Efficient translational rehabilitation randomised controlled trial designs using disease progress modelling and trial simulation (2009)

Author(s): Forsyth RJ

    Abstract: Given the challenges inherent in randomised trials of rehabilitation interventions, methods are required to increase trial efficiency and information yield. This paper discusses, in a non-technical manner, a class of statistical models that is particularly suited to the task of detecting potential treatment effects against a background of spontaneous change.

      • Date: 01-12-2009
      • Journal: Neuropsychological Rehabilitation
      • Volume: 19
      • Issue: 6
      • Pages: 891-903
      • Publisher: Psychology Press
      • Publication type: Article
      • Bibliographic status: Published

      Dr Rob Forsyth
      Consultant/Senior Lecturer