Institute of Genetic Medicine

Staff Profile

Dr Matthew Barter

Research Associate - Molecular Rheumatol

Background

Qualifications

BSc, Biochemistry, Newcastle University, 2000-2004.
PhD (MRC and FARNE), Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, 2004-2008.

Current Position

2017- . Dunhill Medical Trust Research Associate, Institute of Genetic Medicine, Newcastle University.

Previous Positions

2011-2016. Arthritis Research UK Research Associate, Institute of Cellular Medicine, Newcastle University.
2008-2011. Action Medical Research Associate, Institute of Cellular Medicine, Newcastle University.

Memberships

Member of the Biochemical Society, the British Society for Matrix Biology (BSMB) and Osteoarthritis Research Society International (OARSI).

Research

Research Interests

Epigenetic regulation in cartilage, skeleton development and osteoarthritis.

Current Work

Long non-coding RNAs (lncRNAs) in cartilage, chondrocyte development and osteoarthritis.

MicroRNAs (miRNAs) in osteoarthritis and cartilage development - in vivo, in vitro and in silico.

DNA methylation in mesenchymal stem cells, chondrogenesis and cartilage.

HDACs and histone modifications in chondrocyte development, cartilage, joints and osteoarthritis.

Esteem Indicators

Reviewer for Arthritis Research UK, Reumafonds, Netherlands Organisation for Scientific Research (NWO).

Reviewer for Annals of the Rheumatic Diseases (ARD), Arthritis & Rheumatology (A&R), Osteoarthritis and Cartilage (OAC), Connective Tissue Research, The Journal of Rheumatology, Epigenomics, Scientific Reports, Theranostics.

Funding

Co-PI (David Young PI):

Laser-micro-dissection followed by RNA-seq to identify novel microRNA targets during long bone growth; Newcastle University;

Delivery of microRNAs a therapeutic option in osteoarthritis; JGW Patterson Foundation; £62,000; 01/08/17-31/07/18.

The role of long non-coding RNAs in regulating chondrogenesis and osteoarthritis: A transgenic approach; JGW Patterson Foundation; £74,500; 01/09/15-31/12/17.

Defining the epigenome of joint cells; JGW Patterson Foundation; £16,000; 01/04/13-31/12/14.

The role of histone deacetylase 3 in arthritis; JGW Patterson Foundation; £58,000; 01/11/13-20/06/16.

Teaching

Supervision

PhD, mRes and BSc laboratory projects. 

Publications