Major Research Themes
- Development of biological sensors based on electrochemical and microelectromechanical (MEMS) systems for detection of infectious organisms.
- Development of rapid, near-patient technology platforms for quantitative measurement of biochemical markers of disease and their application to home monitoring and management.
- Development of multi-analyte sensor array platforms and optical nanoprobes to investigate the biochemical mechanisms underlying disease and cellular processes in order to better understand how, based on molecular pathways, disease progression varies between people so that interventions can have greater impact.
Guided by clinical need, our multi-disciplinary translational research can be applied to methods, technologies and materials to improve diagnostics and therapeutics. Research expertise in basic, applied and clinical science has resulted in significant translational funding being secured from Research Councils, the EC, industry, charities and venture-capital. By any research metric the Group is at the forefront of the field at an international level.
The D&TT Research Group has collaborative links within the Faculty of Medical Sciences and across all Faculties in the University. In addition, we have an extensive national and international network of collaborators in major Research Council and European Commission projects and with industry.
The support and development of researchers and succession planning are paramount to the work of the D&TT group. This ranges from support of MRes and PhD students to post-doctoral research associates and early-career academic staff. Many of the researchers trained in the D&TT group have gone on to academic positions in some of the UK's top Universities. Importantly, we also recognise the requirement for training and development of technical and administrative support staff who are vital to research success.
Impact and Engagement
The work of the D&TT group aims to utilise Biomedical Engineering to improve rapid clinical diagnostic technologies and to engineer technological approaches which can help to elucidate the molecular pathways that cause degenerative diseases. Our work has been highlighted in a number of public engagement and outreach activities including producing news items and videos aimed at public education of the D&TT vision of successful outcomes of collaborative multi-disciplinary research and also using social media to highlight achievements. See:
i-sense Deputy Director Professor Calum McNeil discusss i-sense digital early-warning systems for infectious diseases, as part of a film on interdisciplinary healthcare research, funded by the EPSRC. This is part of the Royal Society of Medicine 'Doctors of the Future' programme.
d-LIVER on Euronews TV: Video feature and report are available at the Euronews-Futuris website http://www.euronews.com/2014/11/03/longer-life-for-damaged-livers/
National Health Service (NHS) & Public Health England (PHE) Staff
- Dr Dermot Neely - NHS
- Dr Andy Sails - PHE
Professor Mark Birch-Machin
(1) Associate Dean of Business Development and Commercial interface (2) Professor of Molecular Dermatology (3) Deputy Degree Programme Director MRes (Biotechnology) (4) Co-Founder:Genesis Genomics (now Mitomics) Inc (5) Co-Founder PB Bioscience Ltd
Telephone: +44 (0) 191 208 5841
Dr Barry Gallacher
Reader in Engineering Dynamics
Telephone: +44 (0) 191 208 6221
Professor Colin Harwood
Professor of Molecular Microbiology
Telephone: +44 (0) 191 208 3221
Dr Mark Hudson
Honorary Clinical Senior Lecturer
Professor David Jones
Professor of Liver Immunology
Telephone: +44 (0) 191 208 7572
Professor Calum McNeil
Professor of Biological Sensor Systems
Telephone: +44 (0) 191 208 6000
Professor Naeem Soomro
Honorary Professor of Urology
Telephone: +44 (0) 191 208 4300
Professor Anil Wipat
Professor of Integrative Bioinformatics
Telephone: +44 191 208 8213 or 208 3212