Newcastle Clinical Trials Unit

Staff Profile

Ruth Wood

Data Manager

Background

Introduction

I have worked with databases and data at Newcastle University since 1993, during that time I have worked on many projects in diverse clinical areas, from stroke disease to various clinical and surgical trials.  I have extensive knowledge of Microsoft Access and have developed many applications to administer and collect research data.  With the introduction of the EU Directive I have become familiar with other databases which fulfil the relevant regulations.  In NCTU we are currently using Ennov's MACRO and Sealed Envelope’s Red Pill clinical data management systems to collect research data for clinical trials.   

I have extensive experience of using both SPSS and MS Access for data cleaning activities and statistical analyses.

Roles and Responsibilities

As a Data Manager I am currently working on a number of trials, including;

MCDS-Therapy - Repurposing of Carbamazepine (CBZ) for the treatment of skeletal dysplasia.  A two-stage open-label phase I/IIa trial in outpatients including an initial dose determination stage followed by long-term assessment of efficacy and safety at the chosen dose. The trial includes an initial dose determination stage (Stage 1) followed by long-term assessment of efficacy and safety at the chosen dose (Stage 2).  Participant population: Children with a diagnosis of Metaphyseal chondrodysplasia, type Schmid (MCDS) with confirmed COL10A1 pathogenic mutation.

IBD-RESPONSE - Defining microbial predictors of responsiveness to biologic therapies in Crohn's disease and ulcerative colitis.  An observational longitudinal cohort study.

TALGiTS Trial of Alginates in Throat Symptoms (TALGiTS). A pragmatic, multicentre, placebo controlled, double blind, parallel, randomised controlled trial of liquid alginate (Gaviscon Advance) for the treatment of persistent throat symptoms.


Qualifications  

BSc (Hons) Psychology & Zoology (University of Reading)

T.E.C. Higher Certificate in Computer Technology and Electronics (Middlesex Polytechnic)

MSc Management of Information Technology (Part time Sunderland University)


Research

Research Interests

Data and information management and analyses, data science, clinical trials methodology.

Teaching

None

Publications