Northern Institute for Cancer Research

Stem cells and cancer

Stem cells and cancer


Stem cell biology has come of age with established roles in the maintenance of many adult tissues throughout life.

Research Leaders

Rakesh Heer
Craig Robson


Self-renewal and the effects of ageing on stem cells are key areas of interest. These cells are the likely site to accumulate mutations underpinning malignant translation in age-related adult cancers.

We investigate the intrinsic and extrinsic co-opting cancer regulators of key stem cell characteristics including:

  • self-renewal
  • plasticity
  • differentiation


Mohammad Moad

Natasha Hepburn

Emma Curry