Publications

2020/21

2019/20

2018/19

Abohelaika S., Wynne H., Avery P., Kampouraki E., Kamali F. Effect of genetic and patient factors on warfarin pharmacodynamics following warfarin withdrawal: Implications for patients undergoing surgery. Thrombosis Research. 2018; 171 167-170 DOI: 10.1016/j.thromres.2018.09.064

Ahmed Z., Preshaw P.M., Bauld L., Holliday R. Dental professionals’ opinions and knowledge of smoking cessation and electronic cigarettes: A cross-sectional survey in the north of England. British Dental Journal. 2018; 225:10 DOI: 10.1038/sj.bdj.2018.1026

Allen S.F., Elder G.J., Longstaff L.F., Gotts Z.M., Sharman R. et al. Exploration of potential objective and subjective daily indicators of sleep health in normal sleepers. Nature and Science of Sleep. 2018; 10 303-312 DOI: 10.2147/NSS.S168841

Alston C.L., Heidler J., Dibley M.G., Kremer L.S., Taylor L.S. et al. incl. McFarland R. Bi-allelic Mutations in NDUFA6 Establish Its Role in Early-Onset Isolated Mitochondrial Complex I Deficiency. American Journal of Human Genetics. 2018; 103:4 592-601  DOI: 10.1016/j.ajhg.2018.08.013

Anstee Q.M., Mantovani A., Tilg H., Targher G. Risk of cardiomyopathy and cardiac arrhythmias in patients with nonalcoholic fatty liver disease. Nature Reviews Gastroenterology and Hepatology. 2018; 1-15 DOI: 10.1038/s41575-018-0010-0.

Aspray T.J., Chadwick T., Francis R.M., McColl E., Stamp E. et al. Randomized controlled trial of vitamin D supplementation in older people to optimize bone health. The American journal of clinical nutrition. 2019; 109:1 207-217 DOI: 10.1093/ajcn/nqy280

Bansagi B., Phan V., Baker M.R., O'Sullivan J., Jennings M.J. et al. incl. Horvath R. Multifocal demyelinating motor neuropathy and hamartoma syndrome associated with a de novo PTEN mutation. Neurology. 2018; 90:21 e1842-e1848 DOI: 10.1212/WNL.0000000000005566

Bartsakoulia M., Pyle A., Troncoso-Chandía D., Vial-Brizzi J., Paz-Fiblas M.V. et al. incl. Lochmüller H. A novel mechanism causing imbalance of mitochondrial fusion and fission in human myopathies. Human Molecular Genetics. 2018; 27:7 1186-1195 DOI: 10.1093/hmg/ddy033

Basu A.P., Pearse J., Watson R., Dulson P., Baggaley J. et.al. incl. Embleton N. Feasibility trial of an early therapy in perinatal stroke (eTIPS). BMC Neurology. 2018; 18:1 102 DOI: 10.1186/s12883-018-1106-4

Bate J., Baker S., Breuer J., Chisholm J.C., Gray J. et al. incl. Skinner R. PEPtalk2: Results of a pilot randomised controlled trial to compare VZIG and aciclovir as postexposure prophylaxis (PEP) against chickenpox in children with cancer. Archives of Disease in Childhood. 2018; DOI: 10.1136/archdischild-2017-314212

Batty J., Qiu W., Gu S., Sinclair H., Veerasamy M. et al incl. Kunadian V., ICON-1 Study Investigators. One-year clinical outcomes in older patients with non-ST elevation acute coronary syndrome undergoing coronary angiography: An analysis of the ICON1 study. International Journal of Cardiology. 2018; DOI: 10.1016/j.ijcard.2018.09.086

Beltran-Valls M.R., Janssen X., Farooq A., Adamson A.J., Pearce M.S. et al. Longitudinal changes in vigorous intensity physical activity from childhood to adolescence: Gateshead Millennium Study. Journal of Science and Medicine in Sport. 2018; DOI: 10.1016/j.jsams.2018.10.010

Bertoli M., Cereatti A., Trojaniello D., Avanzino L., Pelosin E., Del Din S. et al. incl Rochester L. Estimation of spatio-temporal parameters of gait from magneto-inertial measurement units: Multicenter validation among Parkinson, mildly cognitively impaired and healthy older adults. BioMedical Engineering Online. 2018; 17:1 58 DOI: 10.1186/s12938-018-0488-2

Birch J., Sunny S.S., Hester K.L.M., Parry G., Kate Gould F. et al. incl. Corris P.A. Outcomes of lung transplantation in adults with bronchiectasis. BMC Pulmonary Medicine. 2018; 18:1 82 DOI: 10.1186/s12890-018-0634-4

Bissett S.M., Presseau J., Rapley T., Preshaw P.M. Uptake of best practice recommendations in the management of patients with diabetes and periodontitis: A cross-sectional survey of dental clinicians British Dental Journal. 2019; 226:2 131-137 DOI: 10.1038/sj.bdj.2019.48

Blagojevic-Bucknall M., Mallen C., Muller S., Hayward R., West S. et al. The Risk of Gout Among Patients With Sleep Apnea: A Matched Cohort Study. Arthritis and Rheumatology. 2019; 71:1 154-160. DOI: 10.1002/art.40662

Bourke J.P., Watson G., Muntoni F., Spinty S., Roper H. et al. incl. Bushby K. Randomised placebo-controlled trial of combination ACE inhibitor and beta-blocker therapy to prevent cardiomyopathy in children with Duchenne muscular dystrophy? (DMD Heart Protection Study): A protocol study. BMJ Open. 2018; 8:12 e022572. DOI: 10.1136/bmjopen-2018-022572

Brown A.E., Dibnah B., Fisher E., Newton J.L., Walker M. Pharmacological activation of AMPK and glucose uptake in cultured human skeletal muscle cells from patients with ME/CFS. Bioscience Reports. 2018; 38:3  BSR20180242 DOI: 10.1042/BSR20180242

Buckley C., Alcock L., McArdle R., Ur Rehman R.Z., Del Din S. et al. incl. Yarnall A.J. The role of movement analysis in diagnosing and monitoring neurodegenerative conditions: Insights from gait and postural control. Brain Sciences. 2019; 9:2 DOI: 10.3390/brainsci9020034

Buckley C., Galna B., Rochester L., Mazzà C. Upper body accelerations as a biomarker of gait impairment in the early stages of Parkinson's disease. Gait and Posture. 2018; DOI: 10.1016/j.gaitpost.2018.06.166

Bugiardini E., Morrow J.M., Shah S., Wood C.L., Lynch D.S. et al. incl. Straub V. The diagnostic value of MRI pattern recognition in distal myopathies. Frontiers in Neurology. 2018; 9:JUN 456 DOI: 10.3389/fneur.2018.00456

Cassidy S., Fuller H., Chau J., Catt M., Bauman A., Trenell M.I. Accelerometer-derived physical activity in those with cardio-metabolic disease compared to healthy adults: a UK Biobank study of 52,556 participants. Acta Diabetologica. 2018; 1-5 DOI: 10.1007/s00592-018-1161-8

Cassidy S., Vaidya V., Houghton D., Zalewski P., Seferovic J.P. et al. incl Jakovljevic D.G. Unsupervised high-intensity interval training improves glycaemic control but not cardiovascular autonomic function in type 2 diabetes patients: A randomised controlled trial. Diabetes and Vascular Disease Research. 2018; DOI: 10.1177/1479164118816223

Chan F., Lax N.Z., Voss C.M., Aldana B.I., Whyte S. et al. incl. Turnbull D.M. The role of astrocytes in seizure generation: insights from a novel in vitro seizure model based on mitochondrial dysfunction. Brain : a journal of neurology. 2019; 142:2 391-411 DOI: 10.1093/brain/awy320

Chinnery P.F., Gomez-Duran A. Oldies but goldies mtDNA population variants and neurodegenerative diseases. Frontiers in Neuroscience. 2018; 12: OCT 682 DOI: 10.3389/fnins.2018.00682

Chivers Seymour K., Pickering R., Rochester L., Roberts H.C., Ballinger C. et al. Multicentre, randomised controlled trial of PDSAFE, a physiotherapist-delivered fall prevention programme for people with Parkinson's. Journal of Neurology, Neurosurgery and Psychiatry. 2019; DOI: 10.1136/jnnp-2018-319448

Chua S.Y.L., Thomas D., Allen N., Lotery A., Desai P. et al. incl. Steel D. Cohort profile: Design and methods in the eye and vision consortium of UK Biobank. BMJ Open. 2019; 9:2 e025077 DOI: 10.1136/bmjopen-2018-025077

Codd A., Burford B., Petruso G., Davidson N., Vance G. Development and evaluation of a digistory about autistic spectrum disorder – a pilot study. Education for Primary Care. 2018;1-5 DOI: 10.1080/14739879.2018.1470906

Colver A., McConachie H., Le Couteur A., Dovey-Pearce G., Mann K.D. et al. incl. Pearce M.S. A longitudinal, observational study of the features of transitional healthcare associated with better outcomes for young people with long-term conditions. BMC Medicine. 2018; 16:1 111 DOI: 10.1186/s12916-018-1102-y

Cooles F.A.H., Anderson A.E., Skelton A., Pratt A.G., Kurowska-Stolarska M.S. et al. incl. Isaacs J.D. Phenotypic and transcriptomic analysis of peripheral blood plasmacytoid and conventional dendritic cells in early drug naïve rheumatoid arthritis. Frontiers in Immunology. 2018; 9(MAY) 795 DOI: 10.3389/fimmu.2018.00755

Crosbie E.J., Ryan N.A.J., Arends M.J., Bosse T., Burn J. et al. Manchester International Consensus Group. The Manchester International Consensus Group recommendations for the management of gynaecological cancers in Lynch syndrome. Genetics in Medicine.2019; DOI:  10.1038/s41436-019-0489-y

Da-Silva R.H., Moore S.A., Price C.I. Self-directed therapy programmes for arm rehabilitation after stroke: a systematic review. Clinical Rehabilitation. 2018; DOI: 10.1177/0269215518775170

daSilva Morgan K., Elder G.J., ffytche D.H., Collerton D., Taylor J.-P. The utility and application of electrophysiological methods in the study of visual hallucinations. Clinical Neurophysiology. 2018; 129:11 2361-2371 DOI: 10.1016/j.clinph.2018.08.019

Da Silva R., Rodgers H., Shaw L., van Wijck F., Moore S.A. et al. Wristband accelerometers to motivate arm exercise after stroke (WAVES): Activity data from a pilot randomised controlled trial. Annals of Physical and Rehabilitation Medicine. 2018; DOI: 10.1016/j.rehab.2018.05.067

Dand N., Duckworth M., Baudry D., Russell A., Curtis C.J. et al. incl. Reynolds N.J. BADBIR Study Group, BSTOP Study Group, The members of the PSORT consortium . HLA-C*06:02 genotype is a predictive biomarker of biologic treatment response in psoriasis. Journal of Allergy and Clinical Immunology. 2019; DOI: 10.1016/j.jaci.2018.11.038

Dew R., King K., Okosieme O.E., Pearce S.H., Donovan G. et al. incl. Razvi S. Attitudes and perceptions of health professionals towards management of hypothyroidism in general practice: A qualitative interview study. BMJ Open. 8:2 e019970 DOI: 10.1136/bmjopen-2017-019970

Dhar A., Sadiq F., Anstee Q.M., Levene A.P., Goldin R.D., Thursz M.R. Thrombin and factor Xa link the coagulation system with liver fibrosis. BMC Gastroenterology. 18:1 60 DOI: 10.1186/s12876-018-0789-8

Dodds R.M., Davies K., Granic A., Hollingsworth K.G., Warren C. et al. incl Sayer A.A. Mitochondrial respiratory chain function and content are preserved in the skeletal muscle of active very old men and women. Experimental Gerontology. 2018; 113 80-85 DOI: 10.1016/j.exger.2018.09.020

Donaghy P.C., Firbank M.J., Thomas A.J., Lloyd J., Petrides G. et al. Clinical and imaging correlates of amyloid deposition in dementia with Lewy bodies. Movement Disorders. 2018; 33:7 1130-1138 DOI: 10.1002/mds.27403

Dudley R., Aynsworth C., Mosimann U., Taylor J.-P., Smailes D. et al. A comparison of visual hallucinations across disorders. Psychiatry Research. 2019; 272 86-92. DOI: 10.1016/j.psychres.2018.12.052

Durcan R., Wiblin L., Lawson R.A., Khoo T.K., Yarnall A.J. et al. the ICICLE-PD Study Group. Prevalence and duration of non-motor symptoms in prodromal Parkinson's disease. European Journal of Neurology. 2019;DOI: 10.1111/ene.13919

Dutta P., Funston W., Mossop H., Ryan V., Jones R.Pearson J. et al.Randomised, double-blind, placebo-controlled pilot trial of omeprazole in idiopathic pulmonary fibrosis. Thorax. DOI:10.1136/thoraxjnl-2018-212102

Dyson J.K., Wong L.L., Bigirumurame T., Hirschfield G.M., Kendrick S. et al. on behalf of the UK-AIH Consortium. Inequity of care provision and outcome disparity in autoimmune hepatitis in the United Kingdom. Alimentary Pharmacology and Therapeutics. 2018; DOI: 10.1111/apt.14968

Dyson J.K., De Martin E., Dalekos G.N., Drenth J.P.H., Herkel J. et al. the IAIHG Consortium. Review article: unanswered clinical and research questions in autoimmune hepatitis-conclusions of the International Autoimmune Hepatitis Group Research Workshop. Alimentary Pharmacology and Therapeutics. 2018; DOI: 10.1111/apt.15111

Elder G.J., Colloby S.J., Firbank M.J., McKeith I.G., Taylor J.-P. Consecutive sessions of transcranial direct current stimulation do not remediate visual hallucinations in Lewy body dementia: A randomised controlled trial. Alzheimer's Research and Therapy. 2019; 11:1:9 DOI: 10.1186/s13195-018-0465-9

Embleton N.D., Wood C.  Metabolic outcomes in very low birthweight and preterm infants in later life [Desfechos metabólicos posteriores em recém-nascidos de muito baixo peso ao nascer e pré-termos]. Jornal de Pediatria. 2018; DOI: 10.1016/j.jped.2018.06.002

Erskine D., Ding J., Thomas A.J., Kaganovich A., Khundakar A.A. et al. incl. Attems J. Molecular changes in the absence of severe pathology in the pulvinar in dementia with Lewy bodies. Movement Disorders. 2018; DOI: 10.1002/mds.27333

Feeney C.L., Lim A.Z., Fagan E., Blain A., Bright A. et al. incl. Turnbull D.M. A case-comparison study of pregnant women with mitochondrial disease – what to expect? BJOG: An International Journal of Obstetrics and Gynaecology. 2019; DOI: 10.1111/1471-0528.15667

Firbank M.J., Parikh J., Murphy N., Killen A., Allan C.L. et al. incl. Taylor J.-P. Reduced occipital GABA in Parkinson disease with visual hallucinations. Neurology. 2018; 91:7 e675-e685 DOI: 10.1212/WNL.0000000000006007

Fisk H.L., Irvine M., Miles E.A., Lietz G., Mathers J.C. et al. Association of oily fish intake, sex, age, BMI and APOE genotype with plasma long-chain n-3 fatty acid composition. British Journal of Nutrition. 2018; 1-10. DOI: 10.1017/S000711451800106X

Foulkes A.C., Watson D.S., Carr D.F., Kenny J.G., Slidel T. Reynolds N.J. The PSORT Consortium. A Framework for Multi-Omic Prediction of Treatment Response to Biologic Therapy for Psoriasis. Journal of Investigative Dermatology. 2019; 139:1 100-107 DOI: 10.1016/j.jid.2018.04.041

French C.E., Delon I., Dolling H., Sanchis-Juan A., Shamardina O. et al. incl. Chinnery P.F. NIHR BioResource-Rare Disease, Next Generation Children Project. Whole genome sequencing reveals that genetic conditions are frequent in intensively ill children. Intensive Care Medicine. 2019; DOI: 10.1007/s00134-019-05552-x

Galperin I., Hillel I., Del Din S., Bekkers E.M.J., Nieuwboer A. et al. incl. Rochester L. Associations between daily-living physical activity and laboratory-based assessments of motor severity in patients with falls and Parkinson's disease. Parkinsonism and Related Disorders. 2019; DOI: 10.1016/j.parkreldis.2019.01.022

Goffe L., Hillier-Brown F., Hildred N., Worsnop M., Adams J. et al. incl. Penn L. Feasibility of working with a wholesale supplier to co-design and test acceptability of an intervention to promote smaller portions: An uncontrolled before-and-after study in British Fish & Chip shops. BMJ Open. 2019; 19:2  e023441 DOI: 10.1136/bmjopen-2018-023441

Grady J.P., Pickett S.J., Ng Y.S., Alston C.L., Blakely E.L. et al. incl. Mcfarland R. mtDNA heteroplasmy level and copy number indicate disease burden in m.3243A>G mitochondrial disease. EMBO Molecular Medicine. DOI: 10.15252/emmm.201708262

Gräf S., Haimel M., Bleda M., Hadinnapola C., Southgate L. et al. incl Corris P.A. Identification of rare sequence variation underlying heritable pulmonary arterial hypertension. Nature Communications. 2018; 9:1 1416 DOI: 10.1038/s41467-018-03672-4

Granic A., Mendonça N., Sayer A.A., Hill T.R., Davies K. et al. incl. Mathers J.C. Effects of dietary patterns and low protein intake on sarcopenia risk in the very old: The Newcastle 85+ study. Clinical Nutrition. 2019; DOI: 10.1016/j.clnu.2019.01.009

Gravell R., Duncan G.W., Khoo T.K., Burn D.J., Sayer A.A. et al. incl. Yarnall A.J. Multimorbidity predicts quality of life but not motor severity in early Parkinson's disease. Journal of Parkinson's Disease. 2018; 8:4 511-515 DOI: 10.3233/JPD-181428

Griffiths J., Jenkins P., Vargova M., Bowler U., Juszczak E. et al. incl. Embleton N. Enteral lactoferrin to prevent infection for very preterm infants: the ELFIN RCT. Health technology assessment (Winchester, England). 2018; 22:74 1-60 DOI: 10.3310/hta22740

Griffiths J., Jenkins P., Vargova M., Bowler U., Juszczak E. et al. incl. Embleton N.D. The ELFIN trial investigators group. Enteral lactoferrin supplementation for very preterm infants: a randomised placebo-controlled trial. The Lancet. 2019; 393: 10170 423-433 DOI: 10.1016/S0140-6736(18)32221-9

Gu S.Z., Beska B., Chan D., Neely D., Batty J.A. et al. incl. Kunadian V. Cognitive Decline in Older Patients With Non- ST Elevation Acute Coronary Syndrome. Journal of the American Heart Association. 2019; 8: 4 e011218 DOI: 10.1161/JAHA.118.011218

Hackett K.L., Deane K.H.O., Newton J.L., Deary V., Bowman S.J., Rapley T., Ng W.-F. et al. United Kingdom Primary Sjogren's Syndrome Registry. Mixed-Methods Study Identifying Key Intervention Targets to Improve Participation in Daily Living Activities in Primary Sjögren's Syndrome Patients. Arthritis Care and Research. 2018; 70:7 1064-1073 DOI: 10.1002/acr.23536

Hadar A., Milanesi E., Walczak M., Puzianowska-Kuźnicka M., Kuźnicki J. et al. incl. Attems J. SIRT1, miR-132 and miR-212 link human longevity to Alzheimer's Disease. Scientific Reports. 2018; 8:1 8465 DOI: 10.1038/s41598-018-26547-6

Hanns L., Cordingley L., Galloway J., Norton S., Carvalho L.A. et al. incl. Foster H. Depressive symptoms, pain and disability for adolescent patients with juvenile idiopathic arthritis: results from the Childhood Arthritis Prospective Study. Rheumatology (Oxford, England). 2018; 57:8 1381-1389 DOI: 10.1093/rheumatology/key088

Haste A., Penn L., Rodrigues A.M., Marques M.M., Budig K. et al. Using evidence-based guidelines to inform service provision: A structured mapping exercise within the National Health Service Diabetes Prevention Programme in England. BMC Research Notes. 2018; 11:1 510 DOI: 10.1186/s13104-018-3546-8

Hayhurst H., Anagnostou M.-E., Bogle H.J., Grady J.P., Taylor R.W. et al. incl. McFarland R. Dissecting the neuronal vulnerability underpinning Alpers’ syndrome: a clinical and neuropathological study. Brain Pathology. 2019; 29:1 97-113 DOI: 10.1111/bpa.12640

Hayhurst H., de Coo I.F.M., Piekutowska-Abramczuk D., Alston C.L., Sharma S. et al. incl. Gorman G.S.  Leigh syndrome caused by mutations in MTFMT is associated with a better prognosis. Annals of Clinical and Translational Neurology. 2019; 6:3 515-524 DOI: 10.1002/acn3.725

Henein C., Steel D.H.W. Photobiomodulation for non-exudative age-related macular degeneration. Cochrane Database of Systematic Reviews. 2018; 5: CD013029. DOI: 10.1002/14651858.CD013029

Hester K.L.M., Newton J., Rapley T., De Soyza A. Patient information, education and self-management in bronchiectasis: Facilitating improvements to optimise health outcomes. BMC Pulmonary Medicine. 2018; 18:1 80 DOI: 10.1186/s12890-018-0633-5

Hill A.T., Sullivan A.L., Chalmers J.D., De Soyza A., Elborn J.S. et al. British Thoracic Society guideline for bronchiectasis in adults. BMJ Open Respiratory Research. 2018; 5:1 e000348 DOI: 10.1136/bmjresp-2018-000348

Hill T.R., Granic A., Aspray T.J. Vitamin D and Ageing. Sub-cellular biochemistry. 2018; 90 191-220 DOI: 10.1007/978-981-13-2835-0_8

Hoo Z.H., Coates E., Maguire C., Cantrill H., Shafi N. et al. incl. Bourke S.J. Pragmatic criteria to define chronic pseudomonas aeruginosa infection among adults with cystic fibrosis. European Journal of Clinical Microbiology and Infectious Diseases. 2018; DOI: 10.1007/s10096-018-3358-8

Houghton D., Stewart C.J., Stamp C., Nelson A., Aj Ami N.J. et al. incl. Turnbull D.M.  Impact of Age-Related Mitochondrial Dysfunction and Exercise on Intestinal Microbiota Composition. Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 2018; 73:5 571-578 DOI: 10.1093/gerona/glx197

Houghton D., Hardy T., Stewart C., Errington L., Day C.P., Trenell M.I., Avery L. Systematic review assessing the effectiveness of dietary intervention on gut microbiota in adults with type 2 diabetes. Diabetologia. 2018; 1-12 DOI: 10.1007/s00125-018-4632-0

Houghton D., Zalewski P., Hallsworth K., Cassidy S., Thoma C. et al. incl. McPherson S., Anstee Q.M., Newton J.L., Trenell M.I. The degree of hepatic steatosis associates with impaired cardiac and autonomic function. Journal of Hepatology. 2019; DOI: 10.1016/j.jhep.2019.01.035

Howard R., Cort E., Bradley R., Harper E., Kelly L. et al.  incl. Barber R. ATLAS Trialists Group. Antipsychotic treatment of very late-onset schizophrenia-like psychosis (ATLAS): a randomised, controlled, double-blind trial. The Lancet Psychiatry. 2018; DOI: 10.1016/S2215-0366(18)30141-X

Howel D., Moffatt S., Haighton C., Bryant A., Becker F. et al. incl. Aspray T. Does domiciliary welfare rights advice improve health-related quality of life in independent-living, socio-economically disadvantaged people aged 60 years? Randomised controlled trial, economic and process evaluations in the North East of England. PLoS ONE. 14:1 e0209560. DOI: 10.1371/journal.pone.0209560

Hunt D., Stuart S., Nell J., Hausdorff J.M., Galna B., Rochester L., Alcock L. Do people with Parkinson's disease look at task relevant stimuli when walking? An exploration of eye movements. Behavioural Brain Research. 2018;348: 82-89. DOI: 10.1016/j.bbr.2018.03.003

Ichikawa R., Lamb C.A., Eastham-Anderson J., Scherl A., Raffals L. et al. incl. Mansfield J.C. AlphaE Integrin Expression Is Increased in the Ileum Relative to the Colon and Unaffected by Inflammation. Journal of Crohn's & colitis. 2018; 12:10 1191-1199 DOI: 10.1093/ecco-jcc/jjy084

Ito Y., Carss K.J., Duarte S.T., Hartley T., Keren B. et al. incl. Chinnery P. De Novo Truncating Mutations in WASF1 Cause Intellectual Disability with Seizures. American Journal of Human Genetics. 2018; 103:1 144-153 DOI: 10.1016/j.ajhg.2018.06.001

Jaedicke K.M., Bissett S.M., Finch T., Thornton J., Preshaw P.M. Exploring changes in oral hygiene behaviour in patients with diabetes and periodontal disease: A feasibility study. International Journal of Dental Hygiene. 2019; 17:1 55-63 DOI: 10.1111/idh.12365

Janssen X., Basterfield L., Parkinson K.N., Pearce M.S., Reilly J.K. et al. Non-linear longitudinal associations between moderate-to-vigorous physical activity and adiposity across the adiposity distribution during childhood and adolescence: Gateshead Millennium Study. International Journal of Obesity. 2018; DOI: 10.1038/s41366-018-0188-9

Jimenez-Moreno A.C., Charman S.J., Nikolenko N., Larweh M., Turner C. et al. incl. Gorman G. Analyzing walking speeds with ankle and wrist worn accelerometers in a cohort with myotonic dystrophy. Disability and Rehabilitation. 1-7 DOI: 10.1080/09638288.2018.1482376

Jones C., Markovic M., Charman S., Okwose N., Ivkovic S. et al. incl. Jakovljevic D.G. Cardiac function is not associated with glucose control in older women. Experimental Gerontology. 2019; 116 31-36. DOI: 10.1016/j.exger.2018.12.014

Jonikas M., Madill M., Mathy A., Zekoll T., Zois C.E. et al. incl. Chinnery P.F. Stem cell modeling of mitochondrial parkinsonism reveals key functions of OPA1. Annals of Neurology. 2018; DOI: 10.1002/ana.25221

Jurkute N., Majander A., Bowman R., Votruba M., Abbs S. et al. Clinical utility gene card for: inherited optic neuropathies including next-generation sequencing-based approaches. European Journal of Human Genetics. 2018; DOI: 10.1038/s41431-018-0235-y

Just S.A., Humby F., Lindegaard H., De Bellefon L.M., Durez P. et al. incl. Pratt A. Patient-reported outcomes and safety in patients undergoing synovial biopsy: Comparison of ultrasound-guided needle biopsy, ultrasound-guided portal and forceps and arthroscopic-guided synovial biopsy techniques in five centres across Europe. RMD Open. 2018; 4:2 e000799 DOI: 10.1136/rmdopen-2018-000799

Kahaly G.J., Bartalena L., Hegedüs L., Leenhardt L., Poppe K., Pearce S.H.  2018 European thyroid association guideline for the management of graves' hyperthyroidism. European Thyroid Journal. 2018; 7:4 167-186 DOI: 10.1159/000490384

Kane J.P.M., Roberts G., Petrides G.S., Lloyd J.J., O'Brien J.T., Thomas A.J. 123I-MIBG scintigraphy utility and cut-off value in a clinically representative dementia cohort. Parkinsonism and Related Disorders. 2019; DOI: 10.1016/j.parkreldis.2019.01.024

Kearsley-Fleet L., Davies R., De Cock D., Watson K.D., Lunt M. et al. incl. Isaacs J.D.  Biologic refractory disease in rheumatoid arthritis: Results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis. Annals of the Rheumatic Diseases. 2018; DOI: 10.1136/annrheumdis-2018-213378.

Keogh M.J., Wei W., Aryaman J., Wilson I., Talbot K. et al. incl. Chinnery P.F.  Oligogenic genetic variation of neurodegenerative disease genes in 980 postmortem human brains. Journal of Neurology, Neurosurgery and Psychiatry. 2018; 89:8 813-816 DOI: 10.1136/jnnp-2017-317234

Keogh M.J., Wei W., Aryaman J., Walker L., van den Ameele J. et al. incl. Chinnery P.F. High prevalence of focal and multi-focal somatic genetic variants in the human brain. Nature Communications. 2018; 9:1 4257 DOI: 10.1038/s41467-018-06331-w

Kim U.S., Jurkute N., Yu-Wai-Man P. Leber hereditary optic neuropathy—light at the end of the tunnel? Asia-Pacific Journal of Ophthalmology. 2018; 7:4 242-245 DOI: 10.22608/APO.2018293

King D.G., Walker M., Campbell M.D., Breen L., Stevenson E.J., West D.J. A small dose of whey protein co-ingested with mixed-macronutrient breakfast and lunch meals improves postprandial glycemia and suppresses appetite in men with type 2 diabetes: A randomized controlled trial. American Journal of Clinical Nutrition. 2018; 107:4 550-557 DOI: 10.1093/ajcn/nqy019

King E., O'Brien J.T., Donaghy P., Morris C., Barnett N., Olsen K., Martin-Ruiz C., Taylor J.-P., Thomas A.J. Peripheral inflammation in prodromal Alzheimer's and Lewy body dementias. Journal of Neurology, Neurosurgery and Psychiatry. 2018; 89:4 339-345 DOI: 10.1136/jnnp-2017-317134

Koene S., van Bon L., Bertini E., Jimenez-Moreno C. et al. incl.  McFarland R. Outcome measures for children with mitochondrial disease: consensus recommendations for future studies from a Delphi-based international workshop. Journal of Inherited Metabolic Disease. 2018; 10.1007/s10545-018-0229-5

Koshy A., Okwose N.C., Nunan D., Toms A., Brodie D.A. et al. incl. Jakovljevic D.G. Association between heart rate variability and haemodynamic response to exercise in chronic heart failure. Scandinavian Cardiovascular Journal. 2018; DOI: 10.1080/14017431.2019.1590629

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Unni M.N.M., Elfeky R., Rao K., Nademi Z., Chiesa R. et al. incl. Skinner R. Non-posttransplant lymphoproliferative disorder malignancy after hematopoietic stem cell transplantation in patients with primary immunodeficiency: UK experience. Journal of Allergy and Clinical Immunology. 2018; DOI: 10.1016/j.jaci.2018.02.038

Vasudev A., Thomas A.J., Grunze H. Pharmacotherapy for bipolar disorder in older people. Cochrane Database of Systematic Reviews. 2018; 2018: 11 CD010495 DOI: 10.1002/14651858.CD010495.pub2

Venter M., Tomas C., Pienaar I.S., Strassheim V., Erasmus E. et al. incl.  Ng W.-F. MtDNA population variation in Myalgic encephalomyelitis/Chronic fatigue syndrome in two populations: a study of mildly deleterious variants. Scientific Reports. 2019; 9:1 2914 DOI: 10.1038/s41598-019-39060-1

Verity C., Winstone A.M., Will R., Powell A., Baxter P. et al. incl. McFarland R. Surveillance for variant CJD: Should more children with neurodegenerative diseases have autopsies? Archives of Disease in Childhood. 2018; DOI: 10.1136/archdischild-2018-315458

Vincent A.E., White K., Davey T., Philips J., Ogden R.T. et al. incl. Turnbull D.M. Quantitative 3D Mapping of the Human Skeletal Muscle Mitochondrial Network. Cell Reports. 2019; 26:4 996 DOI: 10.1016/j.celrep.2019.01.010

Vincent A.E., Rosa H.S., Pabis K., Lawless C., Chen C. et al. incl. Turnbull D.M.  Subcellular origin of mitochondrial DNA deletions in human skeletal muscle. Annals of Neurology. 2018; DOI: 10.1002/ana.25288

Vitorio R., Stuart S., Gobbi L.T.B., Rochester L., Alcock L., Pantall A. Reduced Gait Variability and Enhanced Brain Activity in Older Adults With Auditory Cues: A Functional Near-Infrared Spectroscopy Study. Neurorehabilitation and Neural Repair. 2018; 32:11 976-987. DOI: 10.1177/1545968318805159

Warren R.B., Marsden A., Tomenson B., Mason K.J., Soliman M.M. et al. incl. Reynolds N.J. Identifying demographic, social and clinical predictors of biologic therapy effectiveness in psoriasis: a multicentre longitudinal cohort study. British Journal of Dermatology. 2018; DOI: 10.1111/bjd.16776

Wei W., Keogh M.J., Aryaman J., Golder Z., Kullar P.J. et al. incl. Attems J. & Chinnery P.F. Frequency and signature of somatic variants in 1461 human brain exomes.  Genetics in Medicine. 2018; DOI: 10.1038/s41436-018-0274-3

West S.D., Prudon B., Hughes J., Gupta R., Mohammed S.B. et al. ROSA trial investigators. Continuous positive airway pressure effect on visual acuity in patients with type 2 diabetes and obstructive sleep apnoea: a multicentre randomised controlled trial. The European respiratory journal. 2018; 52: 4 DOI: 10.1183/13993003.01177-2018

Wheatley A., Bamford C., Shaw C., Flynn E., Smith A. et al. incl. Parry S.W. Developing an Intervention for Fall-Related Injuries in Dementia (DIFRID): An integrated, mixed-methods approach 11 Medical and Health Sciences 1117 Public Health and Health Services. BMC Geriatrics. 2019; 19:1 57 DOI: 10.1186/s12877-019-1066-6

Whitworth J., Smith P.S., Martin J.-E., West H., Luchetti A. et al. incl. Talks K. Comprehensive Cancer-Predisposition Gene Testing in an Adult Multiple Primary Tumor Series Shows a Broad Range of Deleterious Variants and Atypical Tumor Phenotypes. American Journal of Human Genetics. 2018; DOI: 10.1016/j.ajhg.2018.04.013

Widdrington J.D., Gomez-Duran A., Pyle A., Ruchaud-Sparagano M.-H., Scott J. et al. incl.  Chinnery P.F. Exposure of Monocytic Cells to Lipopolysaccharide Induces Coordinated Endotoxin Tolerance, Mitochondrial Biogenesis, Mitophagy, and Antioxidant Defenses. Frontiers in immunology. 2018; 9 2217 DOI: 10.3389/fimmu.2018.02217

Wildman J.M., Moffatt S., Steer M., Laing K., Penn L., O'Brien N. Service-users' perspectives of link worker social prescribing: A qualitative follow-up study. BMC Public Health. 2019; 19:1 98 DOI: 10.1186/s12889-018-6349-x

Williams N.H., Jenkins A., Goulden N., Hoare Z. et al. incl. Isaacs J. Lessons learnt from a discontinued randomised controlled trial: Adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica (Subcutaneous Injection of Adalimumab Trial compared with Control: SCIATiC). Trials. 2018; 9:1 408 DOI: 10.1186/s13063-018-2801-6

Woitalla D., Dunac A., Safavi A., Ceravolo M.-G. incl. Pavese N., et al. A noninterventional study evaluating the effectiveness of rotigotine and levodopa combination therapy in younger versus older patients with Parkinson’s disease. Expert Opinion on Pharmacotherapy. 2018; 19:9 937-945 DOI: 10.1080/14656566.2018.1480721

Yasin S.A., Schutz P.W., Deakin C.T., Sag E., Varsani H. et al. incl. Foster H. The UK Juvenile Dermatomyositis Research Group (UK and Ireland). Histological heterogeneity in a large clinical cohort of juvenile idiopathic inflammatory myopathy: analysis by myositis autoantibody and pathological features. Neuropathology and Applied Neurobiology. 2018; DOI: 10.1111/nan.12528

Yiu Z.Z.N., Ashcroft D.M., Evans I., McElhone K., Lunt M. et al. incl. Reynolds N.J., BADBIR Study Group. Infliximab is associated with an increased risk of serious infection in patients with psoriasis in the U.K. and Republic of Ireland: results from the British Association of Dermatologists Biologic Interventions Register (BADBIR). British Journal of Dermatology. 2018; DOI: 10.1111/bjd.17036

Yiu Z.Z.N., Sorbe C., Lunt M., Rustenbach S.J., Kühl L. et al. incl. Reynolds N.J. the BADBIR Study Group. Development and validation of a multivariable risk prediction model for serious infection in patients with psoriasis receiving systemic therapy. British Journal of Dermatology. 2019; DOI: 10.1111/bjd.17421

Zhang H., Burr S.P., Chinnery P.F. The mitochondrial DNA genetic bottleneck: Inheritance and beyond. Essays in Biochemistry. 2018; 62:3 225-234 DOI: 10.1042/EBC20170096

2017/18

 

Aartsma-Rus A., Straub V., Hemmings R., Haas M., Schlosser-Weber G. et al.  Development of Exon Skipping Therapies for Duchenne Muscular Dystrophy: A Critical Review and a Perspective on the Outstanding Issues.  Nucleic Acid Therapeutics. 2017; 27:5 251-259 DOI: 10.1089/nat.2017.0682

Ahmed S.T., Alston C.L., Hopton S., He L., Hargreaves I.P. et al.  Using a quantitative quadruple immunofluorescent assay to diagnose isolated mitochondrial Complex i deficiency. Scientific Reports.  2017; 7:1 15676 DOI: 10.1038/s41598-017-14623-2

Alaimo J.T., Besse A., Alston C.L., Pang K., Appadurai V. et al. Loss-of-function mutations in ISCA2 disrupt 4Fe-4S cluster machinery and cause a fatal leukodystrophy with hyperglycinemia and mtDNA depletion.  Human Mutation. 2018; DOI: 10.1002/humu.23396

Alcock, L., Galna, B., Hausdorff, J.M., Lord, S., Rochester, L.  Gait & Posture Special Issue: Gait adaptations in response to obstacle type in fallers with Parkinson's disease.  Gait and Posture.  2018; 61 368-374 DOI: 10.1016/j.gaitpost.2018.01.030

Alcock, L., Galna, B., Perkins, R., Lord, S., Rochester, L.  Step length determines minimum toe clearance in older adults and people with Parkinson's disease.  Journal of Biomechanics. 2018; doi.org/10.1016/j.jbiomech.2017.12.002

Ali M.A., Liu Y.-F., Arif S., Tatovic D., Shariff H.  Metabolic and immune effects of immunotherapy with proinsulin peptide in human new-onset type 1 diabetes.  Science Translational Medicine. 2017; 9:402  aaf7779 DOI: 10.1126/scitranslmed.aaf7779

Alwan F., Vendramin C., Vanhoorelbeke K., Langley K., McDonald V. et al.  Presenting ADAMTS13 antibody and antigen levels predict prognosis in immune-mediated thrombotic thrombocytopenic purpura.  Blood.  2017; 130:4 466-471 DOI: 10.1182/blood-2016-12-758656

Andreasson A.S.I., Borthwick L.A., Gillespie C., Jiwa K., Scott J., Henderson P. et al.  The role of interleukin-1β as a predictive biomarker and potential therapeutic target during clinical ex vivo lung perfusion.  Journal of Heart and Lung Transplantation.  2017; 36:9 985-995 DOI: 10.1016/j.healun.2017.05.012

Arshad Q., Bonsu A., Lobo R., Fluri A.-S., Sheriff R. et al.  Biased numerical cognition impairs economic decision-making in Parkinson's disease.  Annals of Clinical and Translational Neurology.  2017; DOI: 10.1002/acn3.449

Astuti D., Sabir A., Fulton P., Zatyka M., Williams D. et al.  Monogenic diabetes syndromes: Locus-specific databases for Alström, Wolfram, and Thiamine-responsive megaloblastic anemia.  Human Mutation. 2017; 38: 764-777 DOI: 10.1002/humu.23233

Avery L., Exley C., McPherson S., Trenell M.I., Anstee Q.M., Hallsworth K.  Lifestyle Behavior Change in Patients With Nonalcoholic Fatty Liver Disease: A Qualitative Study of Clinical Practice.  Clinical Gastroenterology and Hepatology.  2017; DOI: 10.1016/j.cgh.2017.06.011

Babiloni, C., Del Percio, C., Lizio, R., Noce, G., Lopez, S. et al. Abnormalities of resting-state functional cortical connectivity in patients with dementia due to Alzheimer's and Lewy body diseases: an EEG study.  Neurobiology of Aging. 2018; 65 18-40 DOI: 10.1016/j.neurobiolaging.2017.12.023

Baczynska A.M., Shaw S.C., Patel H.P., Sayer A.A., Roberts H.C.  Learning from older peoples' reasons for participating in demanding, intensive epidemiological studies: A qualitative study.  BMC Medical Research Methodology.  2017; 17:1 167 DOI: 10.1186/s12874-017-0439-9

Baker, K.F., Isaacs, J.D.  Novel therapies for immune-mediated inflammatory diseases: What can we learn from their use in rheumatoid arthritis, spondyloarthritis, systemic lupus erythematosus, psoriasis, Crohn's disease and ulcerative colitis?  Annals of the Rheumatic Diseases. 2018; 77:2 175-187 DOI: 10.1136/annrheumdis-2017-211555

Bargiela, D., Burr, S.P., Chinnery, P.F.  Mitochondria and Hypoxia: Metabolic Crosstalk in Cell-Fate Decisions.  Trends in Endocrinology and Metabolism. 2018; doi.org/10.1016/j.tem.2018.02.002

Battersby A.C., Braggins H., Pearce M.S., Cale C.M., Burns S.O. Inflammatory and autoimmune manifestations in X-linked carriers of chronic granulomatous disease in the United Kingdom.  Journal of Allergy and Clinical Immunology. 2017; 140:2 628-630 DOI: 10.1016/j.jaci.2017.02.029

Benitez-Aguirre P.Z., Wong T.Y., Craig M.E., Davis E.A., Cotterill A. et al.  The Adolescent Cardio-Renal Intervention Trial (AdDIT): retinal vascular geometry and renal function in adolescents with type 1 diabetes. Diabetologia. 2018; 61:4 968-976. DOI: 10.1007/s00125-017-4538-2

Bezzina O.M., Gallagher P., Mitchell S., Bowman S.J., Griffiths B.  Subjective and Objective Measures of Dryness Symptoms in Primary Sjögren's Syndrome: Capturing the Discrepancy.  Arthritis Care and Research. 2017; 69:11 1714-1723 DOI: 10.1002/acr.23165

Bloom, I., Edwards, M., Jameson, K.A., Syddall, H.E., Dennison, E. et al. Influences on diet quality in older age: The importance of social factors. Age and Ageing. 2017; 46: 277-283 DOI: 10.1093/ageing/afw180

Bloom I., Lawrence W., Barker M., Baird J., Dennison E. What influences diet quality in older people? A qualitative study among community-dwelling older adults from the Hertfordshire Cohort Study, UK.  Public Health Nutrition. 2017; 20:15 2685-2693 DOI: 10.1017/S1368980017001203

Boyle M., Masson S., Anstee Q.M.  The bidirectional impacts of alcohol consumption and the metabolic syndrome: Cofactors for progressive fatty liver disease.  Journal of Hepatology.  2017; DOI: 10.1016/j.jhep.2017.11.006

Brass D., Fouweather T., Stocken D.D., Macdonald C., Wilkinson J. et al.  An observer-blinded randomized controlled pilot trial comparing localized immersion psoralen-ultraviolet A with localized narrowband ultraviolet B for the treatment of palmar hand eczema.  British Journal of Dermatology.  2018; DOI: 10.1111/bjd.16238

Brocklebank V., Johnson S., Sheerin T.P., Marks S.D., Gilbert R.D. et al.  Factor H autoantibody is associated with atypical hemolytic uremic syndrome in children in the United Kingdom and Ireland.  Kidney International. 2017; DOI: 10.1016/j.kint.2017.04.028

Bruyère O., Buckinx F., Beaudart C., Reginster J.-Y., Bauer J. et al.  How clinical practitioners assess frailty in their daily practice: an international survey.  Aging Clinical and Experimental Research.  2017; 29:5 905-912 DOI: 10.1007/s40520-017-0806-8

Burté F., Houghton D., Lowes H., Pyle A., Nesbitt S. et al.  Metabolic profiling of Parkinson's disease and mild cognitive impairment. Movement Disorders. 2017; 32:6 927-932 DOI: 10.1002/mds.26992

Cade J.E., Warthon-Medina M., Albar S., Alwan N.A., Ness A. et al. DIET@NET: Best Practice Guidelines for dietary assessment in health research. BMC Medicine. 2017; 15:1 202 DOI: 10.1186/s12916-017-0962-x

Campbell M.D., Walker M., Ajjan R.A., Birch K.M., Gonzalez J.T., West D.J.  An additional bolus of rapid-acting insulin to normalise postprandial cardiovascular risk factors following a high-carbohydrate high-fat meal in patients with type 1 diabetes: A randomised controlled trial.  Diabetes and Vascular Disease Research. 2017; 14: 336-344 DOI: 10.1177/1479164117698918

 Campbell B.C.V., van Zwam W.H., Goyal M., Menon B.K., Dippel D.W.J. et al.  Effect of general anaesthesia on functional outcome in patients with anterior circulation ischaemic stroke having endovascular thrombectomy versus standard care: a meta-analysis of individual patient data.  The Lancet Neurology.  2018; 17:1 47-53 DOI: 10.1016/S1474-4422(17)30407-6

Carapito, R., Gottenberg, J.-E., Kotova, I., Untrau, M., Michel, S. et al.  A new MHC-linked susceptibility locus for primary Sjögren's syndrome: MICA.  Human Molecular Genetics. 26: 2565-2576 DOI: 10.1093/hmg/ddx135

Carroll, B., Otten, E.G., Manni, D., Stefanatos, R., Menzies, F.M. et al.  Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis.  Nature Communications.  2018; 9:1 256 DOI: 10.1038/s41467-017-02746-z

Cassidy S., Chau J.Y., Catt M., Bauman A., Trenell M.I.  Low physical activity, high television viewing and poor sleep duration cluster in overweight and obese adults; a cross-sectional study of 398,984 participants from the UK Biobank.  International Journal of Behavioral Nutrition and Physical Activity.  2017; 14:1 57 DOI: 10.1186/s12966-017-0514-y

Chichagova V., Hallam D., Collin J., Buskin A., Saretzki G. et al.  Human iPSC disease modelling reveals functional and structural defects in retinal pigment epithelial cells harbouring the m.3243A > G mitochondrial DNA mutation.  Scientific Reports.  2017; 7:1 12320 DOI: 10.1038/s41598-017-12396-2

Clarke A., Perry E., Kelly C., De Soyza A., Heesom K. et al.  Heightened autoantibody immune response to citrullinated calreticulin in bronchiectasis: Implications for rheumatoid arthritis.  International Journal of Biochemistry and Cell Biology.  2017; 89:199-206 DOI: 10.1016/j.biocel.2017.06.013

Cobbold J.F., Atkinson S., Marchesi J.R., Smith A., Wai S.N. et al. Rifaximin in non-alcoholic steatohepatitis: An open-label pilot study.  Hepatology Research.  2017; DOI: 10.1111/hepr.12904

Connors M.H., Quinto L., McKeith I., Brodaty H., Allan L. et al.  Non-pharmacological interventions for Lewy body dementia: a systematic review.  Psychological Medicine.  2017; 1-10 DOI: 10.1017/S0033291717003257

Cooles F.A.H., Anderson A.E., Lendrem D.W., Norris J., Pratt A.G., Hilkens C.M.U., Isaacs J.D.  The interferon gene signature is increased in patients with early treatment-naive rheumatoid arthritis and predicts a poorer response to initial therapy.  Journal of Allergy and Clinical Immunology.  2017; DOI: 10.1016/j.jaci.2017.08.026

Cowell J., Buck M., Essa A.H., Clarke R., Vollmer W. et al.  Traceless Cleavage of Protein-Biotin Conjugates under Biologically Compatible Conditions.  ChemBioChem.  2017; 18:17 1688-1691 DOI: 10.1002/cbic.201700214

Craven L., Alston C.L., Taylor R.W., Turnbull D.M.  Recent Advances in Mitochondrial Disease.  Annual Review of Genomics and Human Genetics. 2017; 18: 257-275DOI: 10.1146/annurev-genom-091416-035426

Culshaw A., Ladell K., Gras S., McLaren J.E., Miners K.L. et al.  Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8 + T cell response.  Nature Immunology.  2017; 18:11 1228-1237 DOI: 10.1038/ni.3850

Cummings, B.B., Marshall, J.L., Tukiainen, T., Lek, M., Donkervoort, S. et al.  Improving genetic diagnosis in Mendelian disease with transcriptome sequencing.  Science Translational Medicine. 2017; 9: eaal5209 DOI: 10.1126/scitranslmed.aal5209

De Soyza, A., McDonnell, M.J., Goeminne, P.C., Aliberti, S., Lonni, S. et al. Bronchiectasis Rheumatoid Overlap Syndrome Is an Independent Risk Factor for Mortality in Patients With Bronchiectasis: A Multicenter Cohort Study.  Chest. 2017; 151: 1247-1254 DOI: 10.1016/j.chest.2016.12.024

Dodds, R.M., Granic, A., Davies, K., Kirkwood, T.B.L., Jagger, C., Sayer, A.A. Prevalence and incidence of sarcopenia in the very old: findings from the Newcastle 85+ Study. Journal of Cachexia, Sarcopenia and Muscle. 2017; 8: 229-237 DOI: 10.1002/jcsm.12157

Donaghy, P.C., Barnett, N., Olsen, K., Taylor, J.-P., Mckeith, I.G. et al.  Symptoms associated with Lewy body disease in mild cognitive impairment.  International Journal of Geriatric Psychiatry.  2017; DOI: 10.1002/gps.4742

Donati, B., Pietrelli, A., Pingitore, P., Dongiovanni, P., Caddeo, A. et al.  Telomerase reverse transcriptase germline mutations and hepatocellular carcinoma in patients with nonalcoholic fatty liver disease.  Cancer Medicine.  2017; 6:8 1930-1940 DOI: 10.1002/cam4.1078

Dyson J.K., Beuers U., Jones D.E.J., Lohse A.W., Hudson M.  Primary sclerosing cholangitis.  The Lancet. 2018; DOI: 10.1016/S0140-6736(18)30300-3

Echevarria C., Steer J., Heslop-Marshall K., Stenton S.C., Hickey P.M. et al.  The PEARL score predicts 90-day readmission or death after hospitalisation for acute exacerbation of COPD.  Thorax.  2017; 72:8 686-693 DOI: 10.1136/thoraxjnl-2016-209298

Elder G.J., Mactier K., Colloby S.J., Watson R., Blamire A.M. et al.  The influence of hippocampal atrophy on the cognitive phenotype of dementia with Lewy bodies. International Journal of Geriatric Psychiatry.  2017; DOI: 10.1002/gps.4719

Elder G.J., Ashcroft J., da Silva Morgan K., Umme Kulsum M., Banerjee R. et al.  Transcranial direct current stimulation in Parkinson's disease dementia: A randomised double-blind crossover trial.  Brain Stimulation. 2017; DOI: 10.1016/j.brs.2017.07.012

Evers, J.M., Laskowski, R.A., Bertolli, M., Clayton-Smith, J., Deshpande, C. et al.  Structural analysis of pathogenic mutations in the DYRK1A gene in patients with developmental disorders.  Human Molecular Genetics. 2017; 26: 519-526 DOI: 10.1093/hmg/ddw409

Farmery J.H.R., Smith M.L., Huissoon A., Furnell A., Mead A. et al.  Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data.  Scientific Reports. 2018; 8:1 1300 DOI: 10.1038/s41598-017-14403-y

Fearn A., Situmorang G.R., Fox C., Oakley F., Howarth R. et al. The NF-κ B1 is a key regulator of acute but not chronic renal injury.  Cell Death and Disease.  2017; 8:2883 DOI: 10.1038/cddis.2017.233

Feichtinger R.G., Oláhová M., Kishita Y., Garone C., Kremer L.S. et al. Biallelic C1QBP Mutations Cause Severe Neonatal-, Childhood-, or Later-Onset Cardiomyopathy Associated with Combined Respiratory-Chain Deficiencies.  American Journal of Human Genetics.  2017; 4: 525-538 DOI: 10.1016/j.ajhg.2017.08.015

Firbank M.J., O'Brien J.T., Taylor J.P.  Long reaction times are associated with delayed brain activity in lewy body dementia.  Human Brain Mapping.  2017; 39:2 633-643 DOI: 10.1002/hbm.23866

Frith J., Parry S.W. New Horizons in orthostatic hypotension.  Age and Ageing. 2017; 46: 168-174 DOI: 10.1093/ageing/afw211

Fuchs A., Gliwinski M., Grageda N., Spiering R., Abbas A.K. et al.  Minimum information about T regulatory cells: A step toward reproducibility and standardization.  Frontiers in Immunology.  2018; 8:JAN 1844 DOI: 10.3389/fimmu.2017.01844

Furtado, S., Errington, L., Godfrey, A., Rochester, L., Gerrand, C.  Objective clinical measurement of physical functioning after treatment for lower extremity sarcoma – A systematic review.  European Journal of Surgical Oncology. 2017; 43: 968-993  DOI: 10.1016/j.ejso.2016.10.002

Glasgow R.I.C., Thompson K., Barbosa I.A., He L., Alston C.L., Deshpande C. et al.  Novel GFM2 variants associated with early-onset neurological presentations of mitochondrial disease and impaired expression of OXPHOS subunits.  Neurogenetics. 2017; 1-9  DOI: 10.1007/s10048-017-0526-4

Goffe L., Penn L., Adams J., Araujo-Soares V., Summerbell C.D. et al. The challenges of interventions to promote healthier food in independent takeaways in England: Qualitative study of intervention deliverers' views.  BMC Public Health. 2018; 18:1 184 DOI: 10.1186/s12889-018-5096-3

Granic A., Davies K., Jagger C., Dodds R.M., Kirkwood T.B.L., Sayer A.A.  Initial level and rate of change in grip strength predict all-cause mortality in very old adults.  Age and Ageing. 2017; 46:6 970-976 DOI: 10.1093/ageing/afx087

Granic, A., Hil, T.R., Davies, K., Jagger, C., Adamson, A. et al. Vitamin d status, muscle strength and physical performance decline in very old adults: A prospective study. Nutrients. 2017; 9: 379 DOI: 10.3390/nu9040379

Granic A., Mendonça N., Sayer A.A., Hill T.R., Davies K. et al.  Low protein intake, muscle strength and physical performance in the very old: The Newcastle 85+ Study.  Clinical Nutrition. 2017; DOI: 10.1016/j.clnu.2017.11.005

Granic A., Mendonça N., Hill T.R., Jagger C., Stevenson E.J., Mathers J.C., Sayer A.A.  Nutrition in the very old.  Nutrients. 2018; 10:3 269 DOI: 10.3390/nu10030269

Hackett K.L., Gotts Z.M., Ellis J., Deary V., Rapley T. et al. An investigation into the prevalence of sleep disturbances in primary Sjögren's syndrome: A systematic review of the literature. Rheumatology (United Kingdom). 2017; 56: 570-580 DOI: 10.1093/rheumatology/kew443

Hackett K.L., Deary V., Deane K.H.O., Newton J.L., Ng W.-F., Rapley T.  Experience of sleep disruption in primary Sjögren’s syndrome: A focus group study.  British Journal of Occupational Therapy. 2018; 81:4 218-226. DOI: 10.1177/0308022617745006

Hadinnapola C., Bleda M., Haimel M., Screaton N., Swift A. et al.  Phenotypic Characterization of EIF2AK4 Mutation Carriers in a Large Cohort of Patients Diagnosed Clinically With Pulmonary Arterial Hypertension.  Circulation.  2017; 136:21 2022-2033 DOI: 10.1161/CIRCULATIONAHA.117.028351

Hannam K., Hartley A., Clark E.M., Sayer A.A., Tobias J.H., Gregson C.L.  Feasibility and acceptability of using jumping mechanography to detect early components of sarcopenia in community-dwelling older women.  Journal of Musculoskeletal Neuronal Interactions. 2017; 17:3 246-257 PMID: 28860427

Hanson H., Hart R.I., Thompson B., McDonagh J.E., Tattersall R., Jordan A., Foster H.E.  Experiences of employment among young people with juvenile idiopathic arthritis: a qualitative study.  Disability and Rehabilitation.  2017; DOI: 10.1080/09638288.2017.1323018

Harbron R., Ainsbury E.A., Bouffler S.D., Tanner R.J., Eakins J.S., Pearce M.S.  Enhanced radiation dose and DNA damage associated with iodinated contrast media in diagnostic X-ray imaging.  British Journal of Radiology. 2017; 90: 1079  DOI: 10.1259/bjr.20170028

Harbron R.W., Ainsbury E.A., Bouffler S.D., Tanner R.J., Pearce M.S., Eakins J.S. The impact of iodinated contrast media on intravascular and extravascular absorbed doses in X-ray imaging: A microdosimetric analysis. Physica Medica. 2018; 46 140-147. DOI: 10.1016/j.ejmp.2018.02.001

Hayes, L., Shaw, S., Pearce, M.S., Forsyth, R.J.  Requirements for and current provision of rehabilitation services for children after severe acquired brain injury in the UK: A population based study.  Archives of Disease in Childhood.  2017; 102:9 813-820 DOI: 10.1136/archdischild-2016-312166

Hernandez-Fuentes M.P., Franklin C., Rebollo-Mesa I., Mollon J., Delaney F. et al.  Long- and short-term outcomes in renal allografts with deceased donors: A large recipient and donor genome-wide association study.  American Journal of Transplantation. 2018; DOI: 10.1111/ajt.14594

Hind K., Pearce M., Birrell F.  Total and Visceral Adiposity Are Associated With Prevalent Vertebral Fracture in Women but Not Men at Age 62 Years: The Newcastle Thousand Families Study.  Journal of Bone and Mineral Research. 2017; 32: 1109-1115 DOI: 10.1002/jbmr.3085

Hirschfield G.M., Beuers U., Corpechot C., Invernizzi P. et al. EASL Clinical Practice Guidelines: The diagnosis and management of patients with primary biliary cholangitis. Journal of Hepatology. 2017; 67:1 145-172 DOI: 10.1016/j.jhep.2017.03.022

Hudson M., Sheron N., Rowe I.A., Hirschfield G.M. Should we screen for cirrhosis? BMJ (Online). 2017; 358: j3233 DOI: 10.1136/bmj.j3233

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