existence of 'atypical' beta-adrenoceptors (beta3-adrenoceptors) mediating relaxatory responses in the rat distal colon in vitro. British Journal of Pharmacology 101(3): 569-574.