ACE1013 : Introduction to Genetics
- Offered for Year: 2017/18
- Module Leader(s): Dr Andrew Beard
- Other Staff: Dr Tahar Taybi, Dr Ankush Prashar
- Owning School: Natural and Environmental Sciences
- Teaching Location: Newcastle City Campus
|Semester 1 Credit Value:||10|
To develop a basic understanding of genetic principles and their application in biology.
An introduction to the concepts and applications of genetics within the biological sciences.
Outline Of Syllabus
Introduction to the module: key elements of genetics
Mitosis and meiosis: Cell cycle and chromosome replication,
Recombination and segregation, the basis of variability.
Transmission (Mendelian) Genetics: Key concepts and vocabulary, Mendel's experimental approach, monohybrid and dihybrid crosses, Mendel's laws, deviations from complete dominance, gene interactions, polygenic traits, chromosome theory, X-linked traits, chromosomal anomalies, pedigree analysis.
Molecular genetics: Introduction to molecular genetics, DNA strucrure, Genomes, packaging of DNA, DNA replication.
DNA-RNA-Protein: The process of protein synthesis, transcription, structure of RNA, RNA processing in eukaryotes, Architecture of eukaryotic genes, functional importance of processing events.
Translation: Ribosome structure, RNA molecules, mechanism of protein synthesis.
Regulation of gene expression, Eukaryotic regulation.
Analytical techniques in molecular genetics, Polymerase Chain Reaction (PCR).
Recombinant DNA technology: Components of the technology and applications.
|Guided Independent Study||Assessment preparation and completion||1||5:00||5:00||Preparation for problem solving exercise|
|Guided Independent Study||Assessment preparation and completion||1||5:00||5:00||Preparation for practical report|
|Guided Independent Study||Assessment preparation and completion||1||12:00||12:00||Revision and completion of Semester 1 examination|
|Scheduled Learning And Teaching Activities||Lecture||20||1:00||20:00||Introduce vocabulary of genetics and principles of cytogenetics, transmission and molecular genetics|
|Guided Independent Study||Assessment preparation and completion||1||2:00||2:00||Completion of Mock Section B examination (CAL)|
|Scheduled Learning And Teaching Activities||Practical||1||3:00||3:00||Helps students to understand the concepts, techniques and methods of molecular genetics|
|Scheduled Learning And Teaching Activities||Workshops||1||3:00||3:00||Allows students to apply their knowledge of transmission genetics by solving genetics problems|
|Guided Independent Study||Independent study||1||20:00||20:00||Writing up lecture, workshop and practical notes.|
|Guided Independent Study||Independent study||1||30:00||30:00||Background research and reading beyond the course material.|
Teaching Rationale And Relationship
The lectures introduce the vocabulary of genetics and describe the principles and practices involved in cytogenetics, transmission genetics and molecular genetics. The workshop session encourages students to apply their knowledge of transmission genetics in solving genetics problems. The practical will help students to understand the concepts, techniques and methods of molecular genetics in greater detail by allowing them to complete practical tasks and watch demonstrations.
The format of resits will be determined by the Board of Examiners
|Written Examination||120||1||A||70||Exam is half done on paper and half on PC. True / False questions, Multiple choice questions, Essay/ Problem based questions|
|Practical/lab report||1||M||15||Molecular genetics practical report, Week 11 (max 6 pages including graphs)|
|Prob solv exercises||1||M||15||Problem solving exercise, Set by Week 9|
|Written Examination||1||M||Mock section B examination (CAL)|
Assessment Rationale And Relationship
Examination tests the knowledge and understanding of information delivered in the lectures, workshop and practical. The problem solving exercise assesses numeracy and the understanding of Mendelian genetics. The practical report assesses the skills of data collection, analysis and reporting.
Exam has 4 sections and each section carries equal marks
Section A - True / False questions (whole syllabus)
Section B – Multiple choice questions (Dr Tetard-Jones)
Section C - Essay/ Problem based questions, answer 1 from 2 (Dr Beard)
Section D - Essay based questions, answer 1 from 2 (Dr Tahar)
Exam is half done on paper and half on PC.