Staff Profile
Dr Yoshiki Hase
Research Associate
- Email: yoshiki.hase@ncl.ac.uk
- Telephone: +44 (0) 191 208 1218
- Fax: +44 (0) 191 208 1301
- Address: Translational and Clinical Research Institute
Edwardson Building,
Newcastle University,
Campus for Ageing and Vitality,
Newcastle upon Tyne,
NE4 5PL,
United Kingdom
Publications
- Yamamoto Y, Hase Y, Ihara M, Khundakar A, Roeber S, Duering M, Kalaria RN. Neuronal densities and vascular pathology in the hippocampal formation in CADASIL. Neurobiology of Aging 2021, 97, 33-40.
- Panahi M, Rodriguez PR, Fereshtehnejad S-M, Arafa D, Bogdanovic N, Winblad B, Cedazo-Minguez A, Rinne J, Darreh-Shori T, Hase Y, Kalaria RN, Viitanen M, Behbahani H. Insulin-Independent and Dependent Glucose Transporters in Brain Mural Cells in CADASIL. Frontiers in Genetics 2020, 11, 1022.
- Stevenson W, Hase Y, Wilson E, Hollins A, Hase M, Ennaceur A, Craggs L, Ihara M, Horsburgh K, Kalaria RN. Long-term effects of experimental carotid stenosis on hippocampal infarct pathology, neurons and glia and amelioration by environmental enrichment. Brain Research Bulletin 2020, 163, 72-83.
- Ding R, Hase Y, Ameen-Ali KE, Ndung'u M, Stevenson W, Barsby J, Gourlay R, Akinyemi T, Akinyemi R, Uemura MT, Polvikoski T, Mukaetova-Ladinska E, Ihara M, Kalaria RN. Loss of capillary pericytes and the blood–brain barrier in white matter in poststroke and vascular dementias and Alzheimer’s disease. Brain Pathology 2020, 30(6), 1087-1101.
- Hase Y, Polvikoski TM, Firbank MJ, Craggs LJL, Hawthorne E, Platten C, Stevenson W, Deramecourt V, Ballard C, Kenny RA, Perry RH, Ince P, Carare RO, Allan LM, Horsburgh K, Kalaria RN. Small vessel disease pathological changes in neurodegenerative and vascular dementias concomitant with autonomic dysfunction. Brain Pathology 2020, 30(1), 191-202.
- Rajani RM, Ratelade J, Domenga-Denier V, Hase Y, Kalimo H, Kalaria RN, Joutel A. Blood brain barrier leakage is not a consistent feature of white matter lesions in CADASIL. Acta Neuropathologica Communications 2019, 7, 187.
- Gallart-Palau X, Serra A, Hase Y, Tan CF, Chen CP, Kalaria RN, Sze SK. Brain-derived and circulating vesicle profiles indicate neurovascular unit dysfunction in early Alzheimer’s disease. Brain Pathology 2019, 29(5), 593-605.
- Kalaria RN, Hase Y. Neurovascular Ageing and Age-Related Diseases. In: J. Robin Harris and Viktor I. Korolchuk, ed. Biochemistry and Cell Biology of Ageing: Part II Clinical Science. Singapore: Springer, 2019, pp.477-499.
- Kalaria RN, Hase Y, Ihara M. The rise and rise of cerebral small vessel disease: Implications for vascular cognitive impairment and dementia. Future Neurology 2019, 14(2), 1-4.
- Hase Y, Ding R, Harrison G, Hawthorne E, King A, Gettings S, Platten C, Stevenson W, Craggs LJL, Kalaria RN. White matter capillaries in vascular and neurodegenerative dementias. Acta Neuropathologica Communications 2019, 7(1), 16.
- Nakaoku Y, Oishi N, Hase Y, Hase M, Saito S, Mitsueda T, Matsui M, Toyoda K, Nagatsuka K, Kalaria RN, Fukuyama H, Ihara M, Takahashi R. Montreal Cognitive Assessment score correlates with regional cerebral blood flow in post-stroke patients. Clinical Neurology and Neurosurgery 2018, 174, 68-74.
- Hase Y, Chen A, Bates LL, Craggs LJL, Yamamoto Y, Gemmell E, Oakley AE, Korolchuk VI, Kalaria RN. Severe white matter astrocytopathy in CADASIL. Brain Pathology 2018, 28(6), 832-843.
- Hase Y, Craggs L, Hase M, Stevenson W, Slade J, Chen A, Liang D, Ennaceur A, Oakley A, Ihara M, Horsburgh K, Kalaria RN. The effects of environmental enrichment on white matter pathology in a mouse model of chronic cerebral hypoperfusion. Journal of Cerebral Blood Flow and Metabolism 2018, 38(1), 151-165.
- Hase Y, Horsburgh K, Ihara I, Kalaria RN. White matter degeneration in vascular and other ageing-related dementias. Journal of Neurochemistry 2018, 144(5), 617-633.
- Duncombe J, Kitamura A, Hase Y, Ihara M, Kalaria RN, Horsburgh K. Chronic cerebral hypoperfusion: a key mechanism leading to vascular cognitive impairment and dementia. Closing the translational gap between rodent models and human vascular cognitive impairment and dementia. Clinical Science 2017, 131(19), 2451-2468.
- Hase Y, Craggs L, Hase M, Stevenson W, Slade J, Lopez D, Mehta R, Chen A, Liang D, Oakley A, Ihara M, Horsburgh K, Kalaria RN. Effects of environmental enrichment on white matter glial responses in a mouse model of chronic cerebral hypoperfusion. Journal of Neuroinflammation 2017, 14(1), 81.
- Maki T, Okamoto Y, Carare RO, Hase Y, Hattori Y, Hawkes CA, Saito S, Yamamoto Y, Terasaki Y, Ishibashi-Ueda H, Taguchi A, Takahashi R, Miyakawa T, Kalaria RN, Lo EH, Arai K, Ihara M. Phosphodiesterase III inhibitor promotes drainage of cerebrovascular beta-amyloid. Annals of Clinical and Translational Neurology 2014, 1(8), 519-533.