Faculty of Medical Sciences

Staff Profile

Professor Deborah Tweddle

Professor of Paediatric Oncology


Roles and Responsibilities

Professor of Paediatric Oncology, Newcastle University

Honorary Consultant in Paediatric & Adolescent Oncology, Great North Children's Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust

Director of Children's Cancer & Leukaemia Group (CCLG) Tumour Bank, 2016-


BSc (Hons), Experimental Immunology & Oncology. University of Manchester, 1988
MB ChB (Hons),  Bachelor of Medicine, Bachelor of Surgery, University of Manchester, 1991
Member of the Royal College of Physicians/Paediatrics and Child Health (MRCPCH), 1994
PhD, Newcastle University, 2002
Fellow of the Royal College of Paediatrics & Child Health (FRCPCH), 2005

Previous Positions

Senior Lecturer & Honorary Consultant in Paediatric & Adolescent Oncology, 2004-2011 

Lecturer & Honorary Registrar in Paediatric Oncology, 2002-2004 

Department of Health Clinician Scientist Fellowship, Newcastle University, 2002-2008

Specialist Registrar in Paediatrics, Newcastle and North Tyneside Hospitals,1999-2002
Research Registrar in Paediatric Oncology, Newcastle University, 1996-1999
LRF Fellow in Paediatric Oncology, Newcastle Hospitals 1995-1996
SHO and Senior Resident in Paediatrics, John Radcliffe Hospital, Oxford and Duke University Hospital, North Carolina, USA 1993-1995
SHO and PRHO in Medicine and Surgery, Manchester Hospitals, 1991-1992


Royal College of Paediatrics & Child Health
United Kingdom Children's Cancer and leukaemia Group (CCLG)
British Association for Cancer Research
American Association for Cancer Research
British Medical Association


NIHR Doctoral Research Fellowship Selection Committee, 2009-11

National Cancer Research Institute (NCRI) Children's Cancer & Leukaemia Clinical Studies Group, Neuroblastoma Subgroup 2010-

Newcastle Healthcare Charity Scientific Committee, 2012-

CCLG Biological Studies Steering Group, 2014-

National Cancer Research Institute (NCRI) Children's Cancer & Leukaemia Clinical Studies Group, 2016-

Chair of UK Children's Cancer & Leukaemia Group Neuroblastoma Special Interest Group, 2010-15

Medical Trustee of Neuroblastoma UK,  2010-

Friends of Rosie Charity Scientific Committee, 2016-

Honours and Awards

MB ChB with Honours, Distinction-Psychiatry, Honours- Paediatrics, Anatomy, Physiology, Biochemistry, Pharmacology, Public Health & Epidemiology
Kessel Psychiatry Prize, University of Manchester,1991
Liversege Memorial Prize for Elective Report,Boston Children's Hospital and Dana Farber Cancer Insitute,1991
Henri-Mousalli Case Presentation Award, Manchester 1992,
Young Investigator Award, Advances in Neuroblastoma Research, Bath, 1998,
Sylvia Lawler Prize, Royal Society of Medicine,London, 2001,
SPARKS Young Investigator Award, Royal College of Paediatrics & Child Health, York, 2003




Research Interests

Childhood neuroblastoma - biological, translational and clinical

Postgraduate Supervision

6 PhD students, 2 Staff PhD, 1 staff MPhil

14 MRes students. 2 MClin Res students


MRC Intercalated studentship, 1988
North of England Children's Cancer Research Fund, Clinical Fellowship, 1996-1999 
NIHR Clinician Scientist Award, 2002-2008
Cancer Research UK, PhD studentship,2003-2007
Cancer Research UK, Continuation of a national neuroblastoma molecular diagnostic service, 2004-2006
Cancer Research UK, PhD studentship,2005-2009
Cancer Research UK, Drug Development Award, 2005-2007
Neuroblastoma Society Project Grant, 2005-2008
Department of Health, Continuation of a national neuroblastoma molecular diagnostic service, 2006-2008
Cancer Research UK, PhD studentship, 2007-2011
Newcastle Healthcare Charity, 2007-2008
Newcastle Healthcare Charity, 2008-2010

Neuroblastoma Society, Neuroblastoma Reference Centre Service 2008-2011

Cancer Research UK, PhD studentship, 2010-2014

Cancer Research UK, Small Grant, 2011-2012

Neuroblastoma Society, 2010-2012

JGW Paterson Foundation, 2011-2012

Cancer Research UK, CCLG Tumour Bank, 2011-14 

NIHR, Flexibility & Sustainability Funding, 2011-12

SPARKS/DCCF, Project Grant, 2012-15

Children with Cancer, Project Grant, 2012-13

Cancer Research UK, CTAAC funding 2012-17

Newcastle Healthcare Charity, 2013-14

Families Against Neuroblastoma, 2013-14

Cancer Research UK, CCLG Tumour Bank, 2014-17

Neuroblastoma UK, Project Grant, 2014-16

Solving Kids Cancer, UK, 2015-15

Neuroblastoma UK/ Niamh's Next Step, Project Grant, 2015-17

NIHR Newcastle Biomedical Research Centre Project Grant, 2015-17

Wellcome Trust/Department of Health Healthcare Innovation Challenge Fund, 2015-18

MRC Molecular Pathology Node, 2015-18

Action Medical Research/ Great Ormond Street Hospital Children's Charity, 2016-19

JGW Paterson Foundation, 2016-17

Little Princess Trust/CCLG, 2016-17

Little Princess Trust/CCLG, 2017-18

Cancer Research UK, New Agents Grant, 2017-

Cancer Research UK, CCLG Tumour Bank, 2017-20





Medical Students on wards and clinics

Bioscience students as part of undergraduate projects


Postgraduates as part of research degrees- MRes, MClinRes, MPhil, MD, PhD

Junior doctors on wards and clinics