Dr Claire Witham
- Email: email@example.com
- Address: Institute of Neuroscience
Henry Wellcome Building for Neuroecology
Newcastle upon Tyne
I am a MRC/Newcastle University joint funded research fellow primarily based at the MRC Centre for Macaques (CFM) in Wiltshire.
CFM is a breeding centre and supplies academic institutions in the UK with rhesus macaques for research. The monkeys are housed in matrilineal groups with one male, 3-10 females and their infants.
My role involves co-ordinating the scientific projects that take place at CFM and carrying out my own research in primate welfare.
Area of expertise
The main focus of my current research is to develop new methods for monitoring the welfare of primates used in research. There are two strands to my research; firstly to investigate the use of sleep as a potential measure of welfare and secondly to develop automated techniques for analysing behaviour in videos. This research includes monkeys at both the Centre for Macaques and Newcastle University.
Sleep and Nocturnal Behaviour
People suffering from conditions such as stress and depression frequently complain of disrupted sleep. However, the use of sleep and nocturnal behaviour for monitoring welfare in animals has been almost entirely neglected. By using infrared sensitive cameras and infrared lights I can monitor how well the monkeys sleep (sleep duration/frequency of waking), where they choose to sleep within their enclosures and see different nocturnal behaviours such as scratching, stretching and yawning. I am investigating how sleep changes in relation to welfare interventions and also the impact of group size and the presence of young infants has on sleep.
Automated Analysis of Behaviour
Video is a widely used method for collecting behaviour data. However analysing video data is time consuming and requires training of staff. This makes it impractical to use on a regular basis to monitor welfare. I am developing automated techniques to analyse videos; these include utilising techniques developed from computer vision including face detection and face recognition to identify individual monkeys.
Previous to my current appointment I was a neuroscientist based in the lab of Prof Stuart Baker at Newcastle. My research included investigating the functional role of oscillations in the sensorimotor system in both monkeys and humans.
- Witham CL, Baker SN. Coding of digit displacement by cell spiking and network oscillations in the monkey sensorimotor cortex. Journal of Neurophysiology 2012, 108(12), 3342-3352.
- Witham CL, Baker SN. Directional coherence disentangles causality within the sensorimotor loop, but cannot open the loop Reply. Journal of Physiology 2012, 590(10), 2531-2533.
- Fisher KM, Soteropoulos DS, Witham CL. The Motor Cortex and Descending Control of Movement. Advances in Clinical Neuroscience and Rehabilitation 2012, 11(6), 11-13.
- Witham CL, Riddle CN, Baker MR, Baker SN. Contributions of descending and ascending pathways to corticomuscular coherence in humans. Journal of Physiology 2011, 589(15), 3789-3800.
- Witham CL, Baker SN. Modulation and transmission of peripheral inputs in monkey cuneate and external cuneate nuclei. Journal of Neurophysiology 2011, 106(5), 2764-2775.
- Witham CL, Wang M, Baker SN. Corticomuscular coherence between motor cortex, somatosensory areas and forearm muscles in the monkey. Frontiers in Systems Neuroscience 2010, 4, 38.
- Witham CL. Automated face recognition of rhesus macaques. Journal of Neuroscience Methods 2018, 300, 157-165.
- Witham CL, Fisher KM, Edgley SA, Baker SN. Corticospinal Inputs to Primate Motoneurons Innervating the Forelimb from Two Divisions of Primary Motor Cortex and Area 3a. Journal of Neuroscience 2016, 36(9), 2605-2616.
- Witham CL, Baker SN. Information theoretic analysis of proprioceptive encoding during finger flexion in the monkey sensorimotor system. Journal of Neurophysiology 2015, 113(1), 295-306.