CHY3103 : Chemotherapy

  • Module Leader(s): Dr Celine Cano
  • Owning School:
Semester 2 Credit Value: 10
ECTS Credits: 5.0


To introduce the basic concepts of the aetiology of cancer and pathogenic disease; to impart an understanding of the host-pathogen relationship, and the concepts of selective toxicity and resistance; to equip students with an understanding of the basic principles of chemotherapy of cancer and infectious disease; to provide an understanding of the molecular mechanisms underpinning the action of anticancer and anti-infective drugs

Outline Of Syllabus

Cancer Chemotherapy
Dr C Cano

1 Introduction to cancer
2 DNA reactive drugs
3 Antimetabolites
4 DNA Topoisomerase inhibitors
5 Mitotic poisons
6 DNA Repair Enzymes
7 Antiendocrine drugs
8 Current approaches to cancer chemotherapy
9 New thearapies: Targetting receptor tyrosine kinase signalling
10 Kinase inhibitors case studies

Chemotherapy of Infectious Diseases
Professor RJ Griffin

1 Introduction and historical overview
2 Principles of antimicrobial chemotherapy
3 Antibacterial agents – Penicillin and related ?-lactam
4 Antibacterial agents – Glycopeptides, quinolones, and oxazolidinones
5 Antifungal agents – Polyenes and azoles
6 Antifungal agents – Azoles and other antifungals
7 Metronidazole
8 Malaria and its treatment
9 Antiviral chemotherapy
10 Acyclovir and maraviroc

Teaching Methods

Teaching Activities
Category Activity Number Length Student Hours Comment
Guided Independent StudyAssessment preparation and completion161:2061:20Background reading and practice past paper examination questions
Guided Independent StudyAssessment preparation and completion200:5016:40Revision of end of semester examination
Guided Independent StudyAssessment preparation and completion12:002:00End of semester examination
Scheduled Learning And Teaching ActivitiesLecture201:0020:00N/A
Jointly Taught With
Code Title
CHY3109Advanced Medicinal Chemistry
CHY8823Theory and Practice of Chemotherapy
Teaching Rationale And Relationship

Students acquire an understanding of the subject through attendance and participation in lectures. An understanding of the topics is reinforced by problem solving, and critical background reading of the scientific literature.

Assessment Methods

The format of resits will be determined by the Board of Examiners

Description Length Semester When Set Percentage Comment
Written Examination1202A100N/A
Exam Pairings
Module Code Module Title Semester Comment
CHY3109Advanced Medicinal Chemistry2N/A
CHY8823Theory and Practice of Chemotherapy2N/A
Assessment Rationale And Relationship

The examination will assess the student's knowledge and understanding of the basic principles of the subject.

Reading Lists


Disclaimer: The University will use all reasonable endeavours to deliver modules in accordance with the descriptions set out in this catalogue. Every effort has been made to ensure the accuracy of the information, however, the University reserves the right to introduce changes to the information given including the addition, withdrawal or restructuring of modules if it considers such action to be necessary.