Institute of Cellular Medicine

Staff Profile

Dr Christopher Johnson

Research Associate

Background


Research Interests

My current role within the i-sense EPSRC IRC in Early Warning Sensing Systems for Infectious Diseases involves the use of isothermal amplification platforms for the rapid detection of infectious organisms such as C. difficile and MRSA as well as the development of capture reagents against novel bacterial biomarkers. Earlier Postdoctoral positions involved investigating the translocation of toxins produced by E. coli, through the Gram negative outer membrane with a view to use these molecules as novel antibiotics. A biophysics based approach was used to study the mechanism of toxin translocation through the bacterial membrane, spanning techniques including small angle neutron scattering/X-ray scattering, circular dichroism, surface plasmon resonance and isothermal titration calorimetry. 


Current and Recent Funding 

Researcher Co-investigator:   i-sense2, IRC in Agile Early Warning Sensing Systems for Infectious Diseases and Antimicrobial Resistance: EPSRC IRC (£3.9M, October 2018 -September 2022).

Postdoctoral Researcher:   Ultra-Sensitive Enhanced NanoSensing of Anti-Microbial Resistance (u-Sense): EPSRC IRC Next Steps Plus award (£1.39M October 2018 - August 2022).

Postdoctoral Researcher: Early-Warning Sensing Systems for Infectious Diseases: EPSRC IRC (£11.1M, Oct 2013 - Sept 2019) 

Publications