School of Natural and Environmental Sciences

Event items

Biomolecular modelling - what we can do, what we can't do - and the reasons why

Chemistry Seminar Series - Sarah Anne Harris, Theoretical Physics Group, School of Physics and Astronomy, University of Leeds

Date/Time: Tuesday 5 February 2019, 14:00 - 15:00

Venue: Room 2.76, Bedson Building

Abstract

Biomolecular simulation has been described as a “computational microscope”, which enables us to see dynamic processes and interactions that are inaccessible experimentally.

However, as with all biophysical tools, computer models have fundamental limits to their scope and applicability.

Using my own simulations of DNA supercoiling and the mechanics of the molecular motor dynein as illustrative examples, I will provide an overview of the current state of the art of biomolecular simulation.

I invite discussion of how modellers and experimentalists can best work together.