Institute of Genetic Medicine

Staff Profile

Dr Jennifer Munkley

Faculty Fellow

Background

Our research aims to exploit an important yet understudied group of sugar molecules (known as glycans) to improve the diagnosis and treatment of cancer. Glycans are found on the cell surface of and secreted by cancer cells and change dramatically in all types of cancer.

 

Glycans are involved in all stages of cancer progression and play key roles in tumour development, growth and invasion. However, the molecular details underlying these changes are poorly understood, and of the four fundamental building blocks of life (proteins, glycans, lipids and nucleic acids) glycans have been the least studied. 

 

Work in our group is funded by Prostate Cancer UK. We are investigating how glycans influence prostate cancer cell behaviour, testing if they can be targeted by new treatments, and seeing if we can detect them as part of a new non-invasive test to improve diagnosis.


Areas of expertise

  • Glycosylation in cancer
  • Prostate cancer

Editorial Board: Scientific Reports


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Publications