I have a strong interest and great enthusiasm for methodological research to improve efficiency of clinical trials.

From 2015 to 2018, I was appointed as a Marie Skłodowska-Curie ITN research fellow in the IDEAS network and completed my PhD at Lancaster University. My PhD research was about Bayesian adaptive methods to incorporate preclinical data into phase I clinical trials, supervised by Dr Lisa Hampson and Professor Thomas Jaki.

I joined Newcastle University in October 2018. I am now working with Professor James Wason on Bayesian adaptive methods for basket trials.

I am part of the PHSI Biostatistics Research Group.

Google scholar: click here.

Topics falling under the general remit of medical statistics are interesting to me. To be more specific, I found

(1) Bayesian adaptive designs,

(2) early phase dose-finding trials, and

(3) data augmentation techniques for trials with a small sample size

are particularly fascinating. 

I am open to new collaborations with both academia and pharmaceutical industry -- very much look forward to solving more problems relating to (but not limited to) the topics listed above.

I have been invited to develop and deliver several tutorials on

(1) Statistical Methods for Design and Analysis of Precision Medicine Trials, 24th & 25th March 2020

• A short-course for postgraduates, statisticians and professionals who run clinical trials
• Course information: click here
• Host: MRC Biostatistics Unit, University of Cambridge

(2) Design and Analysis of Clinical Trials in the Era of Precision Medicine, 6th October 2019

• A pre-conference educational workshop at ICTMC 2019

(3) Bayesian Statistics with Applications in Clinical Trials, 5th & 6th September 2019

• A short-course for postgraduates and professionals who work in clinical research
• Host: Department of Medical Statistics, Osaka City University (Japan)

• Zheng H, Jaki T, Wason JMS. Bayesian sample size determination using commensurate priors to leverage pre-experimental data. 2020. Submitted.
• Grayling MJ, Bigirumurame T, Cherlin S, Ouma L, Zheng H, Wason JMS. Innovative trial approaches in immune-mediated inflammatory diseases: current use and future potential. 2020. Submitted.
• Ouma L, Grayling MJ, Zheng H, Wason JMS. Treatment allocation strategies for umbrella trials in the presence of multiple biomarkers: a comparison of methods. 2020. Submitted.
• Zhu J, Zheng H, Li Y, Wang T, Zhong Y, Fan C, Li Y. Adipokines and risk of rheumatoid arthritis: a Mendelian randomization study. 2020. Submitted.
• Zheng H, Hampson LV, Jaki T. Bridging across patient subgroups in phase I oncology trials that incorporate animal data. 2020. Submitted.
• Zheng H, Wason JMS. Borrowing of information across patient subgroups in a basket trial based on distributional discrepancy. Biostatistics 2020, ePub ahead of print.
• Xie X, Lv D, Zheng H, Zhang X, Han F, Chen J. The associations of blood pressure parameters with all-cause and cardiovascular mortality in peritoneal dialysis patients: a cohort study in China. Journal of Hypertension 2020, epub ahead of print.
• Zheng H, Hampson LV. A Bayesian decision-theoretic approach to incorporate preclinical information into phase I oncology trials. Biometrical Journal 2020, epub ahead of print.
• Zheng H, Hampson LV, Wandel S. A robust Bayesian meta-analytic approach to incorporate animal data into phase I oncology trials. Statistical Methods in Medical Research 2020, 29(1), 94-110.
• Zheng H. Bayesian Adaptive Methods to Incorporate Preclinical Data into Phase I Clinical Trials [PhD Thesis]. Lancaster, UK: Lancaster University, 2019.
• Luo M, Zheng H, Zhang Y, Feng Y, Li D, Li X, Han J, Li T. A nomogram for predicting the likelihood of obstructive sleep apnea to reduce the unnecessary polysomnography examinations. Chinese Medical Journal 2015, 128(16), 2134-2140.
• Tada S, Allen PF, Ikebe K, Zheng H, Shintani A, Maeda Y. The Impact of the crown-root ratio on survival of abutment teeth for dentures. Journal of Dental Research 2015, 94(9 suppl), 220S-225S.