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Staff Profile
Dr Ed Schwalbe
Guest Status
Publications
- Schwalbe EC, Hicks D, Rafiee G, Bashton M, Gohlke H, Enshaei A, Potluri S, Matthiesen J, Mather M, Taleongpong P, Chaston R, Silmon A, Curtis A, Lindsey JC, Crosier S, Smith AJ, Goschzik T, Doz F, Rutkowski S, Lannering B, Pietsch T, Bailey S, Williamson D, Clifford SC. Minimal methylation classifier (MIMIC): A novel method for derivation and rapid diagnostic detection of disease-associated DNA methylation signatures. Scientific Reports 2017, 7, 13421.
- Schwalbe EC, Lindsey JC, Nakjang S, Crosier S, Smith AJ, Hicks D, Rafiee G, Hill RM, Iliasova A, Stone T, Pizer B, Michalski A, Joshi A, Wharton SB, Jacques TS, Bailey S, Williamson D, Clifford SC. Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study. The Lancet Oncology 2017, 18(7), 958-971.
- Young GR, Smith DL, Embleton ND, Berrington JE, Schwalbe EC, Cummings SP, van der Gast CJ, Lanyon C. Reducing Viability Bias in Analysis of Gut Microbiota in Preterm Infants at Risk of NEC and Sepsis. Frontiers in Cellular and Infection Microbiology 2017, 7, 237.
- Crosier S, Hicks D, Schwalbe E, Williamson D, Nicholson S, Michalski A, Pizer B, Bailey S, Bown N, Robson K, Wharton S, Jacques T, Clifford S. Centralised Molecular Pathology for Rare Tumours: A National Feasibility Study of Real-Time Medulloblastoma Diagnostics. In: 17th International Symposium on Pediatric Neuro-Oncology (ISPNO). 2016, Liverpool, UK: Oxford University Press.
- Williamson D, Lindsey JC, Hicks D, Crosier S, Smith A, Bashton M, Hill R, Joshi A, Jacques TS, Schwalbe EC, Bailey S, Clifford SC. The Transcriptional Landscape of Medulloblastoma: Group 3 and Group 4 Tumours Comprise a Single Clinically Significant Expression Continuum. In: 17th International Symposium on Pediatric Neuro-Oncology (ISPNO). 2016, Liverpool, UK: Oxford University Press.
- Molyneux E, Schwalbe E, Chagaluka G, Banda K, Israels T, Depani S, Mittermayer-Vassallo K, Windebank K, Mvula J, Njiram'madzi J, O'Brien S, Carey P, Bailey S. The use of anthracyclines in the treatment of endemic Burkitt lymphoma. British Journal of Haematology 2017, 177(6), 984-990.
- Clifford SC, Lannering B, Schwalbe EC, Hicks D, O'Toole K, Nicholson SL, Goschzik T, Zur-Mühlen A, Figarella-Branger D, Doz F, Rutkowski S, Gustafsson G, Pietsch T. Biomarker-driven stratification of disease-risk in non-metastatic medulloblastoma: Results from the multi-center HIT-SIOP-PNET4 clinical trial. Oncotarget 2015, 6(36), 38827-38839.
- Hill RM, Kuijper S, Lindsey JC, Petrie K, Schwalbe EC, Barker K, Boult JKR, Williamson D, Ahmad Z, Hallsworth A, Ryan SL, Poon E, Robinson SP, Ruddle R, Raynaud FI, Howell L, Kwok C, Joshi A, Nicholson SL, Crosier S, Ellison DW, Wharton SB, Robson K, Michalski A, Hargrave D, Jacques TS, Pizer B, Bailey S, Swartling FJ, Weiss WA, Chesler L, Clifford SC. Combined MYC and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease. Cancer Cell 2015, 27(1), 72-84.
- Sheer D, Jeyapalan J, Doctor GT, Jones TA, Alberman SN, Tep A, Haria CM, Schwalbe EC, Clifford SC, Tatevossian RG, Qaddoumi I, Ellison DW. DNA Methylation Analysis of Paediatric Low-Grade Astrocytomas Identifies a Tumour-Specific Signature at a Set of Enhancers. In: 47th Congress of the International Society of Paediatric Oncology (SIOP). 2015, Cape Town, South Africa: Wiley-Blackwell.
- Molyneux E, Schwalbe E, Chagaluka G, Banda K, Israels T, Depani S, Mittermayer-Vassallo K, Windebank K, Mvula J, Njiram'nadzi J, Carey P, Bailey S. The Role of Anthracyclines in the Treatment of Endemic Burkitt Lymphoma. In: 47th Congress of the International Society of Paediatric Oncology (SIOP). 2015, Cape Town, South Africa: John Wiley & Sons, Inc.
- Molyneux EM, Kawaza K, Phiri A, Chimalizeni Y, Mankhambo L, Schwalbe EC, Kataja M, Pencilo P, Chilton L, Peltola H. Glycerol and acetaminophen as adjuvant therapy did not affect the outcome of bacterial meningitis in Malawian children. The Pediatric Infectious Disease Journal 2014, 33(2), 214-216.
- Lafta F, Rand V, Moorman A, Mitchell C, Kinsey S, Vora A, Cockell S, Schwalbel E, Enshaei A, Strathdee G. Investigation of methylation based biomarkers for prediction of relapse in good prognostic cytogenetic subgroups of childhood acute lymphoblastic leukaemia. In: 10th NCRI Cancer Conference. 2014, Liverpool, UK.
- Schwalbe EC, Williamson D, Lindsey JC, Hamilton D, Ryan SL, Megahed H, Garami M, Hauser P, Dembowska-Baginska B, Perek D, Northcott PA, Taylor MD, Taylor RE, Ellison DW, Bailey S, Clifford SC. DNA methylation profiling of medulloblastoma allows robust subclassification and improved outcome prediction using formalin-fixed biopsies. Acta Neuropathologica 2013, 125(3), 359-371.
- Zhukova N, Ramaswamy V, Remke M, Pfaff E, Shih DJ, Martin DC, Castelo-Branco P, Baskin B, Ray PN, Bouffet E, von-Bueren AO, Jones DT, Northcott PA, Kool M, Sturm D, Pugh TJ, Pomeroy SL, Cho YJ, Pietsch T, Gessi M, Rutkowski S, Bognar L, Klekner A, Cho BK, Kim SK, Wang KC, Eberhart CG, Fevre-Montange M, Fouladi M, French PJ, Kros M, Grajkowska WA, Gupta N, Weiss WA, Hauser P, Jabado N, Jouvet A, Jung S, Kumabe T, Lach B, Leonard JR, Rubin JB, Liau LM, Massimi L, Pollack IF, Shin-Ra Y, Van-Meir EG, Zitterbart K, Schüller U, Hill RM, Lindsey JC, Schwalbe EC, Bailey S, Ellison DW, Hawkins C, Malkin D, Clifford SC, Korshunov A, Pfister S, Taylor MD, Tabori U. Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma. Journal of Clinical Oncology 2013, 31(23), 2927-2935.
- Ryan SL, Schwalbe EC, Cole M, Lu Y, Lusher ME, Megahed H, O'Toole K, Nicholson SL, Bognar L, Garami M, Hauser P, Korshunov A, Pfister SM, Williamson D, Taylor RE, Ellison DW, Bailey S, Clifford SC. MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma. Acta Neuropathologica 2012, 123(4), 501-513.
- Menghi F, Jacques TS, Barenco M, Schwalbe EC, Clifford SC, Hubank M, Ham J. Genome-Wide Analysis of Alternative Splicing in Medulloblastoma Identifies Splicing Patterns Characteristic of Normal Cerebellar Development. Cancer Research 2011, 71(6), 2045-2055.