BGM1004 : Genetics

Semester 1 Credit Value: 15
ECTS Credits: 8.0


The aims of this module include introducing the fundamental principles of Mendelian Genetics and addressing the field of Molecular Genetics. The course covers the areas of Bacterial, Eukaryote and Molecular, and Human Genetics, and should provide students with a general and conceptual understanding of genetics for their chosen degree. The ability to interpret genetic information and work through problems will be practised in seminars, and laboratory classes will enable data interpretation as well as providing essential practical skills.

The module will describe some of the molecular and genetic techniques being used in the post-genomic era of genetics. Fundamental genetic concepts and ideas will be discussed, as well as recent advances in genetic analysis including the use of model organisms. It will look at specific problems in human genetic diseases and their diagnosis and it will provide an introduction to the issues of health management and ethics. The material will consider cytogenetics, and how genes behave in populations.

Outline Of Syllabus

Lectures and seminars will cover the following topics:
Evolutionary genetics: prebiotic chemistry; ribozymes as molecular fossils; molecular phylogenetics and population genetics.
Molecular genetics: introduction to bacterial genetics; structure of the bacterial chromosome; comparative genomics; DNA replication and fidelity.
Eukaryote and Human Genetics: model eukaryotic organisms for genetic analysis; organization of eukaryotic genomes; mitosis and meiosis; sex determination, eukaryotic genes and transcripts; inheritance; recombination & genetic diversity; genome evolution & multigene families.
Developmental and Medical Genetics: genetic analysis of human disease; modern methods of mapping susceptibility alleles; yeast as a human disease model; clinical genetics of complex diseases; ethics in Genetics

Teaching Methods

Teaching Activities
Category Activity Number Length Student Hours Comment
Guided Independent StudyAssessment preparation and completion11:001:00Formative class tests
Scheduled Learning And Teaching ActivitiesLecture261:0026:00N/A
Scheduled Learning And Teaching ActivitiesSmall group teaching41:004:00Seminars
Scheduled Learning And Teaching ActivitiesDissertation/project related supervision11:001:00Oral Presentation
Guided Independent StudyIndependent study1118:00118:00N/A
Teaching Rationale And Relationship

1. Lectures will define the scope of the course and communciate basic knowledge as a basis for further study.
2. Seminars will encourage students to develop their understanding of the subject and interpersonal communication skills. They provide an opportunity for students to ask questions and exchange ideas in a small group setting. Skills practiced include critical thinking, numeracy, communication & team working.
3. Private study is used for self-directed learning and includes: reading lecture notes and texts; preparation for seminars; using learning resources on the Web. Skills practiced include critical thinking, active learning, numeracy, planning and organisation and independence.

Assessment Methods

The format of resits will be determined by the Board of Examiners

Description Length Semester When Set Percentage Comment
Written Examination901A100EMI format: 25-30 questions
Exam Pairings
Module Code Module Title Semester Comment
Formative Assessments
Description Semester When Set Comment
Computer assessment1MA mid-semester EMI (formative) 25-30 questions will be provided to students under exam conditions.
Assessment Rationale And Relationship

The end of semester examination assesses knowledge and understanding of the course material. The formative EMI questions will help students assess their knowledge and understanding of course material as well as familiarise students with the format of an EMI exam.

FMS Schools offering Semester One modules available as ‘Study Abroad’ will, where required, provide an alternative assessment time for examinations that take place after the Christmas vacation. Coursework with submissions dates after the Christmas vacation will either be submitted at an earlier date or at the same time remotely.

The form of assessment will not vary from the original.

Reading Lists