FACT
FACT
Effect of folic acid supplementation in pregnancy preeclampsia
- Study stage: Closed
- UK Sponsor: The Newcastle upon Tyne Hospitals NHS Foundation Trust
- Funder: Canadian Institute of Health Research (CIHR)
- Therapeutic area: Reproductive Health and Childbirth (IVF)
- Type of study: CTIMP
Aim: The overall aim of this randomized controlled trial is to evaluate a new preeclampsia (PE) prevention strategy of high dose folic acid supplementation from early (80/7 to 166/7weeks of gestation) pregnancy until delivery.
Primary Outcome:
Preeclampsia (PE) is the primary outcome measure.
PE is defined as blood pressure ≥d90 mmHg on two occasions ≥4 hours apart and proteinuria developed in women greater than 20 weeks of gestation.
- Population: Adult
- Phase: III
- Design: RCT
- Setting: Secondary Care
- Planned Sample Size: 3064