Centre for Bacterial Cell Biology

Staff Profile

Dr Elisabeth Lowe

Newcastle University Research Fellow

Research

My lab is interested in how the gut microbiota use the complex glycans available to them within the human gut, focussing on the Bacteroidetes. We are particularly interested in glycoside hydrolase enzymes that target the glycans of pathogens such as Mycobacterium tuberculosis and Candida albicans. We use a combination of microbiology, biochemistry, glycobiology and structural biology to understand the activity and function of these enzymes. We are also interested in the mechanisms of how Bacteroides sense and respond to the glycans they encounter using unusual hybrid two-component systems, and how they use the Type 9 Secretion System to enable extracellular glycan degradation.

Current lab members:

Dr Jennifer Ross

Omar Al-Jourani (PhD Student)

Diana Githwe (PhD student)

Joe Manion (PhD student)


Google Scholar profile

Teaching

CMB1003 - Microbiology and Immunology

BMS2015 - Health and Disease at Mucosal Surfaces

MMB8048 - Human Health and the Impact of Microbial Genomics

Publications