Institute for Cell and Molecular Biosciences

Staff Profile

Professor Janet Quinn

Professor of Eukaryotic Microbiology

Background

Education

1987-1990     BSc Hons Class I, Biochemistry, University of Wales

1990-1993     PhD, Newcastle University. Supervisor Prof Steve Yeaman.

 

Appointments

1994-1995    Postdoctoral Fellow,University of Massachusetts Medical Centre, USA, advisor Prof Craig Peterson

                                                               

1995-1998    Leukaemia Society of America Fellow, Newcastle University 


1998-2000    Postdoctoral Fellow Newcastle University, advisor Prof Brian Morgan

 

2000-2004    MRC Career Development Fellow Newcastle University 

           

2004-2008    Lecturer, Institute for Cell and Molecular Biosciences, Newcastle University

 

2008-2014    Reader in Molecular Biology, Institute for Cell and Molecular Biosciences, Newcastle University

 

2014-            Professor of Eukaryotic Microbiology, Institute for Cell and Molecular Biosciences, Newcastle University

Google Scholar: Click here.

Research

Research Interests

My laboratory’s primary research focus is on stress-sensing and signalling mechanisms in human pathogenic fungi and their importance in virulence. We study a range of pathogenic Candida spp. including Candida albicans, Candida glabrata and Candida auris. In particular we are interested in the role of the evolutionarily conserved stress-activated MAPK pathways in promoting fungal virulence, and the diverse mechanisms employed by fungal pathogens to survive  the toxic reactive oxygen species generated by innate immune cells.  Recently, we have also become interested in phosphate acquisition strategies within C. albicans due to our recent findings linking phosphate homeostasis and stress resistance. We are also exploiting our knowledge of fungal stress signalling and nutrient acquisition pathways to design and perform high throughput screens for compounds that inhibit these vital virulence traits. Please see publications tab for our recent publications.

Informal enquiries from prospective graduate students and post-docs are welcome at any time.

 

Current Funding

Wellcome Trust Strategic Award in Medical Mycology and Fungal Immunology

https://www.abdn.ac.uk/mmfi/

BBSRC Project Grants

https://bbsrc.ukri.org/research/grants-search/AwardDetails/?FundingReference=BB%2fP020119%2f1

 

Current Lab Members

Dr Alison Day (BBSRC funded)

Dr Katharina Trunk (Faculty funded)

Ms Yasmin Ahmed (BBSRC-DTP student)

Ms Michelle Wray (Technician, partially BBSRC funded)

 

Recent Public Engagement Activities

Newcastle Pint of Science 2018

https://pintofscience.co.uk/event/the-world-of-microbes-and-fungi


Newcastle Soapbox Science 2017

Soapbox Science highlights video:  http://www.voicenorth.org/news-blogs/2017/august/soapbox-science-newcastle-2017-highlights-video/

Soapbox Science Newcastle 2017 – Meet the Scientists: https://vimeo.com/233902250


Royal Society Summer Exhibition 2016 – Killer Fungus!

https://royalsociety.org/science-events-and-lectures/2016/summer-science-exhibition/exhibits/killer-fungus/

https://www.youtube.com/watch?v=Kupt17rbaIA

 



Teaching

BGM2002 - Biochemistry and Genetics of Signalling and the Cell Cycle

BMS3007- Research in Biomedical Sciences

MIC3046- Microbiota and Pathogens: Mucosal Microbiota, Protozoa and Fungi

Publications