Undergraduate

modules

Modules

ACE1013 : Introduction to Genetics

Semesters
Semester 1 Credit Value: 10
ECTS Credits: 5.0

Aims

To develop a basic understanding of genetic principles and their application in biology.
An introduction to the concepts and applications of genetics within the biological sciences.

Outline Of Syllabus

Introduction to the module: key elements of genetics

Mitosis and meiosis: Cell cycle and chromosome replication,
Recombination and segregation, the basis of variability.

Transmission (Mendelian) Genetics: Key concepts and vocabulary, Mendel's experimental approach, monohybrid and dihybrid crosses, Mendel's laws, deviations from complete dominance, gene interactions, polygenic traits, chromosome theory, X-linked traits, chromosomal anomalies, pedigree analysis.

Molecular genetics: Introduction to molecular genetics, DNA strucrure, Genomes, packaging of DNA, DNA replication.

DNA-RNA-Protein: The process of protein synthesis, transcription, structure of RNA, RNA processing in eukaryotes, Architecture of eukaryotic genes, functional importance of processing events.

Translation: Ribosome structure, RNA molecules, mechanism of protein synthesis.

Regulation of gene expression, Eukaryotic regulation.

Analytical techniques in molecular genetics, Polymerase Chain Reaction (PCR).

Recombinant DNA technology: Components of the technology and applications.

Teaching Methods

Teaching Activities
Category Activity Number Length Student Hours Comment
Guided Independent StudyAssessment preparation and completion15:005:00Preparation for practical report
Guided Independent StudyAssessment preparation and completion112:0012:00Revision and completion of Semester 1 examination
Scheduled Learning And Teaching ActivitiesLecture201:0020:00Introduce vocabulary of genetics and principles of cytogenetics, transmission and molecular genetics
Guided Independent StudyAssessment preparation and completion12:002:00Completion of Mock Section B examination (CAL)
Guided Independent StudyAssessment preparation and completion15:005:00Preparation for problem solving exercise
Scheduled Learning And Teaching ActivitiesPractical13:003:00Helps students to understand the concepts, techniques and methods of molecular genetics
Scheduled Learning And Teaching ActivitiesWorkshops13:003:00Allows students to apply their knowledge of transmission genetics by solving genetics problems
Guided Independent StudyIndependent study130:0030:00Background research and reading beyond the course material.
Guided Independent StudyIndependent study120:0020:00Writing up lecture, workshop and practical notes.
Total100:00
Teaching Rationale And Relationship

The lectures introduce the vocabulary of genetics and describe the principles and practices involved in cytogenetics, transmission genetics and molecular genetics. The workshop session encourages students to apply their knowledge of transmission genetics in solving genetics problems. The practical will help students to understand the concepts, techniques and methods of molecular genetics in greater detail by allowing them to complete practical tasks and watch demonstrations.

Assessment Methods

The format of resits will be determined by the Board of Examiners

Exams
Description Length Semester When Set Percentage Comment
Written Examination1201A70Exam is half done on paper and half on PC. True / False questions, Multiple choice questions, Essay/ Problem based questions
Other Assessment
Description Semester When Set Percentage Comment
Practical/lab report1M15Molecular genetics practical report, Week 11 (max 6 pages including graphs)
Prob solv exercises1M15Problem solving exercise, Set by Week 9
Formative Assessments
Description Semester When Set Comment
Written Examination1MMock section B examination (CAL)
Assessment Rationale And Relationship

Examination tests the knowledge and understanding of information delivered in the lectures, workshop and practical. The problem solving exercise assesses numeracy and the understanding of Mendelian genetics. The practical report assesses the skills of data collection, analysis and reporting.
Exam has 4 sections and each section carries equal marks
Section A - True / False questions (whole syllabus)
Section B – Multiple choice questions (Dr Tetard-Jones)
Section C - Essay/ Problem based questions, answer 1 from 2 (Dr Beard)
Section D - Essay based questions, answer 1 from 2 (Dr Tahar)
Exam is half done on paper and half on PC.

Reading Lists

Timetable