Institute of Cellular Medicine

Staff Profile

Dr Philip Hampton

Associate Clinical Lecturer

Background

Dr Hampton is an NHS Consultant Dermatologist at the Royal Victoria Infirmary and an associate lecturer at Newcastle University. He is active in a number of research projects in close collaboration with university colleagues. Recent projects included 1. An observational study that demonstrated the association between alcohol consumption and having worse eczema and psoriasis 2. A clinical trial showed for the first time that a form of light therapy,  Narrow Band UVB was an effective treatment for palmar hand eczema and  3.  Work continues on the evaluation of a mobile phone app for skin self monitoring;  www.myskinselfie.com . We are investigating how self-monitoring can benefit patients in the management of their skin problems and also whether the app can be used to provide better access to specialist care, in the first instance, in patients with acne. This project is in collaboration with Prof Patrick Olivier in the School of Computing.

Journal Publications

P. Hampton, S. Meggitt: Better definition of hidradenitis suppurativa subtypes is needed to progress disease-specific treatment outcomes. British Journal of Dermatology 04/2017; 176(4):862-863., DOI:10.1111/bjd.15431

K Al-Jefri, D Newbury-Birch, C.R. Muirhead, E Gilvarry, V Arajo-Soares, N.J. Reynolds, E Kaner, P.J. Hampton: High prevalence of alcohol use disorders in patients with inflammatory skin diseases. British Journal of Dermatology 03/2017;, DOI:10.1111/bjd.15497

S M Brown, KA Aljefri, R Waas, P J Hampton: Systemic medications used in treatment of common dermatological conditions: Safety profile with respect to pregnancy, breast feeding and content in seminal fluid. Journal of Dermatological Treatment 01/2017;, DOI:10.1080/09546634.2016.1202402

C. Schaefer, C. Mamolo, J.C. Cappelleri, S. Daniel, C. Le, S. Tatulych, C.E.M. Griffiths, P.J. Hampton: Treatment Patterns and Outcomes among Adults Admitted to Hospital in the United Kingdom (UK) due to Plaque or Erythrodermic Psoriasis. British Journal of Dermatology 12/2016;, DOI:10.1111/bjd.15270

L. Nemazee, P. J. Hampton: Despite numerous recent advances in dermatological therapy, the need for inpatient dermatology care remains considerable. Clinical and Experimental Dermatology 12/2016;, DOI:10.1111/ced.12926

I L Smith, S Brown, J Nixon, F C Cowdell, S Ersser, C Fernandez, M Goodfield, C M Green, P Hampton, J T Lear, C H Smith, L Sunderland, S Tubeuf, M Wittmann: Treatment of severe, chronic hand eczema: Results from a UK-wide survey. Clinical and Experimental Dermatology 07/2016; 42(2)., DOI:10.1111/ced.13015

Sarah Madeline Brown, Philip Jeremy Hampton: Haemolytic Anaemia Following High Dose Intravenous Immunoglobulin Treatment for Epidermolysis Bullosa Acquisita. Pharmacology & Pharmacy 01/2016; 07(01):25-28., DOI:10.4236/pp.2016.71004

Firas Constantin Kreeshan, Philip Jeremy Hampton: Delayed hypersensitivity reaction to intralesional triamcinolone acetonide following treatment for alopecia areata. Intradermal testing. Journal of Dermatological Case Reports 12/2015; 9(4)., DOI:10.3315/jdcr.2015.1216

J.R. Chalmers, F. Wojnarowska, G. Kirtschig, A.J. Nunn, D.J. Bratton, J. Mason, K.A. Foster, D. Whitham, H.C. Williams, Rainer Hügel, Calum Lyon, Williams H., Mason J., Mcdermott M., Yong A., Chriba M., Banks-Dunnell K., Butcher D., Cox N., Nik M., Gilbanks K., Davies K., Lawton N., Alkali A., Wells L., English J., Malik M., Wooton C., Murphy R., Batchlor J., Simpson R., Burden-Teh E., Yaakub A., Lam M., Wong G., Davies-Jones S., Llewellyn J., Venning V., Mcpherson T., Cooper S., Matter L., Westmoreland M., Chapman A., Estfan Y., Miller N., Harrison M., Reeves G., Kaushal G., Seukeran D., Malhomme H., Dua J., Higgins C., Ong S., Allen C., Clayton R., Taylor P., Wilmott K., Foxton J., King J., Grimwood G., Bower C., Charman C., Varghese J., James R., Hill T., Hayward M., Bottomley W., Bell H., Azurdia R., Walsh M., Ngan K., Jayasekera P., Angit C., Turner A., Marsh D., Young A., Lovell C., Wright A., Velangi S., Szczecinska W., Talsamia N., Jutley G., Ogboli M., Halpern J., Shumba T., Gawkrodger D., Cousen P., Aldoori N., Ott J., Morgan C., Diaz A., Ravenscroft J., Panchal M., Bayliss E., Trinh H., Heeley C., Novak A., Adams J., Frost T., Liu A., Burns S., Clepa A., Benham D., Carmichael A., Kapadia A., Reddy H., Fatah S., Dalrimple J., Charles-Holmes R., Carter J., Degiovanni C., Bedlow A., Jones C., Seaton W., Hotchkiss K., Akhras V., Wee J., Winhoven S., Rutter K., Buckley D., Whittam L., Wojnarowska F., Gossain S., Hempel H., Gingell J., Toft S., Arnold J., Lewis V., Wachsmuth R., Hampton P., Taghipour K., Kapur N., Wakeel R., George S., Friedman A., Reeves L., Akworth B., Hussain K., Horton K., Warner K., Martin-Clavijo A., Grimes E., Ilchyshyn A., Dharma B., Imran F., Dunnill G., Bray A., Harmen K., Alexandrov A., Narayana K., Johnston G., Helbling I., Shelley C., Hill A., Kirkup M., Santander H., Simmons D., Lloyd-Jones H., Saunders G., Gibbon K., Bewley A., Wachsmuthl R., Edwards F., Boyle J., Davey M., Lyon C., Flowerdow M., Green J., Ormerod A., Craig F., Hussain F., Lawson L., Anstey A., Mitchell S., Watkins C., Vestey J., Halliday S., Sterling J., Martin P., Ross S., Shipley D., Veysey E., Johnson A., Blackford S., Sidhu S., Thomas C., Patel G., Ingram J., Batchelor J., Motley R., Morris A., Long C., Abbott R., Chowdhury M., Scourfield S., Thomas A., Reilly G., Waters A., Dawe R., Chattopadhyay M., Rakvit P., Yule S., Leman J., Torley D., May C., Günther C., Wozel G., Blümlein J., Sticherling M., Renner R., Wallace M., Alt P., Friedel S., Schmidt E., Meyersburg D., Beek N., Knuth-Rehr D., Steinbrink K., Hagedorn G., Luger T., Tsianakas A., Ben-Zvi G., Ortiz Am, Broecker E., Benoit S., Hosp C., Stoevesandt J., Anders D., Poppe H., König S., Gläser R., Hügel R., Nunn A., Haque-Hussain S., Nasr I., Ranasinghe A., Wahie S., Freeman K., Nataranjan S., Rajan N., Ellis R., Thomson A., Sripathy T., Bajaj V., Bratton D., Vatve M., Ferguson A., Riches K., Verpetinske I., Cheung S., Taylor M., Duarte-Williamson E., Cowley C., Kulakov E., Mann J., Chalmers J., Potter A., Antony F., Williams J., Moore L., Herske J., Atkinson S., Groves R., Benton E., Sreeneebus H., Jones S., Onions C., Layton A., Pearson J., Whitton A., Walker B., Strauss R., Das S., Marshall E., Goddard N., Savage L., Kwok J., Foster K., Walker M., Broome M., Law G., Hussey J., Wray A., Walton S., Zaman R., Kapdia A., Smith V., Jones P., Kirtschig G., Ashton K., Aziz O., Gibbs S., Rallan D., Hood S., Salvary I., Graham R., Gajawada V., Simmons S., Woods J., Whitham D., Azam A., Amor K., Harry M., Smith N., Hendy S., Sirdefield D., Levell N., Cassie-Chetty N., Coelho R., Millington G.: A randomised controlled trial to compare the safety and effectiveness of doxycycline (200 mg/day) with oral prednisolone (0.5 mg/kg/day) for initial treatment of bullous pemphigoid: A protocol for the Bullous Pemphigoid Steroids and Tetracyclines (BLISTER) Trial. British Journal of Dermatology 02/2015; 173(1)., DOI:10.1111/bjd.13729

S Darné, L.C. Stewart, P.M. Farr, P.J. Hampton: Investigation of cutaneous photoadaptation to narrowband ultraviolet B. British Journal of Dermatology 10/2013; 170(2)., DOI:10.1111/bjd.12662

Tee Wei Siah, Philip J Hampton: The effectiveness of tap water iontophoresis for palmoplantar hyperhidrosis using a Monday, Wednesday, and Friday treatment regime. Dermatology online journal 04/2013; 19(3):14.

Konrad Staines, Philip J Hampton: Treatment of mucous membrane pemphigoid with the combination of mycophenolate mofetil, dapsone, and prednisolone: A case series. 07/2012; 114(1):e49-56., DOI:10.1016/j.oooo.2012.01.030

Philip J Hampton, Ralph Jans, Ross J Flockhart, Graeme Parker, Nick J Reynolds: Lithium Regulates Keratinocyte Proliferation Via Glycogen Synthase Kinase 3 and NFAT2 (Nuclear Factor of Activated T Cells 2). Journal of Cellular Physiology 04/2012; 227(4):1529-37., DOI:10.1002/jcp.22872

A E Chambers, P J Hampton, K S Staines: A Case Of Strawberry Gingivitis. Clinical and Experimental Dermatology 03/2012; 38(2)., DOI:10.1111/j.1365-2230.2012.04346.x

Natasha Walmsley, Philip Jeremy Hampton: Bullous pemphigoid triggered by swine flu vaccination: Case report and review of vaccine triggered pemphigoid. Journal of Dermatological Case Reports 12/2011; 5(4):74-6., DOI:10.3315/jdcr.2011.1081

P J Hampton, K Wood, C M Lawrence: Painless unilateral ulceration of the lower leg. Clinical and Experimental Dermatology 07/2009; 34(4):545-6., DOI:10.1111/j.1365-2230.2008.02726.x

P.J. Hampton, O.K. Ross, N.J. Reynolds: Increased nuclear ?-catenin in suprabasal involved psoriatic epidermis. British Journal of Dermatology 01/2008; 157(6):1168-77., DOI:10.1111/j.1365-2133.2007.08195.x

Philip Jeremy. Hampton: The role of glycogen synthase kinase-3ß in the pathogenesis of lithium provoked psoriasis /.

P J Hampton, B Angus, AJ Carmichael: A case of Schopf-Schulz-Passarge syndrome. Clinical and Experimental Dermatology 10/2005; 30(5):528-30., DOI:10.1111/j.1365-2230.2005.01855.x

P J Hampton, N J Reynolds: Calcineurin inhibitors for the treatment of skin disease: How do they work?. Clinical & Experimental Allergy 06/2005; 35(5):549-50., DOI:10.1111/j.1365-2222.2005.02255.x

P J Hampton, P M Farr, B L Diffey, J J Lloyd: Implication for photosensitive patients of ultraviolet A exposure in vehicles. British Journal of Dermatology 11/2004; 151(4):873-6., DOI:10.1111/j.1365-2133.2004.06098.x

P J Hampton, N Leonard, C M Lawrence: Case 5. Giant-cell tumor of tendon sheath. Clinical and Experimental Dermatology 10/2003; 28(5):573-4.

P. J. Hampton, N. Leonard, C. M. Lawrence: Case 5. Clinical and Experimental Dermatology 08/2003; 28(5):573 - 574., DOI:10.1046/j.1365-2230.2003.01339.x

AK Lampe, P J Hampton, K Woodford-Richens, I Tomlinson, C M Lawrence, F S Douglas: Laugier-Hunziker syndrome: An important differential diagnosis for Peutz-Jeghers syndrome. Journal of Medical Genetics 07/2003; 40(6):e77., DOI:10.1136/jmg.40.6.e77

P. Hampton: Anodipsia nervosa a variant of anorexia in patients with end-stage renal disease. Nephrology Dialysis Transplantation 05/2002; 17(5):942-943., DOI:10.1093/ndt/17.5.942

P Hampton, L Harrison, D Gray: Demand for hospital services following admission with suspected myocardial infarction in 1983 and 1989. Health trends 02/1993; 25(3):91-4.

Conference Proceedings

P. Hampton, K. Al-Jefri, C. Muirhead, D. Newbury-Birch, K. Kaner, E. Gilvarry, V. Araujo-Soares, N. Reynolds: Examining the prevalence of alcohol use disorders in patients with skin disease. 20th Anniversary Conference of the British-Skin-Foundation on Skin Deep; 10/2016

K. Aljefri, C. Muirhead, D. Newbury-Birch, E. Kaner, E. Gilvarry, V. Araujo-Soares, N. J. Reynolds, P. Hampton: Examining the prevalence of Alcohol Use Disorders (AUD) in patients with skin disease, a cross-sectional study. 45th Annual Meeting of the European-Society-for-Dermatological-Research; 09/2015

D. Brass, P. Farr, N. Reynolds, D. Stocken, C. Macdonald, S. Wahie, S. Weatherhead, J. Wilkinson, J. Lloyd, S. Hill, T. Fouweather, P. Hampton: An observer-blinded randomized controlled pilot study comparing localised psoralen-ultraviolet A with localized narrowband ultraviolet B for the treatment of hand eczema. 95th Annual Meeting of the British-Association-of-Dermatologists; 07/2015

K. Aljefri, P. J. Hampton, N. J. Reynolds: Predictors of response to increasing the dose of etanercept: results of an audit. 93rd Annual Meeting of the British-Association-of-Dermatologists; 07/2013

H. Al-Rawi, K. S. Staines, P. J. Hampton: Mucous membrane pemphigoid successfully treated with the combination of mycophenolate mofetil and dapsone. 90th Annual Meeting of the British-Association-of-Deermatologists; 07/2010

P. J. Hampton, O. K. Ross, N. J. Reynolds: Lithium inhibits the transcriptional activation, mRNA and protein expression of transglutaminase 1 in keratinocytes. Annual Meeting of the British-Society-for-Investigative-Dermatology; 05/2007

P. J. Hampton, G. Parker, N. J. Reynolds: Role of glycogen synthase kinase 3 beta in regulating keratinocyte proliferation and lithium-provoked psoriasis. 36th Annual Meeting of the European-Society-of-Dermatology-Research; 08/2006

PJ Hampton, NJ Reynolds: Lithium and glycogen synthase kinase 3 beta regulate proliferation of human keratinocytes. Annual Meeting of the British-Society-for-Investigative-Dermatology; 07/2006

P. J. Hampton, N. J. Reynolds: Fumaric acid esters for psoriasis: a report of therapeutic experience and side effect profile in 17 patients. 86th Annual Meeting of the British-Association-of-Dermatologists; 07/2006

PJ Hampton, NJ Reynolds: Lithium inhibits the activation of the keratinocyte transglutaminase promoter through a GSK-3 beta-independent pathway. Meeting of the Royal-College-of-Physicians; 01/2006

PJ Hampton, NJ Reynolds: beta-Catenin regulates keratinocyte transglutaminase transcriptional activation, and increased nuclear beta-catenin is found in involved psoriatic epidermis. 85th Annual Meeting of the British-Association-of-Dermatologists; 07/2005

PJ Hampton, NJ Reynolds: The role of beta-catenin in normal human keratinocytes and involved and uninvolved psoriatic skin. 34th Annual Meeting of the European-Society-for-Dermatological-Research; 08/2004

PJ Hampton, S Needham, NJ Reynolds: Eosinophihc panniculitis - an unusual cutaneous complication of insulin therapy. 83rd Annual Meeting of the British Association of Dermatologists; 07/2003

Publications