Background

I have a background in biological science research as well as extensive administrative experience both in the private and public sectors. 

In addition to my administrative role I also act as Wellbeing Ambassador for the Newcastle Clinical Trials Unit, and I am one of many Menopause Champions within the University.

Research

Current Trials:

• Minimally invasive thoracoscopoically-guided right minithoracotomy versus conventional sternotomy for mitral valve repair: a multicentre randomised controlled trial (UK Mini Mitral)
• Multicentre, open-label, prospective, single arm study of the safety and impact of Eculizimab withdrawal in patients with atypical haemolytic uraemic syndrome: Stopping Eculizumab Treatment Safely in aHUS (SETS aHUS)
• Obeticholic Acid for the Amelioration of Cognitive Symptoms Trial Programme (OACS-1, OACS-2, OACS-3)

Previous Trials:

• Prehabilitation in Elective Patients Undergoing Cardiac Surgery: A Randomised Controlled Trial (PrEPS)
• Control, Fludrocortisone or Midodrine for the treatment of Orthostatic Hypotension: A Randomised Controlled Trial (CONFORM-OH)

Publications

• Dominguez-Escrig JL, Kelly JD, Neal DE, King SM, Davies BR. Evaluation of the therapeutic potential of the epidermal growth factor receptor tyrosine kinase inhibitor gefitinib in preclinical models of bladder cancer. Clinical Cancer Research 2004, 10(14), 4874-4884.
• Patterson SM, Swainsbury R, Routledge EG. Antigen-specific membrane fusion mediated by the haemagglutinin protein of influenza A virus: Separation of attachment and fusion functions on different molecules. Gene Therapy 1999, 6(4), 694-702.