Faculty of Medical Sciences

Diagnostic & Therapeutic Technologies

Diagnostic and Therapeutic Technologies Research Group

Theme Leader

Professor Calum McNeil

Major Research Themes

  • Development of biological sensors based on electrochemical and microelectromechanical (MEMS) systems for detection of infectious organisms.
  • Development of rapid, near-patient technology platforms for quantitative measurement of biochemical markers of disease and their application to home monitoring and management.
  • Development of multi-analyte sensor array platforms and optical nanoprobes to investigate the biochemical mechanisms underlying disease and cellular processes in order to better understand how, based on molecular pathways, disease progression varies between people so that interventions can have greater impact.


Guided by clinical need, our multi-disciplinary translational research can be applied to methods, technologies and materials to improve diagnostics and therapeutics. Research expertise in basic, applied and clinical science has resulted in significant translational funding being secured from Research Councils, the EC, industry, charities and venture-capital. By any research metric the Group is at the forefront of the field at an international level.

Key Collaborations

The D&TT Research Group has collaborative links within the Faculty of Medical Sciences and across all Faculties in the University. In addition, we have an extensive national and international network of collaborators in major Research Council and European Commission projects and with industry.

Developing Researchers

The support and development of researchers and succession planning are paramount to the work of the D&TT group. This ranges from support of MRes and PhD students to post-doctoral research associates and early-career academic staff. Many of the researchers trained in the D&TT group have gone on to academic positions in some of the UK's top Universities. Importantly, we also recognise the requirement for training and development of technical and administrative support staff who are vital to research success.

Impact and Engagement

The work of the D&TT group aims to utilise Biomedical Engineering to improve rapid clinical diagnostic technologies and to engineer technological approaches which can help to elucidate the molecular pathways that cause degenerative diseases.  Our work has been highlighted in a number of public engagement and outreach activities including producing news items and videos aimed at public education of the D&TT vision of successful outcomes of collaborative multi-disciplinary research and also using social media to highlight achievements. See:


i-sense Deputy Director Professor Calum McNeil discusss i-sense digital early-warning systems for infectious diseases, as part of a film on interdisciplinary healthcare research, funded by the EPSRC.  This is part of the Royal Society of Medicine 'Doctors of the Future' programme.

d-LIVER on Euronews TV: Video feature and report are available at the Euronews-Futuris website http://www.euronews.com/2014/11/03/longer-life-for-damaged-livers/


Related websites:

Staff List

National Health Service (NHS) & Public Health England (PHE) Staff

  • Dr Dermot Neely - NHS
  • Dr Andy Sails - PHE

Professor Mark Birch-Machin
(1) Faculty Director of Business Development (2) Professor of Molecular Dermatology (3) Co-Founder PB Bioscience Ltd

Telephone: +44 (0) 191 208 5841

Dr Barry Gallacher
Reader in Engineering Dynamics

Telephone: +44 (0) 191 208 6221

Professor Colin Harwood
Professor of Molecular Microbiology

Telephone: +44 (0) 191 208 3221

Dr John Hedley
Senior Lecturer

Telephone: +44 (0) 191 208 6002

Dr Mark Hudson
Honorary Clinical Senior Lecturer

Professor David Jones
Professor of Liver Immunology

Telephone: +44 (0) 191 208 7572

Dr Neil Keegan
Senior Lecturer

Telephone: +44 (0) 191 208 3678

Telephone: +44 (0) 191 208 8520

Dr Stuart McCracken
Clinical Fellow/Honorary Consultant


Emeritus Professor Calum McNeil
Professor of Biological Sensor Systems

Professor Naeem Soomro
Honorary Professor of Urology

Telephone: +44 (0) 191 208 4300

Professor Anil Wipat
Professor of Integrative Bioinformatics

Telephone: +44 191 208 8213 or 208 3212

Professor Matthew Wright
Professor of Toxicology

Telephone: +44 (0) 191 208 7094