Molecular Mechanisms of Life
We want to uncover fundamental biological mechanisms at a molecular level.
Researching biomolecules
The biomolecules essential for life include:
- proteins
- nucleic acids
- lipids
- complex carbohydrates
These biomolecules:
- perform enzymatic reactions
- engage in molecular interactions to regulate cellular and systemic processes
- facilitate communication; recognise and respond to signals
- house, traffic and transport the contents of cells
- store, maintain and interpret the blueprint of life
Malfunctions leading to disease usually occur because of molecular-level disruptions of biomolecules.
World-leading expertise
This theme combines world-leading expertise in:
- biochemistry
- structural biology
- biophysics and analytics
- molecular biology
These advance our knowledge of biomolecular function in organisms across the tree of life.
Biology at the molecular level
We aim to understand biomolecules with regards to:
- evolution
- maturation and stability
- function
- structure and assembly into complex systems
- mechanisms of action
Our goal is to translate these discoveries into real-world applications including:
- drug discovery
- biotechnology
- nanotechnology
This research is funded by:
- UK and European Research Councils
- Wellcome Trust and other biomedical charities
- European Commission