I completed a BSc in Biology (Minor in Chemistry with Distinction) at the College of the Bahamas in 2012 and went on to complete a Masters by Research in Immunobiology at Newcastle University in 2014. 

I completed my PhD in Molecular Biochemistry in the lab of Professor Derek Mann at Newcastle University. My project involved understanding the structural basis of the interaction between NF-κB subunit p50 and Histone Deacetylase 1 and how this interaction mediates the inflammatory response.

In my current role I am a molecular biologist in Professor Jonathan Higgins' Lab working to understand the kinases responsible for and the role of phosphorylation events in mitosis alongside developing a method to identify kinases responsible for known important sites of phosphorylation.   

BGM1004 - Genetics 

MMB8008 - Cell Cycle Control and Cell Signalling in Health and Disease 

In my role as a Research Associate I have supervised a number of BSc final year student projects.

• Worrell J, Leslie J, Smith GR, Zaki M, Paish H, Knox A, James ML, Cartwright TN, OReily S, Kania G, Distler O, Distler J, Herrick A, Jeziorska M, Borthwick LA, Fisher AJ, Mann J, Mann DA, Oakley F. cRel expression regulates distinct transcriptional and functional profiles driving fibroblast matrix production in systemic sclerosis. Rheumatology 2020, epub ahead of print.
• Watson NA, Cartwright TN, Lawless C, Cámara-Donoso M, Sen O, Sako K, Hirota T, Kimura H, Higgins JMG. Kinase inhibition profiles as a tool to identify kinases for specific phosphorylation sites. Nature Communications 2020, 11, 1684.
• Cartwright TN, Worrell JC, Marchetti L, Dowling CM, Knox A, Kiely P, Mann J, Mann DA, Wilson CL. HDAC1 interacts with the p50 NF-κB subunit via its nuclear localization sequence to constrain inflammatory gene expression. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 2018, 1861(10), 962-970.
• Cartwright T, Perkins ND, Wilson CL. NFKB1: a suppressor of inflammation, ageing and cancer. FEBS Journal 2016, 283(10), 1812-1822.