I am a Public Engagement Officer working within the Wellcome Centre for Mitochondrial Research. I studied within the department for a Master’s in research and subsequently for a PhD investigating exercise therapy to treat patients with Mitochondrial Myopathy. In 2013 I moved from laboratory work to take up an engagement role within the Centre. My main passion is patient care, engagement and empowerment. I feel privileged to work within the mitochondrial patient community and hope that through engagement activities I can make the sometimes complex mitochondrial science more accessible to patients, their families and the general public.  

• Craven L, Murphy J, Turnbull DM, Taylor RW, Gorman GS, McFarland R. Scientific and Ethical Issues in Mitochondrial Donation. New Bioethics 2018, 24(1), 57-73.
• Craven L, Herbert M, Murdoch A, Murphy J, Davies JL, Turnbull DM. Research into Policy: A Brief History of Mitochondrial Donation. Stem Cells 2016, 34(2), 265-267.
• Grady JP, Murphy JL, Blakely EL, Haller RG, Taylor RW, Turnbull DM, Tuppen HAL. Accurate Measurement of Mitochondrial DNA Deletion Level and Copy Number Differences in Human Skeletal Muscle. PLoS One 2014, 9(12), e114462.
• Pfeffer G, Gorman GS, Griffin H, Kurzawa-Akanbi M, Blakely EL, Wilson I, Sitarz K, Moore D, Murphy JL, Alston CL, Pyle A, Coxhead J, Payne B, Gorrie GH, Longman C, Hadjivassiliou M, McConville J, Dick D, Imam I, Hilton D, Norwood F, Baker MR, Jaiser SR, Yu-Wai-Man P, Farrell M, McCarthy A, Lynch T, McFarland R, Schaefer AM, Turnbull DM, Horvath R, Taylor RW, Chinnery PF. Mutations in the SPG7 gene cause chronic progressive external ophthalmoplegia through disordered mitochondrial DNA maintenance. Brain 2014, 137(5), 1323-1336.
• Spendiff S, Reza M, Murphy JL, Gorman G, Blakely EL, Taylor RW, Horvath R, Campbell G, Newman J, Lochmüller H, Turnbull DM. Mitochondrial DNA deletions in muscle satellite cells: implications for therapies. Human Molecular Genetics 2013, 22(23), 4739-4747.
• Ratnaike TE, Murphy J, Krishnan KJ, Taylor RW, Turnbull DM. Changes in mitochondrial function over time and with exercise in patients with mitochondrial disease. In: United Kingdom Neuromuscular Translational Research Conference. 2012, Newcastle upon Tyne, UK: Elsevier Ltd.
• Murphy JL, Ratnaike TE, Shang ES, Falkous G, Blakely EL, Alston CL, Taivassalo T, Haller RG, Taylor RW, Turnbull DM. Cytochrome c oxidase-intermediate fibres: Importance in understanding the pathogenesis and treatment of mitochondrial myopathy. Neuromuscular Disorders 2012, 22(8), 690-698.
• Krishnan KJ, Nelson G, Romero NB, Ratnaike T, Blakely EL, Ziyadeh-Isleem A, Miller J, Murphy JL, Horvath R, Lochmuller H, Flanigan K, Turnbull DM, Guicheney P, Bitoun M, Taylor RW. DNM2 mutations cause multiple mtDNA deletions in muscle: A novel disorder of mtDNA maintenance. In: 17th International Congress of the World Muscle Society (WMS). 2012, Perth, Australia: Elsevier Ltd.
• Murphy JL, Ratnaike TE, Shang E, Falkous G, Blakely EL, Alston CL, Hickman K, Chanter H, Taivassalo T, Haller RG, Taylor RW, Turnbull DM. Long term endurance training and deconditioning in patients with mitochondrial myopathy. In: United Kingdom Neuromuscular Translational Research Conference. 2012, Newcastle upon Tyne, UK: Elsevier Ltd.
• Murphy JL, Newman J, Ratnaike TE, Spendiff S, Falkous G, Blakely EL, Alston CL, Taylor RW, Trenell MI, Gorman GS, Turnbull DM. Resistance training in patients with mitochondrial myopathy. In: United Nations Environment Programme, Mineral Resources Forum. 2012, Newcastle upon Tyne, UK: Elsevier Ltd.
• Murphy JL, Shang E, Taivassalo T, Haller RG, Taylor RW, Turnbull DM. Exercise training in patients with mitochondrial myopathy: the analysis of COX-intermediate fibres. In: Neuromuscular Disorders: United Kingdom Neuromuscular Translational Research Conference. 2011, London, UK: Elsevier Ltd.
• Spendiff S, Horvath R, Lochmüller H, Reza M, Murphy JL, Taylor RW, Turnbull DM. Mitochondrial DNA mutations in satellite cells. In: UK Neuromuscular Translational Research Conference. 2011, London: Neuromuscular Disorders: Pergamon.
• Spendiff S, Horvath R, Murphy JL, Taylor RW, Reza M, Lochmuller H, Turnbull DM. Finding the missing gap - mitochondrial DNA deletions in muscle stem cells. In: United Kingdom Neuromuscular Translational Research Conference 2010. 2010, Oxford: Neuromuscular Disorders, Elsevier.
• Craven L, Tuppen HA, Greggains GD, Harbottle SJ, Murphy JL, Cree LM, Murdoch AP, Chinnery PF, Taylor RW, Lightowlers RN, Herbert M, Turnbull DM. Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease. Nature 2010, 465(7294), 82-85.
• Mahad DJ, Ziabreva I, Campbell G, Laulund F, Murphy JL, Reeve AK, Greaves L, Smith KJ, Turnbull DM. Detection of cytochrome c oxidase activity and mitochondrial proteins in single cells. Journal of Neuroscience Methods 2009, 184(2), 310-319.
• Murphy JL, Charlton R, Barresi R, Bushby KM, Taylor RW, Turnbull DM. G.P.10.09 Mitochondrial dysfunction in dysferlinopathy. In: Neuromuscular Disorders: 13th International Congress of the World Muscle Society. 2008, Newcastle upon Tyne, UK: Elsevier.
• Murphy JL, Blakely EL, Schaefer AM, He L, Wyrick P, Haller RG, Taylor RW, Turnbull DM, Taivassalo T. Resistance training in patients with single, large-scale deletions of mitochondrial DNA. Brain 2008, 131(11), 2832-2840.
• Thomson RG, Gani A, Dobson R, Herd B, Murphy J, James O, Rodgers H. The Tees Stroke Register: stroke incidence in an area of high stroke mortality. In: 8th European Stroke Conference. 1999, Venice, Italy: S. Karger AG.