Staff Profile

My research aims to define the dynamics of endogenous RNA modifications during immunoinflammatory processes that will help us to better understand the physiological immune responses. My long-term goal is to provide novel prognostic/diagnostic and therapeutic platforms for immune-mediated inflammatory diseases (IMID), marked by derailed immunoinflammatory processes, such as autoimmune disorders, cardiovascular disease (e.g atherosclerosis), cancer, and other relevant pathological conditions.

I am an elected member of the American Heart Association's (AHA) Genomic & Precision Medicine Early Career Council.

My research work has received commendations by basic research councils' of UK, European and American non-profit organizations.

Further information:

ORCID: https://orcid.org/0000-0003-4144-4305 

Linkedin: https://www.linkedin.com/in/aikaterini-gatsiou-phd-ba677858/

Google Scholar: https://scholar.google.gr/citations?hl=de&user=teDmup0AAAAJ

Twitter: https://twitter.com/Aik_Gatsiou

Undergraduate student's training:

BGM3063: Biochemistry of Gene Expression module (Lecturer from winter 2023/24 semester and onwards)

BGM1002: Seminar Leader of Biochemistry module.

Every year, I co-supervise 2-4 undergraduate student's theses.

Postgraduate student's training:

MMB8018: MRes Biomolecular Research in Health and Disease (Lecturer from winter 2023/24 semester and onwards)

MMB8037: Cardiovascular Science in Health and Disease (Lecturer until winter 2021/2022 semester)

Every year, I co-supervise 1-2 MRes students theses work.

• Articles

  • Stamatelopoulos K, Mueller-Hennessen M, Georgiopoulos G, Lopez-Ayala P, Sachse M, Vlachogiannis NI, Sopova K, Delialis D, Bonini F, Patras R, Ciliberti G, Vafaie M, Biener M, Boeddinghaus J, Nestelberger T, Koechlin L, Tual-Chalot S, Kanakakis I, Gatsiou A, Katus H, Spyridopoulos I, Mueller C, Giannitsis E, Stellos K. Cathepsin S Levels and Survival Among Patients With Non-ST-Segment Elevation Acute Coronary Syndromes. Journal of the American College of Cardiology 2022, 80(10), 998-1010.
  • Gatsiou A, Sopova K, Tselepis A, Stellos K. Interleukin-17A Triggers the Release of Platelet-Derived Factors Driving Vascular Endothelial Cells toward a Pro-Angiogenic State. Cells 2021, 10(8), 1855.
  • Vlachogiannis NI, Tual-Chalot S, Zormpas E, Bonini F, Ntouros PA, Pappa M, Bournia V-K, Tektonidou MG, Souliotis VL, Mavragani CP, Stamatelopoulos K, Gatsiou A, Sfikakis PP, Stellos K. Adenosine-to-inosine RNA editing contributes to type I interferon responses in systemic sclerosis. Journal of Autoimmunity 2021, 125, 102755.
  • Vlachogiannis NI, Sachse M, Georgiopoulos G, Zormpas E, Bampatsias D, Delialis D, Bonini F, Galyfos G, Sigala F, Stamatelopoulos K, Gatsiou A, Stellos K. Adenosine-to-inosine Alu RNA editing controls the stability of the pro-inflammatory long noncoding RNA NEAT1 in atherosclerotic cardiovascular disease. Journal of Molecular and Cellular Cardiology 2021, 160, 111-120.
  • Gatsiou A, Georgiopoulos G, Vlachogiannis NI, Pfisterer L, Fischer A, Sachse M, Laina A, Bonini F, Delialis D, Tual-Chalot S, Zormpas E, Achangwa R, Jiang L, Kontogiannis C, Patras R, Hermeking H, Zeiher AM, Stamatelopoulos K, Dimmeler S, Stellos K. Additive contribution of microRNA-34a/b/c to human arterial ageing and atherosclerosis. Atherosclerosis 2021, 327, 49-58.
  • Vlachogiannis NI, Gatsiou A, Silvestris DA, Stamatelopoulos K, Tektonidou MG, Gallo A, Sfikakis PP, Stellos K. Increased adenosine-to-inosine RNA editing in rheumatoid arthritis. Journal of Autoimmunity 2020, 106, 102329.
  • Stamatelopoulos K, Georgiopoulos G, Athanasouli F, Nikolaou P-E, Lykka M, Roussou M, Gavriatopoulou M, Laina A, Trakada G, Charakida M, Delialis D, Petropoulos I, Pamboukas C, Manios E, Karakitsou M, Papamichael C, Gatsiou A, Lambrinoudaki I, Terpos E, Stellos K, Andreadou I, Dimopoulos MA, Kastritis E. Reactive Vasodilation Predicts Mortality in Primary Systemic Light-Chain Amyloidosis. Circulation Research 2019, 125(8), 744-758.
  • Gatsiou A, Stellos K. Dawn of Epitranscriptomic Medicine. Circulation: Genomic and Precision Medicine 2018, 11(9), e001927.
  • Stamatelopoulos K, Mueller-Hennessen M, Georgiopoulos G, Sachse M, Boeddinghaus J, Sopova K, Gatsiou A, Amrhein C, Biener M, Vafaie M, Athanasouli F, Stakos D, Pateras K, Twerenbold R, Badertscher P, Nestelberger T, Dimmeler S, Katus HA, Zeiher AM, Mueller C, Giannitsis E, Stellos K. Amyloid-ß (1-40) and Mortality in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome: A Cohort Study. Annals of Internal Medicine 2018, 168(12), 855-865.
  • Stellos K, Gatsiou A, Stamatelopoulos K, Perisic Matic L, John D, Lunella FF, Jae N, Rossbach O, Amrhein C, Sigala F, Boon RA, Furtig B, Manavski Y, You X, Uchida S, Keller T, Boeckel J-N, Franco-Cereceda A, Maegdefessel L, Chen W, Schwalbe H, Bindereif A, Eriksson P, Hedin U, Zeiher AM, Dimmeler S. Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation. Nature Medicine 2016, 22(10), 1140-1150.
  • Stamatelopoulos K, Sibbing D, Rallidis LS, Georgiopoulos G, Stakos D, Braun S, Gatsiou A, Sopova K, Kotakos C, Varounis C, Tellis CC, Kastritis E, Alevizaki M, Tselepis AD, Alexopoulos P, Laske C, Keller T, Kastrati A, Dimmeler S, Zeiher AM, Stellos K. Amyloid-beta (1-40) and the risk of death from cardiovascular causes in patients with coronary heart disease. Journal of the American College of Cardiology 2015, 65(9), 904-916.

• Letter

  • Mareti A, Kritsioti C, Georgiopoulos G, Vlachogiannis NI, Delialis D, Sachse M, Sopova K, Koutsoukis A, Kontogiannis C, Patras R, Tual-Chalot S, Koureas A, Gatsiou A, Stellos K, Stamatelopoulos K. Cathepsin B expression is associated with arterial stiffening and atherosclerotic vascular disease. European Journal of Preventive Cardiology 2019, 27(19), 2288-2291.

• Review

  • Laina A, Gatsiou A, Georgiopoulos G, Stamatelopoulos K, Stellos K. RNA therapeutics in cardiovascular precision medicine. Frontiers in Physiology 2018, 9, 953.