Institute of Cellular Medicine

Staff Profile

Dr James Lordan

Consultant Physician and Honorary Clinical Senior Lecturer in Respiratory Medicine


I am a member of the Respiratory Medicine Research Group

I carried out a PhD in asthma Prof Stephen Holgate’s unit in Southampton, and have maintained a research interest ever since. Details are found in the adjacent RESEARCH section, and selected manuscripts are shown the PUBLICATIONS section.

I am a clinician with a special interest in (and with specific clinics devoted to) difficult asthma, pulmonary vasculitis, pulmonary hypertension, lung transplantation, and pulmonary fibrosis.


Current Clinical & Research interests

Difficult Asthma, Therapeutics & Epithelial mechanisms in Lung Transplantation, Pulmonary Hypertension, Pulmonary Vasculitis and Interstitial lung disease

Current Clinical Trials as Principal investigator

1. A Study To Measure Serum Periostin, Asthma-Related Biomarkers And Response To Prednisolone In Adult And Adolescent Patients With Severe Oral Corticosteroid?Dependent Asthma

2. Plasma exchange and glucocorticoid dosing in the treatment of antineutrophil cytoplasm antibody associated vasculitis: an international randomized controlled trial.

3. Ongoing co-investigator in Pulmonary hypertension, lung transplantation, asthma and previous investigator in Interstitial lung disease clinical trials.

Collaborators, Current & Previous

Bart Vanaudenaerde, University of Leuven, Belgium (Role of pollution and lung Transplantation outcomes international study)

Prof Liam Heaney, Belfast City Hospital, Northern Ireland

Prof David Jayne, Addenbrooks Hospital, Cambridge, UK

Dr Chris Ward, Dr Malcolm Brodlie, Prof John Simpson, Prof Geoff Pearson, Dr Cath Hilkiens, Dr Ian Forrest,

Dr Alison Brown, Dr Laura Baines, Mr Dayalan Karat, Dr Anthony deSoyza, Prof Paul Corris, Prof AndyFisher,
University of Newcastle.


I regularly teach students as part of the Newcastle MBBS programme

Current PhD student

Dr. Melissa McDonnell - The Role of Extra-oesophageal Reflux in the Pathogenesis and Progression of Bronchiectasis