Staff Profile - Biomedical, Nutritional and Sport Sciences

Professor Farhad Kamali

Prof of Human & Exp Pharm

Email: farhad.kamali@ncl.ac.uk
Telephone: +44 (0) 191 208 8043
Address: Translational & Clinical Research Institute
4th Floor William Leech Building
Framlington Place
Medical School
Newcastle University
NE2 4HH

There is an increasing focus on translational research that directly impacts biomedical research, involving new and existing medicines, spanning from basic research (molecular and cellular) to clinical research which embody the ‘bench to bedside’ research. I have an international standing in my field of research with over 30 years of experience in pharmacology/clinical pharmacology/ experimental therapeutics, clinical trials and qualitative research. As such I have a good insight of the issues relating to study design and methodology, ethics, clinical governance and good clinical practice which concern pre-clinical and clinical/applied health research.

My research is multidisciplinary and at the basic-clinical phase in drug development and drug safety evaluation using novel and innovative approaches. I have a particularly keen interest in the treatment and prevention of thromboembolic disease. My research in the anticoagulation field aims to elucidate risks and benefits of anticoagulation and to achieve appropriate clinical strategies for prevention and treatment of thromboembolic disease using a whole system research approach. This ranges from the use of in vitro models in evaluating cellular and sub-cellular mechanisms by which drugs exert their pharmacological activity, to determining the contribution of dietary status, genetic polymorphisms of drug metabolism and pharmacodynamics, contribution of health related quality of life issues to appropriateness of anticoagulation and the impact of patient education about therapy and patient self-management of anticoagulation control in reducing thromboembolism and bleeding.

I run projects in collaboration with groups at local, national and international level, with the latter including being the Lead for Thrombosis and Anticoagulation Research Group at Newcastle University, and being one of the founding members of the International Warfarin Pharmacogenetics Consortium (IWPC) and the European Pharmacogenomics of Anticoagulation Therapy consortium (EU-PACT); Chairing the Trial Management Committee for EU-PACT.

In 2005 I was elected to Fellowship of the British Pharmacological Society in recognition of my commitment to and distinction in pharmacology through scholarship and service to the Society.

I have served and continue to serve on several committees with a diverse remit. Additionally over the years I have acted in an advisory capacity for the pharmaceutical industry. Through these experiences I have developed the skills to critically appraise new information and to make appropriate decisions and recommendations.

I serve on the editorial board of several international scientific journals. My responsibilities entail examining issues relating to manuscript submissions, manuscript and reviewer feedback appraisal, author feedback and the general review of the individual journal performance.