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Molecular Mechanisms of Life

Molecular Mechanisms of Life

We want to uncover fundamental biological mechanisms at a molecular level.

Researching biomolecules

The biomolecules essential for life include:

  • proteins
  • nucleic acids
  • lipids
  • complex carbohydrates

These biomolecules:

  • perform enzymatic reactions
  • engage in molecular interactions to regulate cellular and systemic processes
  • facilitate communication; recognise and respond to signals
  • house, traffic and transport the contents of cells
  • store, maintain and interpret the blueprint of life

Malfunctions leading to disease usually occur because of molecular-level disruptions of biomolecules.

World-leading expertise

This theme combines world-leading expertise in:

  • biochemistry
  • structural biology 
  • biophysics and analytics
  • molecular biology

These advance our knowledge of biomolecular function in organisms across the tree of life.

Biology at the molecular level

We aim to understand biomolecules with regards to:

  • evolution
  • maturation and stability
  • function
  • structure and assembly into complex systems
  • mechanisms of action

Our goal is to translate these discoveries into real-world applications including:

  • drug discovery
  • biotechnology
  • nanotechnology

This research is funded by:

  • UK and European Research Councils
  • Wellcome Trust and other biomedical charities
  • European Commission