BGM1004 : Genetics
- Offered for Year: 2017/18
- Module Leader(s): Dr Catherine Meplan
- Lecturer: Prof. T. Martin Embley, Dr Jeremy Brown, Prof. Deborah Henderson, Prof. Colin Harwood, Dr Debra Bevitt, Prof. Brian Morgan, Prof. Sir John Burn, Dr Simon Whitehall
- Other Staff: Prof. David Lydall, Dr Simon Bamforth, Dr Carys Watts
- Owning School: Biomedical Sciences
- Teaching Location: Newcastle City Campus
|Semester 1 Credit Value:||15|
The aims of this module include introducing the fundamental principles of Mendelian Genetics and addressing the field of Molecular Genetics. The course covers the areas of Bacterial, Eukaryote and Molecular, and Human Genetics, and should provide students with a general and conceptual understanding of genetics for their chosen degree. The ability to interpret genetic information and work through problems will be practised in seminars, and laboratory classes will enable data interpretation as well as providing essential practical skills.
The module will describe some of the molecular and genetic techniques being used in the post-genomic era of genetics. Fundamental genetic concepts and ideas will be discussed, as well as recent advances in genetic analysis including the use of model organisms. It will look at specific problems in human genetic diseases and their diagnosis and it will provide an introduction to the issues of health management and ethics. The material will consider cytogenetics, and how genes behave in populations.
Outline Of Syllabus
Lectures and seminars will cover the following topics:
Evolutionary genetics: prebiotic chemistry; ribozymes as molecular fossils; molecular phylogenetics and population genetics.
Molecular genetics: introduction to bacterial genetics; structure of the bacterial chromosome; comparative genomics; DNA replication and fidelity.
Eukaryote and Human Genetics: model eukaryotic organisms for genetic analysis; organization of eukaryotic genomes; mitosis and meiosis; sex determination, eukaryotic genes and transcripts; inheritance; recombination & genetic diversity; genome evolution & multigene families.
Developmental and Medical Genetics: genetic analysis of human disease; modern methods of mapping susceptibility alleles; yeast as a human disease model; clinical genetics of complex diseases; ethics in Genetics
|Guided Independent Study||Assessment preparation and completion||1||1:00||1:00||Formative class tests|
|Scheduled Learning And Teaching Activities||Lecture||26||1:00||26:00||N/A|
|Scheduled Learning And Teaching Activities||Small group teaching||4||1:00||4:00||Seminars|
|Guided Independent Study||Independent study||1||118:00||118:00||N/A|
|Scheduled Learning And Teaching Activities||Dissertation/project related supervision||1||1:00||1:00||Oral Presentation|
Teaching Rationale And Relationship
1. Lectures will define the scope of the course and communciate basic knowledge as a basis for further study.
2. Seminars will encourage students to develop their understanding of the subject and interpersonal communication skills. They provide an opportunity for students to ask questions and exchange ideas in a small group setting. Skills practiced include critical thinking, numeracy, communication & team working.
3. Private study is used for self-directed learning and includes: reading lecture notes and texts; preparation for seminars; using learning resources on the Web. Skills practiced include critical thinking, active learning, numeracy, planning and organisation and independence.
The format of resits will be determined by the Board of Examiners
|Written Examination||90||1||A||100||EMI format: 25-30 questions|
|Module Code||Module Title||Semester||Comment|
|Computer assessment||1||M||A mid-semester EMI (formative) 25-30 questions will be provided to students under exam conditions.|
Assessment Rationale And Relationship
The end of semester examination assesses knowledge and understanding of the course material. The formative EMI questions will help students assess their knowledge and understanding of course material as well as familiarise students with the format of an EMI exam.
FMS Schools offering Semester One modules available as ‘Study Abroad’ will, where required, provide an alternative assessment time for examinations that take place after the Christmas vacation. Coursework with submissions dates after the Christmas vacation will either be submitted at an earlier date or at the same time remotely.
The form of assessment will not vary from the original.
- Reading List Website : rlo.ncl.ac.uk