Staff Profile
Dr Haiyan Zheng
Research Associate (Statistician)
- Email: haiyan.zheng@ncl.ac.uk
- Telephone: +44 (0) 191 208 5006
- Address: Population Health Sciences Institute, Newcastle University
Level 4, Baddiley-Clark Building, Richardson Road, Newcastle upon Tyne, NE2 4AX, UK
I have a strong interest and great enthusiasm for methodological research to improve efficiency of clinical trials.
From 2015 to 2018, I was appointed as a Marie Skłodowska-Curie ITN research fellow in the IDEAS network and completed my PhD at Lancaster University. My PhD research was about Bayesian adaptive methods to incorporate preclinical data into phase I clinical trials, supervised by Dr Lisa Hampson and Professor Thomas Jaki.
I joined Newcastle University in October 2018. I am now working with Professor James Wason on Bayesian adaptive methods for basket trials.
I am part of the PHSI Biostatistics Research Group.
Google scholar: click here.
Topics falling under the general remit of medical statistics are interesting to me. To be more specific, I found
(1) Bayesian adaptive designs,
(2) early phase dose-finding trials, and
(3) data augmentation techniques for trials with a small sample size
are particularly fascinating.
I am open to new collaborations with both academia and pharmaceutical industry -- very much look forward to solving more problems relating to (but not limited to) the topics listed above.
I have been invited to develop and deliver several tutorials on
(1) Statistical Methods for Design and Analysis of Precision Medicine Trials, 24th & 25th March 2020
- A short-course for postgraduates, statisticians and professionals who run clinical trials
- Course information: click here
- Host: MRC Biostatistics Unit, University of Cambridge
(2) Design and Analysis of Clinical Trials in the Era of Precision Medicine, 6th October 2019
- A pre-conference educational workshop at ICTMC 2019
(3) Bayesian Statistics with Applications in Clinical Trials, 5th & 6th September 2019
- A short-course for postgraduates and professionals who work in clinical research
- Host: Department of Medical Statistics, Osaka City University (Japan)
- Zheng H, Jaki T, Wason JMS. Bayesian sample size determination using commensurate priors to leverage pre-experimental data. 2020. Submitted.
- Grayling MJ, Bigirumurame T, Cherlin S, Ouma L, Zheng H, Wason JMS. Innovative trial approaches in immune-mediated inflammatory diseases: current use and future potential. 2020. Submitted.
- Ouma L, Grayling MJ, Zheng H, Wason JMS. Treatment allocation strategies for umbrella trials in the presence of multiple biomarkers: a comparison of methods. 2020. Submitted.
- Zhu J, Zheng H, Li Y, Wang T, Zhong Y, Fan C, Li Y. Adipokines and risk of rheumatoid arthritis: a Mendelian randomization study. 2020. Submitted.
- Zheng H, Hampson LV, Jaki T. Bridging across patient subgroups in phase I oncology trials that incorporate animal data. Statistical Methods in Medical Research 2021, Epub ahead of print.
- Zheng H, Wason JMS. Borrowing of information across patient subgroups in a basket trial based on distributional discrepancy. Biostatistics 2020, ePub ahead of print.
- Xie X, Lv D, Zheng H, Zhang X, Han F, Chen J. The associations of blood pressure parameters with all-cause and cardiovascular mortality in peritoneal dialysis patients: a cohort study in China. Journal of Hypertension 2020, 38(11), 2252-2260.
- Zheng H, Hampson LV. A Bayesian decision‐theoretic approach to incorporate preclinical information into phase I oncology trials. Biometrical Journal 2020, 62(6), 1408-1427.
- Zheng H, Hampson LV, Wandel S. A robust Bayesian meta-analytic approach to incorporate animal data into phase I oncology trials. Statistical Methods in Medical Research 2020, 29(1), 94-110.
- Zheng H. Bayesian Adaptive Methods to Incorporate Preclinical Data into Phase I Clinical Trials [PhD Thesis]. Lancaster, UK: Lancaster University, 2019.
- Luo M, Zheng H, Zhang Y, Feng Y, Li D, Li X, Han J, Li T. A nomogram for predicting the likelihood of obstructive sleep apnea to reduce the unnecessary polysomnography examinations. Chinese Medical Journal 2015, 128(16), 2134-2140.
- Tada S, Allen PF, Ikebe K, Zheng H, Shintani A, Maeda Y. The Impact of the crown-root ratio on survival of abutment teeth for dentures. Journal of Dental Research 2015, 94(9 suppl), 220S-225S.