Institute of Cellular Medicine

Staff Profile

Dr Rachel Botting

Research Associate

Background

I studied Biomedical Science at the University of Technology of Sydney, during which I spent a year researching gene therapy targeting liver metabolic diseases at the Children’s Medical Research Institute. I undertook by PhD with the University of Sydney at the Westmead Institute, where I researched sexual transmission of HIV, specifically focusing on the involvement of cells found in the human anogenital tract. I’m currently working in the Haniffa lab at the Institute of Cellular Medicine, University of Newcastle, where I’m researching immunology and development of human skin.

Areas of expertise

  • Immunology
  • Virology
  • Development biology

Google scholar: Click here.

Publications

  • Botting RA, Rana H, Bertram KM, Rhodes JW, Baharlou H, Nasr N, Cunningham AL, Harman AN. Langerhans cells and sexual transmission of HIV and HSV. Reviews in Medical Virology 2017, 27(2), 1-10.
  • Harman AN, Nasr N, Feetham A, Galoyan A, Alshehri AA, Rambukwelle D, Botting RA, Hiener BM, Diefenbach E, Diefenbach RJ, Kim M, Mansell A, Cunningham AL. HIV Blocks Interferon Induction in Human Dendritic Cells and Macrophages by Dysregulation of TBK1. Journal of Virology 2015, 89(13), 6575-6584.
  • Nasr N, Lai J, Botting RA, Mercier SK, Harman AN, Kim M, Turville S, Center RJ, Domagala T, Gorry PR, Olbourne N, Cunningham AL. Inhibition of two temporal phases of HIV-1 transfer from primary Langerhans cells to T cells: the role of langerin. The Journal of Immunology 2014, 193(5), 2554-2564.
  • Harman AN, Bye CR, Nasr N, Sandgren KJ, Kim M, Mercier SK, Botting RA, Lewin SR, Cunningham AL, Cameron PU. Identification of lineage relationships and novel markers of blood and skin human dendritic cells. The Journal of Immunology 2013, 190(1), 66-79.
  • Mercier SK, Donaghy H, Botting RA, Turville SG, Harman AN, Nasr N, Ji H, Kusebauch U, Mendoza L, Shteynberg D, Sandgren K, Simpson RJ, Moritz RL, Cunningham AL. The microvesicle component of HIV-1 inocula modulates dendritic cell infection and maturation and enhances adhesion to and activation of T lymphocytes. PLOS Pathogens 2013, 9(10), e1003700.
  • Botting RA, McLachlan CS. Does cellular heterogeneity influence neuroblastoma cell line proliferation and invasiveness with granulocyte colony-stimulating factor?. Journal of Pediatric Surgery 2009, 44(12), 2436-2437.