Paediatric and Adolescent Oncology

Researcher in laboratoryThe Paediatric Oncology Clinical Trials team, led by our research nurses Annie Parry and Lisa Price, is part of the wider Great North Children’s Hospital (GNCH) Research Unit. The Paediatric and Adolescent Oncology Unit acts as the Children’s Cancer and Leukaemia Group (CCLG) centre for running:

  • Phase III trials for a wide range of malignancies for children and young people in the region
  • Early phase clinical trials with new drugs as one of nine phase I/II centres for children and young people in the UK. We are an accredited centre of the Innovative Therapies for Children with Cancer (ITCC) consortium in Europe
  • Most national pharmacology and pharmacokinetic trials for children with cancer are conducted by our pharmacology team led by Dr Gareth Veal and Professor Alan Boddy.

Newcastle has one of the strongest translation research teams in Paediatric Oncology in Europe, based in the Newcastle Cancer Centre at the Northern Institute for Cancer Research (NICR).

The main focus of this research is to:

  • advance molecular classification of paediatric and haematological malignancies to identify novel prognostic biomarkers for therapy stratification
  • develop molecularly targeted therapies against cancer-specific alterations identified through basic research programmes
  • learn how chemotherapeutic approaches can be optimised through an improved knowledge of drug disposition and metabolism in paediatric patient populations
  • assess the relevance of drugs developed at the NICR for the therapy of paediatric cancers and haematological malignancies

This includes research on

  • Leukaemias
  • Brain tumours
  • Neuroblastoma
  • Ewing’s sarcoma

Our overall goal is to develop novel treatments for children and young people with malignancies.

Related Links

Related Staff:

Oncology

Professor Simon Bailey
Professor of Paediatric Neuro-Oncology

Professor Alan Boddy
Professor of Cancer Pharmacology

Professor Steven Clifford
Professor of Molecular Paediatric Oncology

Dr Juliet Hale

  • Telephone: +44 (0) 191 214 3027

Emeritus Professor Andy Hall
Associate Dean of Bioresources

  • Telephone: +44 (0) 191 208 7161

Professor Christine Harrison

  • Telephone: +44 (0) 191 282 1320

Professor Olaf Heidenreich
Professor of Molecular Haematology

Professor Julie Irving
Professor of Experimental Haematology

Professor John Lunec
Gillespie Prof of Molecular Oncology

Professor Anthony Moorman
Professor of Genetic Epidemiology

Dr Christopher Redfern
Reader in Retinoid Molecular Biology

Professor Roderick Skinner
Honorary Professor of Childhood Cancer

Professor Deborah Tweddle
Professor of Paediatric Oncology

Dr Gareth Veal
Senior Lecturer

Professor Josef Vormoor

  • Telephone: +44 (0) 191 282 1357

Dr Daniel Williamson
Newcastle University Research Fellow

Dr Kevin Windebank

  • Telephone: +44 (0) 191 282 1366