Northern Institute for Cancer Research

Staff Profile

Dr Gareth Veal

Senior Lecturer

Background

Roles and Responsibilities

  • Management of Newcastle Cancer Centre Pharmacology Group (NCCPG)
  • Executive Board (Northern Institute for Cancer Research)
  • Lead on early phase clinical trials (PK/PD) in adult and childhood cancers
  • Coordination of national paediatric clinical pharmacology studies
  • Supervision of undergraduate, MRes and PhD student projects
  • Teaching (BSc Pharmacology; MRes Medical and Molecular Biosciences)
  • Carcinogen and Chemical Safety Officer - Northern Institute for Cancer Research

Areas of expertise

  • Clinical pharmacology studies in oncology

Qualifications

  • BSc Pharmacology (Hons), University of Liverpool
  • Ph.D. (Clinical Pharmacology), University of Liverpool

Previous Positions

  • 2005 to 2010 - Academic Fellow, Northern Institute for Cancer Research, Newcastle University.
  • 2001 to 2005 - Senior Research Associate, Northern Institute for Cancer Research, Newcastle University.
  • 1998 to 2001 - Postdoctoral Research Associate, Cancer Research Unit, Newcastle University.
  • 1996 to 1998 - Postdoctoral Fellow, Division of Experimental Medicine and Haematology/Oncology, Harvard Medical School.

Memberships

Member of the following organisations :-

  • Children’s Cancer and Leukaemia Group (CCLG) (Pharmacology Subcommittee Chair)
  • SIOP European Neuroblastoma Group (Pharmacology Subcommittee Chair)
  • NCRI Teenagers and Young Adults CSG Biological Subgroup
  • EMA European Network of Paediatric Research (Enpr-EMA) Scientific Committee
  • NIHR NCRN UK and Ireland Children's Cancer and Leukaemia Clinical Research Forum
  • Children's Brain Tumour Drug Delivery Consortium (CBTDCC)
  • NCRI Bone Sarcoma CSG Biomarker Subgroup
  • British Association for Cancer Research (BACR)
  • American Association for Cancer Research (AACR)
  • European Association for Cancer Research (EACR) 

Honours and Awards

Awards/achievements :-

  • Winner of the Quality in Care (QiC) Excellence in Oncology 'Best Innovation in Service Provision - Partnership Across the Pathway' Award for the establishment of a national therapeutic drug monitoring service for the treatment of children with cancer (December, 2013)
  • BACR Mid-Career Fellowship (£2,000) – awarded to support a collaborative visit to the Tata Memorial Hospital, India (October, 2010)
  • AACR-Merck Scholar-in-Training Award ($1,400) – received at the 100th Annual Meeting of the American Association of Cancer Research, Denver (April, 2009)
  • AACR-GlaxoSmithKline Outstanding Clinical Scholar Award ($4,000) – received at the 95th Annual Meeting of the American Association of Cancer Research, Orlando (April, 2004)
  • BACR Exchange Fellowship (£1,500) – received to support research carried out in laboratory of Dr. David Waxman, Boston University, USA (June – August, 2004)

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Research

Research Interests

My research involves the design and coordination of clinical pharmacology studies involving both adults and children with cancer. These studies are associated with a wide range of approaches to cancer treatment including the development of novel agents, early phase clinical trials, the optimisation of established therapeutics and individualisation/personalisation of patient treatment. Studies are carried out at a national and European level involving the treatment of patients at centres throughout the UK and Europe. In addition to these clinical studies, I am involved in laboratory-based molecular and pharmacological translational research projects.

Other Expertise

Other research interests/expertise include the following :-

- biomarker studies
- therapeutic drug monitoring
- pharmacogenetic studies
- clinical welfare of children involved in research studies

Funding

Cancer Research UK

NIHR Research for Patient Benefit

European Commission Horizon 2020

Wellcome Trust Health Innovation Challenge Fund

Children with Cancer UK

European Commission Seventh Framework Programme (FP7)

Medical Research Council DPFS

Medical Research Council DTA

Research Councils UK

Sarcoma UK

Sparks Children's Medical Research Charity

Newcastle University Hospitals Special Trustees


Esteem Indicators

Editorial board member for Pharmacology Research & Perspectives, Cancer Chemotherapy and Pharmacology and Frontiers in Oncology  

Reviewer for the following journals :-

- Journal of Clinical Oncology
- Clinical Cancer Research
- Molecular Cancer Therapeutics
- British Journal of Cancer
- European Journal of Cancer
- Cancer Chemotherapy and Pharmacology
- Clinical Pharmacokinetics
- Therapeutic Drug Monitoring
- Pediatric Blood and Cancer
- British Journal of Pharmacology
- Expert Opinion on Drug Delivery
- Pediatric Hematology and Oncology
- BMC Cancer
- Frontiers in Pediatric Oncology
 

Teaching

Undergraduate Teaching

BSc (Hons) Pharmacology

PED2001: Drug disposition and pharmacokinetics

PED3006: Carcinogenesis and anticancer drugs

Pharmacy MPharm Honours

PHAR2006: Pharmaceutical Care - pathology, patients and professionalism


Postgraduate Teaching

MRes in Medical and Molecular Biosciences (MMS8007: Cancer Studies)

MSc Medical Sciences (MMS8101: Research Practice in the 21st Century; MMS8107: Cancer Studies)

 

Publications