Institute of Genetic Medicine

Stem cells, Regenerative and Reproductive Medicine

Stem cells, Regenerative and Reproductive Medicine

We are a large group of researchers with interests spanning stem cell biology, regeneration and reproduction.

Research

Our fields of interest and expertise extend from embryonic to adult stem cells, basic biology and clinical applications, creation of patient specific disease models, regenerative and reproductive medicine. Our key aim is to better understand and develop targeted therapies for eye, kidney, cardiac, endocrine and reproductive disorders.

With stem cell therapy related clinical trials underway, we have considerable expertise in both the regulatory aspects of cellular therapies and good manufacturing practice for the production of cells for transplantation.

Our Institute provides excellent facilities for stem cell research, including well equipped molecular biology laboratories, purpose made tissue culture suites, good manufacturing practice laboratories and stem cell specific bio-imaging and flow cytometry equipment. In reproductive medicine, we focus our basic research on understanding the genetic causes of male infertility using state-of-the-art genomics approaches, and our translational research on the development of approaches to prevent transmission of mitochondrial disease. 

Teaching

All the members of the Stem Cell, Regenerative and Reproductive medicine group at IGM deliver research-informed teaching and supervise laboratory-based research projects for undergraduate and post graduate students. The Masters by Research (MRes) and Academic Clinical Fellow programmes which are suitable for both science graduates and intercalating medical students are highlighted below:

Expertise

Principal investigatorArea of expertise
Prof. Lyle Armstrong Cellular reprogramming, otic regeneration, disease modelling and drug repurposing
Prof. Che Connon Tissue engineering and corneal biology
Prof. Nick Europe- Finner Cell signalling and epigenetics
Prof. Francisco Figueiredo Clinical trials of limbal stem cell deficiency, corneal biology and regeneration
Prof. David Elliott  RNA Biology, Genetics of male infertility, Alternative RNA processing in germ cell development, Meiosis
Prof. Mary Herbert Oogenesis, Preimplantation development
Prof. Majlinda Lako Corneal and retinal biology, stem cell differentiation to eye cells, clinical trials for eye disease, in situ gene editing and disease modelling
Dr. Annette Meeson Stem cells in cardiac development and regeneration
Dr. Colin Miles In vivo modelling of kidney disease
Dr. Salman Razvi Early-phase clinic trials of hormonal manipulation in cardiac disease, epidemiology and outcome of thyroid dysfunction.
Dr. Anna Mitchell Genetics of thyroid and adrenal disease, pathophysiology of thyroid eye disease
Prof. Simon Pearce  Genetics of thyroid and adrenal disease, pre-clinical studies and targeted therapies for endocrine disease
Dr. Tim Cheetham Early-phase studies of thyroid diseases in younger people
Prof. John Sayer Genetics of renal disease, pre-clinical studies and targeted therapies for kidney disease
Mr. David Steel  Disease modelling and targeted therapies for retinal disease
Prof. Joris Veltman Genetics of male infertility
Prof. Mike Taggart Cellular, tissue and organ remodelling

 

 

 

 

 

 

 

Staff

Kathleen Allinson
Research Technician

Email:
Telephone: +44 (0) 191 241 8671

Dr Bilal Alobaidi
Research Technician

Email:

Professor Lyle Armstrong
Professor of Cellular Reprogramming

Email:
Telephone: +44 (0) 191 241 8695

Dr Sanja Bojic
Research Associate

Email:
Telephone: +44 (0)191 2418817

Dr Timothy Cheetham
Reader in Paediatric Endocrinology

Email:
Telephone: +44 (0) 191 282 9562

Dr Valeria Chichagova
Associate Researcher

Dr Joseph Collin
Senior Research Associate

Email:
Telephone: +44 (0)191 241 8857

Professor Che Connon
Professor of Tissue Engineering

Email:
Telephone: T: 0191 241 8623 M: 0793 1093 063

Professor David Elliott
Professor of Genetics

Email:
Telephone: +44 (0) 191 241 8694

Professor Francisco Figueiredo
Honorary Clinical Professor

Email:
Telephone: +44 (0) 191 282 5582

Dr Earn Gan
Academic Clinical Lecturer

Dr Dean Hallam
Associate Researcher

Professor Mary Herbert
Professor of Reproductive Biology

Email:
Telephone: +44 (0) 191 213 8213

Hadeel Ismail
Research Technician

Tamanna Jeewon
Research Technician

Dr Marzena Kurzawa-Akanbi
Senior Research Associate

Email:
Telephone: +44 (0) 191 241 8818

Professor Majlinda Lako
Prof of Stem Cell Science

Email:
Telephone: +44 (0) 191 241 8688

Email:
Telephone: +44 (0) 191 241 8856

Dr Colin Miles
Senior Lecturer

Email:
Telephone: +44 (0) 191 241 8699

Dr Anna Mitchell
Academic Clinical Lecturer

Dr Elisa Molinari
Research Associate

Professor Simon Pearce
Prof of Endocrinology

Email:
Telephone: +44 (0) 191 241 8674

Dr Simon Ramsbottom
Kidney Research UK Post-doctoral Fellow

Email:
Telephone: +44 (0)191 241 8612

Dr Salman Razvi
Clinical Senior Lecturer/Consultant

Email:
Telephone: 0191 241 8838

Professor John Sayer
Clin Prof of Renal Medicine

Email:
Telephone: +44 (0) 191 241 8608

Emma Scott
Research Associate

Email:

Dr Harsh Sheth
Research Associate

Email:

Dr Shalabh Srivastava
Associate Clinical Lecturer

David Steel
Honorary Clinical Senior Lecturer

Email:
Telephone: +44 (0) 191 5699065

Julie Taggart
Research Technician

Email:
Telephone: +44 (0) 191 2418720

Professor Michael Taggart
Chair of Reproductive Sciences

Email:
Telephone: +44 (0191) 208 6988

Jack Thornton
Technician

Email:
Telephone: 0191 2418611

Dr Darin Zerti
Research Associate

PhD Students

Our current PhD students are as follows.....

StudentLead supervisor
Intisar Al-Alawi Prof John Sayer
Olla Al-Jaibaji Prof Che Connon
Ahzad Hadi Bin Ahmad Dr Colin Miles
Adriana Buskin Prof Majlinda Lako
Daniel Cooney Prof Mary Herbert
Laura Devlin Prof John Sayer
Ivo Djidrovski Prof Lyle Armstrong
Majed Felemban Prof Majlinda Lako
Elizabeth Harris Prof Majlinda Lako
Gerald Hysenaj Prof David Elliott
Minjin Jeong Prof Majlinda Lako
Taty Kamarudin Prof Majlinda Lako
David Lee Prof Lyle Armstrong
Karen Livermore  Prof David Elliott 
Kumara Mastrorosa  Prof Joris Veltman 
Martina Miotto  Prof Che Connon 
Catherine Napier  Prof Simon Pearce 
Raveen Sandher  Prof Mary Herbert 
Shalabh Srivastava  Prof John Sayer
Rachel Thompson  Prof David Elliott 
Thomas Volatier  Prof Che Connon 
Ludmila Volozonoka  Prof Joris Veltman 
Linlin Wang  Prof Mary Herbert 

Contact

Do you want to find out more about Stem cells, Regenerative and Reproductive Medicine?

Please contact theme representative Prof Majlinda Lako.