Staff Profile
Dr Matthew Wilcox
Publications
-
Articles
- Houghton D, Shannon OM, Chater PI, Wilcox MD, Pearson J, Stanforth K, Jordan C, Avery L, Blain AP, Joel A, Jeffers R, Nolan R, Nelson A, Stewart CJ, Malcomson FC. White kidney bean extract as a nutraceutical: Effects on gut microbiota, alpha-amylase inhibition, and user experiences. Gut Microbiome 2023, Epub ahead of print.
- Wilcox MD, Chater PI, Stanforth KJ, Woodcock AD, Dettmar PW, Pearson JP. The rheological properties of an alginate satiety formulation in a physiologically relevant human model gut system. Annals of Esophagus 2022, 5, 3.
- Al-Momani H, Perry A, Nelson A, Stewart CJ, Jones R, Krishnan A, Robertson A, Bourke S, Doe S, Cummings S, Anderson A, Forrest T, Forrest I, Griffin M, Wilcox M, Brodlie M, Pearson J, Ward C. Exposure to bile and gastric juice can impact the aerodigestive microbiome in people with cystic fibrosis. Scientific Reports 2022, 12(1), 11114.
- Wilcox MD, Chater PI, Stanforth KJ, Williams R, Brownlee IA, Pearson JP. A Pilot Pre and Post 4 Week Intervention Evaluating the Effect of a Proprietary, Powdered, Plant Based Food on Micronutrient Status, Dietary Intake, and Markers of Health in a Healthy Adult Population. Frontiers in Nutrition 2022, 9, 945622.
- Wilcox MD, Cherry P, Chater PI, Yang X, Zulali M, Okello EJ, Seal CJ, Pearson JP. The effect of seaweed enriched bread on carbohydrate digestion and the release of glucose from food. Journal of Functional Foods 2021, 87, 104747.
- Inchaurraga L, Martinez-Lopez AL, Cattoz B, Griffiths PC, Wilcox M, Pearson JP, Quincoces G, Penuelas I, Martin-Arbella N, Irache JM. The effect of thiamine-coating nanoparticles on their biodistribution and fate following oral administration. European Journal of Pharmaceutical Sciences 2019, 128, 81-90.
- Arriola NDA, Chater PI, Wilcox MD, Lucinic L, Rocchettic G, Dalminad M, Pearson JP, Amboni RDdeMC. Encapsulation of stevia rebaudiana Bertoni aqueous crude extracts by ionic gelation – Effects of alginate blends and gelling solutions on the polyphenolic profile. Food Chemistry 2019, 275, 123-134.
- Houghton d, Wilcox MD, Brownlee IA, Chater PI, Seal CJ, Pearson JP. Acceptability of alginate enriched bread and its effect on fat digestion in humans. Food Hydrocolloids 2019, 93, 395-401.
- Gill S, Chater PI, Wilcox MD, Pearson JP, Brownlee IA. The impact of dietary fibres on the physiological processes of the large intestine. Bioactive Carbohydrates and Dietary Fibre 2018, 16, 62-74.
- Bakshani CR, Morales-Garcia AL, Althaus M, Wilcox MD, Pearson JP, Bythell JC, Burgess G. Evolutionary conservation of the antimicrobial function of mucus: a first defence against infection. npj Biofilms and Microbiomes 2018, 4(14), 1-12.
- Chater PI, Wilcox MD, Pearson JP. Efficacy and safety concerns over the use of mucus modulating agents for drug delivery using nanoscale systems. Advanced Drug Delivery Reviews 2018, 124, 184-192.
- Prufert F, Bonengel S, Kollner S, Griesser J, Wilcox MD, Chater PI, Pearson JP, Bernkop-Schnurch A. ζ potential changing nanoparticles as cystic fibrosis transmembrane conductance regulator gene delivery system: An in vitro evaluation. Nanomedicine 2017, 12(22), 2713-2724.
- Iglesias T, de Cerain AL, Irache JM, Martin-Arbella N, Wilcox M, Pearson J, Azqueta A. Evaluation of the cytotoxicity, genotoxicity and mucus permeation capacity of several surface modified poly(anhydride) nanoparticles designed for oral drug delivery. International Journal of Pharmaceutics 2017, 517(1-2), 67-79.
- Chater PI, Wilcox M, Cherry P, Herford A, Mustar S, Wheater H, Brownlee I, Seal C, Pearson J. Inhibitory activity of extracts of Hebridean brown seaweeds on lipase activity. Journal of Applied Phycology 2016, 28(2), 1303-1313.
- Wilcox MD, Van Rooij LK, Chater PI, de Sousa IP, Pearson JP. The effect of nanoparticle permeation on the bulk rheological properties of mucus from the small intestine. European Journal of Pharmaceutics and Biopharmaceutics 2015, 96, 484-487.
- Oh S, Wilcox M, Pearson JP, Borros S. Optimal design for studying mucoadhesive polymers interaction with gastric mucin using a quartz crystal microbalance with dissipation (QCM-D): Comparison of two different mucin origins. European Journal of Pharmaceutics and Biopharmaceutics 2015, 96, 477-483.
- Pereira De Sousa I, Cattoz B, Wilcox MD, Griffiths PC, Dalgliesh R, Rogers S, Bernkop-Schnurch A. Nanoparticles decorated with proteolytic enzymes, a promising strategy to overcome the mucus barrier. European Journal of Pharmaceutics and Biopharmaceutics 2015, 97(Part A), 257-264.
- de Sousa IP, Steiner C, Schmutzler M, Wilcox MD, Veldhuis GJ, Pearson JP, Huck CW, Salvenmoser W, Bernkop-Schnurch A. Mucus permeating carriers: formulation and characterization of highly densely charged nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics 2015, 97(Part A), 273-279.
- Houghton D, Wilcox MD, Chater PI, Brownlee IA, Seal CJ, Pearson JP. Biological activity of alginate and its effect on pancreatic lipase inhibition as a potential treatment for obesity. Food Hydrocolloids 2015, 49, 18-24.
- Chater PI, Wilcox MD, Brownlee IA, Pearson JP. Alginate as a protease inhibitor in vitro and in a model gut system; selective inhibition of pepsin but not trypsin. Carbohydrate Polymers 2015, 131, 142-151.
- Wilcox MD, Brownlee IA, Richardson J, Dettmar PW, Pearson JP. The modulation of pancreatic lipase activity by alginates. Food Chemistry 2014, 146, 479-484.
- Houghton D, Wilcox MD, Brownlee IA, Chater P, Seal CJ, Pearson JP. Method for quantifying alginate and determining release from a food vehicle in gastrointestinal digesta. Food Chemistry 2014, 151, 352-357.
- Balasubramaniam V, Mustar S, Mustafa Khalid N, Abd Rashed A, Mohd Noh MF, Wilcox MD, Chater PI, Brownlee IA, Pearson JP. Inhibitory activities of three Malaysian edible seaweeds on lipase and α-amylase. Journal of Applied Phycology 2013, 25(5), 1405-1412.
- Friedl H, Dünnhaupt S, Hintzen F, Waldner C, Parikh S, Pearson JP, Wilcox MD, Bernkop-Schnürch A. Development and Evaluation of a Novel Mucus Diffusion Test System Approved by Self-Nanoemulsifying Drug Delivery Systems. Journal of Pharmaceutical Sciences 2013, 102(12), 4406-4413.
-
Book Chapter
- Brownlee IA, Seal CJ, Wilcox M, Dettmar PW, Pearson JP. Applications of Alginates in Food. In: Rehm, BHA, ed. Alginates: Biology and applications. Berlin, Germany: Springer, 2009, pp.211-228.
-
Conference Proceedings (inc. Abstracts)
- Houghton D, Chater P, Wilcox M, Brownlee I, Trenell MI, Seal C, Pearson J. Alginate enriched bread attenuates circulating lipids and non-alcoholic fatty liver disease. In: 50th Annual Meeting of the European Association for the Study of the Liver. 2015, Vienna, Austria: Elsevier.
- Chater PI, Wilcox M, Brownlee I, Pearson JP. A synthetic model gut system to study macronutrient digestion in vitro. In: Proceedings of the Nutrition Society: Summer Meeting 2014. 2015, Cambridge University Press.
-
Letter
- Dettmar PW, Woodcock AD, Wilcox MD, Chater PI, Pearson JP. Letter: studies of salivary pepsin in patients with gastro-oesophageal reflux disease. Alimentary Pharmacology and Therapeutics 2019, 49(9), 1248-1249.
-
Reviews
- Stanforth K, Chater P, Brownlee I, Wilcox M, Ward C, Pearson J. In vitro modelling of the mucosa of the oesophagus and upper digestive tract: narrative review. Annals of Esophagus 2022, 5, 4.
- Brownlee IA, Gill S, Wilcox MW, Pearson JP, Chater PI. Starch digestion in the upper gastrointestinal tract of humans. Starch 2018, 70(9-10), 1700111.
- Brownlee IA, Chater PI, Pearson JP, Wilcox MD. Dietary fibre and weight loss: Where are we now?. Food Hydrocolloids 2017, 68, 186-191.
- Pearson JP, Chater PI, Wilcox MD. The properties of the mucus barrier, a unique gel - how can nanoparticles cross it?. Therapeutic Delivery 2016, 7(4), 229-244.
- Chater PI, Wilcox MD, Houghton D, Pearson JP. The role of seaweed bioactives in the control of digestion: implications for obesity treatments. Food & Function 2015, 6(11), 3420-3427.
- Chater PI, Wilcox MD, Pearson JP, Brownlee IA. The impact of dietary fibres on the physiological processes governing small intestinal digestive processes. Bioactive Carbohydrates and Dietary Fibre 2015, 6(2), 117-132.
- Brownle IA, Forster DJ, Wilcox MD, Dettmar PW, Seal CJ, Pearson JP. Physiological parameters governing the action of pancreatic lipase. Nutrition Research Reviews 2010, 23, 146-154.