Publications
The following list of papers shows the range of research carried out by users of the BioScreening Facility
We'd like to thank all those who have taken the trouble to recognise the efforts of this unit in supporting their research. If you have a paper published, please let us know so we can include it in this list.
Published in 2023
Published in 2023- Taylor R, Barnes AC, Hollingsworth KG, Irvine KM, Solovyova AS, Clark L, et al. Aetiology of Type 2 diabetes in people with a 'normal' body mass index: testing the personal fat threshold hypothesis. Clin Sci (Lond). 2023;137(16):1333-46.
- Perri G, Mathers JC, Martin-Ruiz C, Walsh JS, Eastell R, Schomburg L, et al. Selenium status in very old adults: Insights from the Newcastle 85+Study. P Nutr Soc. 2023;82(Oce3).
- Perri G, Mathers JC, Martin-Ruiz C, Parker C, Walsh JS, Eastell R, et al. Selenium status and its determinants in very old adults: insights from the Newcastle 85+ Study. Br J Nutr. 2023:1-10.
- Mlakar V, Birkenaes V, Elvsaashagen T, Ormerod M, Quintana DS, Ueland T, et al. Telomere length and verbal learning in bipolar disorders. J Affect Disord. 2023;339:555-60.
- Booth L, Redgrave R, Camacho Encina M, Tual-Chalot S, Folaranmi O, Martin-Ruiz C, et al. The senescence-associated secretory phenotype as
Publications 2022
Publications 2022- Wright JR, Deen QFE, Stevenson A, Telford-Cooke LL, Parker C, Martin-Ruiz C, et al. Plasma Myeloperoxidase as a Potential Biomarker of Patient Response to Anti-Dementia Treatment in Alzheimer's Disease. J Alzheimers Dis. 2022;89(4):1483-92.
- Tinlin-Mackenzie A, Ellis CD, Lodola A, Martin-Ruiz C, Stevens JR, Fitzsimmons C. New kid on the block: first record of juvenile American lobster, H. Milne Edwards, 1837, in European waters. Bioinvasions Rec. 2022;11(4):991-1000.
- Taylor R, Barnes AC, Irvine KM, Clark L, Al-Mrabeh A, Solovyova A, et al. Diabetes remission by weight loss in 'normal' weight people with type 2 diabetes: the ReTUNE study. Diabetologia. 2022;65(Suppl 1):S135-S.
- Hoffmann J, Tabata N, Mas-Peiro S, Spyridopoulos I, Sinning JM, Berkowitsch A, et al. Longer leukocyte telomere length is associated with myeloid inflammation and increased mortality after transcatheter aortic valve replacement. Eur Heart J Open. 2022;2(4):oeac045.
- Granic A, Martin-Ruiz C, Rimmer L, Dodds RM, Robinson LA, Spyridopoulos I, et al. Immunosenescence profiles of lymphocyte compartments and multiple long-term conditions (multimorbidity) in very old adults: The Newcastle 85+ Study. Mech Ageing Dev. 2022;208:111739.
- Granic A, Martin-Ruiz C, Rimmer L, Dodds RM, Robinson L, Spyridopoulos I, et al. Immunosenescence Profiles and Multiple Long-Term Conditions in Very Old Adults: The Newcastle 85+Study. Age and Ageing. 2022;51(Suppl 2).
- Donaghy PC, Cockell SJ, Martin-Ruiz C, Coxhead J, Kane J, Erskine D, et al. Blood mRNA Expression in Alzheimer's Disease and Dementia With Lewy Bodies. Am J Geriatr Psychiatry. 2022;30(9):964-75.
- Amin HA, Cordell HJ, Martin-Ruiz C, Robinson L, Kirkwood T, Blakemore AI, et al. No Evidence That Genetic Variation at the Klotho Locus Is Associated With Longevity in Caucasians from the Newcastle 85+ Study and the UK Biobank. J Gerontol A Biol Sci Med Sci. 2022;77(3):457-61.
Published in 2021
Published in 2021
- Oliver M. Shannon, Ammar W. Ashor, Filippo Scialo, Gabriele Saretzki, Carmen Martin-Ruiz, Jose Lara, Jamie Matu,Alex Griffiths,Natassia Robinson,Lionetti Lillà, Emma Stevenson, Blossom C. M. Stephan, Anne Marie Minihane, Mario Siervo, John C. Mathers Mediterranean diet and the hallmarks of ageing, Eur J Clin Nut., Jan 2021.
- Leah Palapar, Ngaire Kerse, Anna Rolleston, Wendy P J den Elzen, Jacobijn Gussekloo , Jeanet W Blom, Louise Robinson, Carmen Martin-Rui , Rachel Duncan, Yasumichi Arai , Midori Takayama, Ruth Teh, TULIP Consortium. Anaemia and physical and mental health in the very old: An individual participant data meta-analysis of four longitudinal studies of ageing Age Ageing. Jan 2021
Published in 2020
Published in 2020- D. Chan, C. Martin-Ruiz, G. Saretzki, D. Neely, W. Qiu, and V. Kunadian. The association of telomere length and telomerase activity with adverse outcomes in older patients with non-ST-elevation acute coronary syndrome (in eng) PLoS One Jan 2020
- Alan J Thomas ,Calum A Hamilton , Paul C Donaghy , Carmen Martin-Ruiz , Chris M Morris , Nicola Barnett , Kirsty Olsen , John-Paul Taylor , John T O'Brien Prospective Longitudinal Evaluation of Cytokines in mild cognitive impairment due to AD and Lewy Body Disease (in eng) Int J Geriatr Psychiatry. Jun 19 2020.
- Martin-Ruiz, Carmena, Williams-Gray, Caroline H. Yarnall, Alison J Boucher, John J. Lawson, Rachael A. Wijeyekoon, Ruwani S. Barker, Roger A. Kolenda, Claire Parker, Craig, Burn, David, Von Zglinicki, Thomase, Saretzki Gabriel, Senescence and Inflammatory Markers for Predicting Clinical Progression in Parkinson's Disease: The ICICLE-PD Study (in eng) J Parkinsons Dis, Jan 2020
- Carmen Martin-Ruiz, Jedrzej Hoffmann , Evgeniya Shmeleva , Thomas von Zglinicki , Gavin Richardson , Lilia Draganova , Rachael Redgrave , Joanna Collerton , Helen Arthur , Bernard Keavney , Ioakim Spyridopoulos CMV-independent increase in CD27-CD28+ CD8+ EMRA T cells is inversely related to mortality in octogenarians (in eng), NPJ Aging Mech Dis Jan 2020
- Antoneta Granic , Carmen Martin-Ruiz , Richard M Dodds , Louise Robinson , Ioakim Spyridopoulos , Thomas Bl Kirkwood , Thomas von Zglinicki , Avan A Sayer Immunosenescence profiles are not associated with muscle strength, physical performance and sarcopenia risk in very old adults: The Newcastle 85+ Study Mech Ageing Dev, Sept 2020
Published in 2019
Published in 2019- Nuno Mendonça, Carol Jagge , Antoneta Granic, Carmen Martin-Ruiz , John C Mathers, Chris J Sea , Tom R Hill Plasma Vitamin B12, Supplementation and Mortality, J Gerontol A Biol Sci Med Sci. Jan 2019
- Eleanor King, John Tiernan O'Brien , Paul Donaghy , Christopher Morris , Nicola Barnett , Kirsty Olsen, Carmen Martin-Ruiz, John Paul Taylor, Alan J Thomas Peripheral inflammation in mild cognitive impairment with possible and probable Lewy body disease and Alzheimer's disease (in eng), Int Psychogeriatr April 2019
- Eleanor King , John O'Brien , Paul Donaghy , Caroline H Williams-Gray , Rachael A Lawson , Christopher M Morris, Nicola Barnett, Kirsty Olsen, Carmen Martin-Ruiz, David Burn, Alison J Yarnall, John-Paul Taylor, Gordan Duncan, Tien K Khoo, Alan Thomas Inflammation in mild cognitive impairment due to Parkinson's disease, Lewy body disease, and Alzheimer's disease (in eng), Int J Geriatr Psychiatry. April 2019
- J. Deelen et al., A meta-analysis of genome-wide association studies identifies multiple longevity genes, (in eng), Nat Commun, Aug 2019.
- S. Boag, E. Andreano, C. Martin-Ruiz, and I. Spyridopoulos, Role of Immunosenescence in Coronary Artery Disease, in Handbook of Immunosenescence: Basic Understanding and Clinical Implications. May 2019
- Melissa Bateson, Abraham Aviv, Laila Bendix , Athanase Benetos , Yoav Ben-Shlomo , Stig E Bojesen , Cyrus Cooper , Rachel Cooper , Ian J Deary , Sara Hägg , Sarah E Harris , Jeremy D Kark , Florian Kronenberg , Diana Kuh , Carlos Labat , Carmen M Martin-Ruiz , Craig Meyer , Børge G Nordestgaard , Brenda W J H Penninx , Gillian V Pepper , Dóra Révész , M Abdullah Said , John M Starr , Holly Syddall , William Murray Thomson , Pim van der Harst , Mary Whooley , Thomas von Zglinicki , Peter Willeit , Yiqiang Zhan , Daniel Nettle Smoking does not accelerate leucocyte telomere attrition: a meta-analysis of 18 longitudinal cohorts (in eng), R Soc Open Sci, Jun 2019.
- M. Aas et al., Telomere Length is associated with childhood trauma in patients with severe mental disorders. Schizophrenia Bulletin, March 2019.
Published in 2018
Published in 2018- N. Mendonca et al., Elevated Total Homocysteine in All Participants and Plasma Vitamin B12 Concentrations in Women Are Associated With All-Cause and Cardiovascular Mortality in the Very Old: The Newcastle 85+ Study, J Gerontol A Biol Sci Med Sci. Aug 2018
- R. E. Marioni et al., The epigenetic clock and telomere length are independently associated with chronological age and mortality, Int J Epidemiol. Feb 1 2018.
- E. King et al., Peripheral inflammation in prodromal Alzheimer's and Lewy body dementias, J Neurol Neurosurg Psychiatry, Apr 2018.
Published in 2017
Published in 2017- D. Nettle et al., Early-life adversity accelerates cellular ageing and affects adult inflammation: Experimental evidence from the European starling, Sci Rep. Jan 17 2017.
- N. Mendonca et al., One-Carbon Metabolism Biomarkers and Cognitive Decline in the Very Old: The Newcastle 85+ Study, J Am Med Dir Assoc. Sep 2017
- N. Mendonca et al., Homocysteine, Tryptophan, and Cognition in the Very Old, J Am Med Dir Assoc, Oct 2017.
- K. E. McAleese et al., Parietal white matter lesions in Alzheimer's disease are associated with cortical neurodegenerative pathology, but not with small vessel disease, Acta Neuropathol, Sep 2017.
- S. E. Harris et al., Age-related gene expression changes, and transcriptome wide association study of physical and cognitive aging traits, in the Lothian Birth Cohort 1936, Aging (Albany NY), Dec 1 2017.
- A. Granic et al., Grip strength and inflammatory biomarker profiles in very old adults, Age Ageing, Nov 1 2017.
Published in 2016
Published in 2016- I. Spyridopoulos et al., CMV seropositivity and T-cell senescence predict increased cardiovascular mortality in octogenarians: results from the Newcastle 85+ study, Aging Cell, April 2016
- S. H. Pearce et al., Serum Thyroid Function, Mortality and Disability in Advanced Old Age: The Newcastle 85+ Study, J Clin Endocrinol Metab, Nov 2016.
- D. Nettle et al., Brood size moderates associations between relative size, telomere length, and immune development in European starling nestlings Ecol Evol, Nov 2016.
- N. Mendonca et al., Intakes of Folate and Vitamin B12 and Biomarkers of Status in the Very Old: The Newcastle 85+ Study, Nutrients, Sep 28 2016.
- R. E. Marioni et al., The epigenetic clock and telomere length are independently associated with chronological age and mortality, Int J Epidemiol, Apr 13 2016.
- T. R. Hill et al., Serum 25-hydroxyvitamin D concentration and its determinants in the very old: the Newcastle 85+ Study, Osteoporos Int, March 2016.
- S. E. Harris et al., Longitudinal telomere length shortening and cognitive and physical decline in later life: The Lothian Birth Cohorts 1936 and 1921 Mech Ageing Dev. March 2016
- Ikeh MA et al., Pho4 mediates phosphate acquisition in Candida albicans and is vital for stress resistance and metal homeostasis. Molecular Biology of the Cell 2016,
Published in 2015
Published in 2015- L. Walker et al., Neuropathologically mixed Alzheimer's and Lewy body disease: burden of pathological protein aggregates differs between clinical phenotypes Acta Neuropathol, May 2015.
- A. Mitnitski et al., Age-related frailty and its association with biological markers of ageing BMC Med, Jul 13 2015.
- N. G. Masca et al., RIPOSTE: a framework for improving the design and analysis of laboratory-based research, Elife May 7 2015.
- C. M. Martin-Ruiz et al., Reproducibility of telomere length assessment: an international collaborative study, Int J Epidemiol, Oct 2015.
- C. M. Martin-Ruiz et al., Reproducibility of Telomere Length Assessment--An International Collaborative Study, Int J Epidemiol, Oct 2015.
- C. M. Martin-Ruiz et al., Reproducibility of telomere length assessment: Authors' Response to Damjan Krstajic and Ljubomir Buturovic Int J Epidemiol, Oct 2015.
- A. Granic et al., Serum 25-hydroxyvitamin D and cognitive decline in the very old: the Newcastle 85+ Study, Eur J Neurol, Jan 2015.
- A. Granic et al., 25-hydroxyvitamin D and increased all-cause mortality in very old women: the Newcastle 85+ study, J Intern Med, Apr 2015.
- Y. Arai et al., Inflammation, But Not Telomere Length, Predicts Successful Ageing at Extreme Old Age: A Longitudinal Study of Semi-supercentenarians, EBioMedicine, July 2015
- Dubarry M, Lawless C, Banks AP, Cockell S, Lydall D. Genetic Networks Required to Coordinate Chromosome Replication by DNA Polymerases α, δ, and ε in Saccharomyces cerevisiae. G3: Genes, Genomes, Genetics August 2015.
- Narayanan S, Dubarry M, Lawless C, Banks AP, Wilkinson DJ, Whitehall SK, Lydall D. Quantitative Fitness Analysis Identifies exo1∆ and Other Suppressors or Enhancers of Telomere Defects in Schizosaccharomyces pombe. PloS ONE July 2015
Published in 2014
Published in 2014- L. Wiley et al., Reactive oxygen species production and mitochondrial dysfunction in white blood cells are not valid biomarkers of ageing in the very old, PLoS One, March 2014
- S. Masi et al., Rate of telomere shortening and cardiovascular damage: a longitudinal study in the 1946 British Birth Cohort, Eur Heart J, Dec 7 2014.
- C. Martin-Ruiz and T. von Zglinicki, Biomarkers of healthy ageing: expectations and validation, Proc Nutr Soc. Aug 2014.
- M. Gardner et al., Gender and telomere length: systematic review and meta-analysis, Exp Gerontol, Mar 2014.
- J. Deelen et al., Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age, Hum Mol Genet, August 2014.
- J. Collerton et al., Utility of NT-proBNP as a rule-out test for left ventricular dysfunction in very old people with limiting dyspnoea: the Newcastle 85+ Study, BMC Cardiovasc Disord, Sept 2014.
- J. Collerton et al., Acquisition of aberrant DNA methylation is associated with frailty in the very old: findings from the Newcastle 85+ Study, Biogerontology, August 2014.
- D. Baylis et al., Inflammation, telomere length, and grip strength: a 10-year longitudinal study, Calcif Tissue Int, Jul 2014.
Acknowledging the Facility
If you've used our Facility, please recognise and acknowledge it in your publications and grant applications. Although you pay to use the Facility, the full cost of any scientific core facility is not passed on to the end user.
The Faculty of Medical Sciences look at the quantity and quality of publications from the University research themes containing data with direct links to the BioScreening usage. This is used as a metric of facility performance (alongside the number of usage hours and cost recovery).
Acknowledging the BioScreening Facility in your papers, posters and talks will help to ensure we continue to receive faculty subsidy and continue to offer excellent access rates.
Using data generated within the BioScreening Facility
Using data generated within the BioScreening FacilityIn a publication that includes data (main figures or supplemental) generated within the BioScreening Facility, please state:
“We acknowledge the Newcastle University BioScreening Facility for assistance with the generation of data”.
Working closely with BioScreening staff members
Working closely with BioScreening staff membersIf a member of the BioScreening team has worked closely with you on a project, you should acknowledge this.
It is good practice to include their name in the acknowledgement section at least.
In situations where they have made substantial intellectual input, you can offer them a co-authorship. This should be discussed at the earliest opportunity.